Results 61 to 70 of about 5,354 (166)

Microbial metabolites in tumor epigenetic regulation

iMeta, Volume 5, Issue 1, February 2026.
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang, Haoling Zhang, Yan Liao, Shuya Jiang, Haolong Zhang, Chenwei Huang, Zhijing Song, Rui Zhao, Ping Lu, Xiaohong Kang, Eryan Kong, Yalin Zhu, Wei Wang, Xuesong Liu, Yisheng Chen, Zhiwen Luo, Zhaoyu Li, Di Wang, Na Xing, Yadong Guo, Jingjing Zhang, Xiaojing Wang, Wenyi Wang, Mowaffaq Adam, Bakiah Shaharuddin, Muhamad Yusri Musa, Doblin Sandai, Chenglong Zhu, Aimin Jiang, Peng Luo, Zhijie Zhao, Zui Zou   +31 more
wiley   +1 more source

Direct Bioelectrocatalysis via Interdomain Electron Transfer of Fungal Pyrroloquinoline Quinone-dependent Pyranose Dehydrogenase Depending on the Alkyl Chain Lengths of Self-assembled Monolayers

Electrochemistry
Direct electron transfer (DET)-enabled oxidoreductase has been utilized to develop mediator-free bioelectronic devices. Fungal pyrroloquinoline quinone-dependent dehydrogenase from Coprinopsis cinerea is an attractive quinohemoprotein in which the ...
Kota TAKEDA, Tatsuki MINAMI, Makoto YOSHIDA, Kiyohiko IGARASHI, Nobuhumi NAKAMURA   +4 more
doaj   +1 more source

Cryo‐EM Analysis in CASP16

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 1, Page 447-459, January 2026.
ABSTRACT Since CASP13, experimentalists have been encouraged to provide their cryo‐EM data along with the derived atomic models to the CASP organizers to aid assessment. In CASP16, 38 cryo‐EM datasets were provided for assessment, which represented most cryo‐EM targets.
Thomas Mulvaney, Andriy Kryshtafovych, Maya Topf   +2 more
wiley   +1 more source

16S rRNA Gene Amplicon Sequencing and Functional Profiling of Rhizosphere Bacteria in Date Palms Reveal Diverse Potential Plant Growth–Promoting Traits

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
The rhizosphere of date palm trees serves as a reservoir for plant growth–promoting bacteria (PGPB). To characterize the microbial communities and associated PGP traits within these rhizospheres, Illumina amplicon sequencing of 16S rRNA genes and Phylogenetic Investigation of Communities by Reconstruction of Unobserved States (PICRUSt) analysis were ...
Sultan M. Alsharif, Mohamed Ismaeil, Hibah M. Albasri, Wael S. El-Sayed, Shweta Negi   +4 more
wiley   +1 more source

Molecular Mechanisms of Plant Growth–Promoting Rhizobacteria (PGPR) in Biofertilization and Disease Suppression of Crops

International Journal of Agronomy, Volume 2026, Issue 1, 2026.
Plant growth–promoting rhizobacteria (PGPR) are beneficial soil bacteria that colonize the rhizosphere and enhance plant growth through direct and indirect mechanisms, including nutrient solubilization, phytohormone production, suppression of phytopathogens, and activation of plant defense mechanisms.
Etsay Mesele, Gebremedhin Gebreslassie, Ashenafi Teklay Yaekob, Tesfakiros Semere, Maria Serrano   +4 more
wiley   +1 more source

Targeting Multilayered Metabolic Networks in Brain Diseases: Emerging Perspectives on Nanodelivery Strategies

Advanced Science, Volume 12, Issue 41, November 6, 2025.
Brain diseases involve multilayered metabolic disruptions that reshape cellular interactions and microenvironments. This review outlines core metabolic features across disease states and presents emerging nanodelivery strategies as precision tools to reprogram pathological metabolism.
Jingyi Zhou, Chen Jiang
wiley   +1 more source

Pyrolyzed Walnut Shell‐Based Flexible Electrodes for Magnetically Triggered ON/OFF DNA Release

Advanced NanoBiomed Research, Volume 5, Issue 10, October 2025.
A magnetically actuated DNA release system using walnut shell‐derived electrodes enables ON/OFF switching of electron transfer by controlling DNA hybridization with magnetic beads. A magnetically gated, enzymatically driven DNA release platform based on sustainable pyrolyzed walnut shell‐derived carbon electrodes is reported.
Paolo Bollella, Blanca Cassano, Verdiana Marchianò, Angelo Tricase, Eleonora Macchia, Luisa Torsi   +5 more
wiley   +1 more source

Portable multimodal sensing system for screening of diabetes mellitus from human urine

VIEW, Volume 6, Issue 5, October 2025.
A compact multimodal sensing device was developed for the simultaneous detection of glucose and acetone from urine samples. Combining electrochemical and gas sensors, the device demonstrates reliable performance within clinically relevant ranges. This portable system offers a holistic metabolic assessment, supporting early screening of diabetes and ...
Mario Soto Martinez, Yurii Tsyban, Alexander Przybysz, Abdullah Bukhamsin, Yuvaraj Sivalingam, Khaled Nabil Salama   +5 more
wiley   +1 more source

Microgravity effects on secondary metabolism of plant-affecting bacteria

Microbiology Spectrum
Despite their miniscule mass, microgravity has been shown to impose physiological stresses on bacteria, leading to altered gene regulation and metabolic output in unpredictable ways.
Gayatri Sharma, Mohammed M. A. Ahmed, Tahir Ali, Paul D. Boudreau, Patrick D. Curtis   +4 more
doaj   +1 more source

Engineered neuronal exosomes mediate α-synuclein clearance to ameliorate Parkinson’s disease

Journal of Nanobiotechnology
Parkinson’s disease (PD) is the second most common neurodegenerative disorder after Alzheimer’s disease. A hallmark pathological feature of PD is the abnormal aggregation of α-synuclein (αSyn) into insoluble Lewy bodies.
Lufei Chen, Xiaoling Lin, Mingzhi Fu, Shenglang Chen, Zhexiao Yan, Yuelin Diao, Genyu Chen, Zichen Huang, Yan Sun, Yaxin Lin, Zucheng Ye, Ying Zhou, Qinyong Ye   +12 more
doaj   +1 more source