Results 111 to 120 of about 23,834 (239)

Deletion of Skeletal Muscle Mitochondrial Glutamic‐Oxaloacetic Transaminase (GOT2) Enhances Oxaloacetate Inhibition of Succinate Dehydrogenase and Alters Substrate Selectivity

The FASEB Journal, Volume 39, Issue 14, 31 July 2025.
Oxaloacetate is centrally positioned in the TCA cycle to regulate critical metabolic steps. Deletion of mitochondrial glutamic‐oxaloacetic transaminase (GOT2) increases oxaloacetate accumulation and inhibits succinate dehydrogenase (SDH or complex II).
Brian D. Fink, Ritu Som, Liping Yu, William I. Sivitz   +3 more
wiley   +1 more source

Case Report: Prenatal neurological injury in a neonate with pyruvate carboxylase deficiency type B. [PDF]

Front Endocrinol (Lausanne), 2023
Xue M.
europepmc   +1 more source

Immunodetection of Pyruvate Carboxylase Expression in Human Astrocytomas, Glioblastomas, Oligodendrogliomas, and Meningiomas. [PDF]

Neurochem Res, 2023
Gondáš E, Kráľová Trančíková A, Dibdiaková K, Galanda T, Hatok J, Račay P, Dobrota D, Murín R.   +7 more
europepmc   +1 more source

Pyruvate Carboxylase

, 1965
Michael C. Scrutton, Merton Utter
openalex   +1 more source

In silico Analysis of Two Novel Variants in the Pyruvate Carboxylase (PC) Gene Associated with the Severe Form of PC Deficiency. [PDF]

Iran Biomed J, 2023
Maryami F, Rismani E, Davoudi-Dehaghani E, Khalesi N, Talebi S, Mahdian R, Zeinali S.   +6 more
europepmc   +1 more source

Requirement of hepatic pyruvate carboxylase during fasting, high fat, and ketogenic diet. [PDF]

J Biol Chem, 2022
Selen ES, Rodriguez S, Cavagnini KS, Kim HB, Na CH, Wolfgang MJ.   +5 more
europepmc   +1 more source

Conformational Selection Governs Carrier Domain Positioning in Staphylococcus aureus Pyruvate Carboxylase. [PDF]

Biochemistry, 2022
Hakala JH, Laseke AJ, Koza AL, St Maurice M.   +3 more
europepmc   +1 more source

Subcellular Distribution of Pyruvate Carboxylase, Diphosphopyridine Nucleotide and Triphosphopyridine Nucleotide Isocitrate Dehydrogenases, and Malate Enzyme in Rat Brain

, 1968
Leon Salganicoff, Roger E. Koeppe
openalex   +1 more source

LDHB contributes to the regulation of lactate levels and basal insulin secretion in human pancreatic β cells

Cell Reports
Summary: Using 13C6 glucose labeling coupled to gas chromatography-mass spectrometry and 2D 1H-13C heteronuclear single quantum coherence NMR spectroscopy, we have obtained a comparative high-resolution map of glucose fate underpinning β cell function ...
Federica Cuozzo, Katrina Viloria, Ali H. Shilleh, Daniela Nasteska, Charlotte Frazer-Morris, Jason Tong, Zicong Jiao, Adam Boufersaoui, Bryan Marzullo, Daniel B. Rosoff, Hannah R. Smith, Caroline Bonner, Julie Kerr-Conte, Francois Pattou, Rita Nano, Lorenzo Piemonti, Paul R.V. Johnson, Rebecca Spiers, Jennie Roberts, Gareth G. Lavery, Anne Clark, Carlo D.L. Ceresa, David W. Ray, Leanne Hodson, Amy P. Davies, Guy A. Rutter, Masaya Oshima, Raphaël Scharfmann, Matthew J. Merrins, Ildem Akerman, Daniel A. Tennant, Christian Ludwig, David J. Hodson   +32 more
doaj  

Immunochemical studies with soluble and mitochondrial pyruvate carboxylase activities from rat tissues [PDF]

, 1970
F J Ballard, Richard W. Hanson, Lea Reshef   +2 more
openalex   +1 more source