Results 91 to 100 of about 4,988 (210)

Identification of transcriptional networks responding to pyrroloquinoline quinone dietary supplementation and their influence on thioredoxin expression, and the JAK/STAT and MAPK pathways [PDF]

, 2010
PQQ (pyrroloquinoline quinone) improves energy utilization and reproductive performance when added to rodent diets devoid of PQQ. In the present paper we describe changes in gene expression patterns and transcriptional networks that respond to dietary ...
Ameyama, Asin-Cayuela, Bauerly, Bookout, Bookout, Cadenas, Calliandra Harris, Chowanadisai, Cochem, Diez, Eskouhie Tchaparian, Felton, Gene Cutler, Hagmeyer, Hamagishi, Hirakawa, Ishii, Johannsen, Kaipio, Kalinina, Kasahara, Kathryn Bauerly, Kumazawa, Kumazawa, Kumazawa, Kumazawa, Li, Lisa Marshal, Liu, Matsushita, Michael Satre, Mitchell, Naito, Nunome, Ramakrishnan, Rebagliati, Robert B. Rucker, Rucker, Rucker, Rudolf, Smidt, Smidt, Spiegelman, Steinberg, Steinberg, Stites, Takeda, Tusher, Van Laethem, Vermeulen, Wang, Wang, Wegrzyn, Winyoo Chowanadisai, Wong, Wu, Zang, Zhang, Zhang, Zhang, Zhu, Zhu   +61 more
core   +2 more sources

The Elusive Chemistry of Pyrroloquinoline Quinone Dimethyl Ester Lanthanide Complexes in Biomimetic Alcohol Oxidation

European Journal of Inorganic Chemistry, Volume 28, Issue 24, August 29, 2025.
Biomimetic complexes of lanthanide‐dependent methanol dehydrogenases bearing a pyrroloquinoline quinone dimethyl ester ligand can oxidize alcohols to aldehydes. Spectroscopic studies on the reaction shed light on the mechanism of the reaction and may explain trends observed in the enzyme.
Ioana Ciubotaru, Lisa C. Biener, Violeta A. Vetsova, Patrick Weis, Michael Seitz, Lena J. Daumann   +5 more
wiley   +1 more source

Deep Learning‐Driven Exploration of Pyrroloquinoline Quinone Neuroprotective Activity in Alzheimer's Disease

Advanced Science
Alzheimer's disease (AD) is a pressing concern in neurodegenerative research. To address the challenges in AD drug development, especially those targeting Aβ, this study uses deep learning and a pharmacological approach to elucidate the potential of ...
Xinuo Li, Yuan Sun, Zheng Zhou, Jinran Li, Sai Liu, Long Chen, Yiting Shi, Min Wang, Zheying Zhu, Guangji Wang, Qiulun Lu   +10 more
doaj   +1 more source

Pyrroloquinoline Quinone Inhibits Rotenone-Induced Microglia Inflammation by Enhancing Autophagy

Molecules, 2020
Neuroinflammation is a feature common to neurodegenerative diseases, such as Parkinson’s disease (PD), which might be responsive to therapeutic intervention.
Qi Zhang, Jing Zhou, Mi Shen, Hui Xu, Shu Yu, Qiong Cheng, Fei Ding   +6 more
doaj   +1 more source

The TonB‐Dependent Transport System Facilitates the Uptake of Inorganic Metal Mediators in Pseudomonas putida KT2440 in a Bioelectrochemical System

Microbial Biotechnology, Volume 18, Issue 8, August 2025.
Mediator‐based extracellular electron transfer in Pseudomonas putida KT2440 relies on the TonB‐dependent system for effective mediator (ferricyanide) transport. Transcriptomic and functional analyses confirmed its key role, while OprF overexpression enhanced membrane permeability and current output. These findings clarify mediator uptake mechanisms and
Anna Weimer, Jens Krömer, Bin Lai, Christoph Wittmann   +3 more
wiley   +1 more source

Pyrroloquinoline quinone regulates the redox status in vitro and in vivo of weaned pigs via the Nrf2/HO-1 pathway

Journal of Animal Science and Biotechnology, 2021
Background Oxidative stress is a main cause of piglet gut damage and diarrhea. Pyrroloquinoline quinone (PQQ), is a novel redox cofactor with antioxidant properties. However, the effect and mechanism that PQQ supplementation decreases oxidative injury in
Caiyun Huang, Zijuan Fan, Dandan Han, Lee J. Johnston, Xi Ma, Fenglai Wang   +5 more
doaj   +1 more source

Targeting Drp1 in Cerebral Ischemia–Reperfusion Injury: Mechanisms and Therapeutic Implications

CNS Neuroscience &Therapeutics, Volume 31, Issue 8, August 2025.
This review highlights the central role of dynamin‐related protein 1 (Drp1) in cerebral ischemia–reperfusion injury (CIRI), emphasizing its involvement in mitochondrial dysfunction, oxidative stress, and neuronal injury. Drp1 is presented as a promising therapeutic target for CIRI, with evidence suggesting that modulating its activity can alleviate ...
Mengnan Liu, Zhixue Yin, Binru Li, Ji Qiu, Dechou Zhang, Raoqiong Wang, Xue Bai, Li Chen   +7 more
wiley   +1 more source

Increasing the diversity of leguminous plant improves soil functionalities and wheat growth in a P-deficient soil [PDF]

, 2014
A study was conducted in glasshouse conditions to assess the influences of the leguminous plant diversity on the soil microbial functions and their consequences on the wheat growth. Three legume species were targeted: faba bean, alfalfa and pea.
Baudoin, Ezékiel, Duponnois, Robin, Galiana, Antoine, Hafidi, Mohamed, Maghraoui, Tasnime, Prin, Yves, Sanguin, Hervé, Tournier, Estelle, Wahbi, Sanâa   +8 more
core  

Crystal structure and characterization of pyrroloquinoline quinone disodium trihydrate

Chemistry Central Journal, 2012
Background Pyrroloquinoline quinone (PQQ), a tricarboxylic acid, has attracted attention as a growth factor, and its application to supplements and cosmetics is underway.
Ikemoto Kazuto, Sakamoto Hitoshi, Nakano Masahiko   +2 more
doaj   +1 more source

Aspects of the Release of Superoxide by Leukocytes, and a Means by Which This Is Switched Off [PDF]

, 2010
Although great progress has been made in understanding the respiratory burst of leukocytes that produce superoxide (O2-), it is possible that a component or components, might have been overlooked.
Bishop, Amy, Camerero, Valeria C.P.C., Colepicolo, Pio, Gallop, Paul M., Karnovsky, Manfred L., Paz, Mercedes Aurora, Ribeiro, Jose M.C.   +6 more
core