Results 141 to 150 of about 141,799 (322)

Protective effects of all-trans retinoic acid against gastric premalignant lesions by repressing exosomal LncHOXA10–pyruvate carboxylase axis

open access: green, 2021
Chen Wang   +12 more
openalex   +2 more sources

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

open access: yesExperimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer   +11 more
wiley   +1 more source

Design, synthesis and structure–activity relationship studies on erianin analogues as pyruvate carboxylase inhibitors in hepatocellular carcinoma cells

open access: bronze, 2023
Hailong Shi   +11 more
openalex   +2 more sources

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson   +7 more
wiley   +1 more source

Pyruvate Carboxylase

open access: yesJournal of Biological Chemistry, 1965
Michael C. Scrutton   +2 more
openaire   +2 more sources

Isolating the effects of carbohydrate and lipid availability on exercise‐induced skeletal muscle signalling in males

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend It is currently unknown whether the effects of low carbohydrate avalability on exercise‐induced skeletal muscle signalling and adaptations are due to the low carbohydrate availability per se, or the comcomittant high fatty acid availability. Comparing exercise after extended overnight fasting, with carbohydrate ingestion and with
Louise Bradshaw   +13 more
wiley   +1 more source

Understanding the Role of pH Regulation and Neutralizing Agents in Organic Acid Production and Growth of Aspergillus oryzae

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 1, Page 116-133, January 2026.
We show that pH and neutralization strategy strongly influence the growth, pellet morphology, and organic acid production of Aspergillus oryzae. Acidic and alkaline conditions lead to hairy, dispersed pellets, while near‐neutral environments favour compact pellet formation.
Lukas Hartmann   +4 more
wiley   +1 more source

Peroxisome proliferator-activated receptor α (PPARα) protects against oleate-induced INS-1E beta cell dysfunction by preserving carbohydrate metabolism [PDF]

open access: yes, 2018
Aims/hypothesis: Pancreatic beta cells chronically exposed to fatty acids may lose specific functions and even undergo apoptosis. Generally, lipotoxicity is triggered by saturated fatty acids, whereas unsaturated fatty acids induce lipodysfunction, the ...
Bartley, C.   +7 more
core  

Coexistence of Wolbachia with Buchnera aphidicola and a secondary symbiont in the aphid Cinara cedri.

open access: yes, 2004
Intracellular symbiosis is very common in the insect world. For the aphid Cinara cedri, we have identified by electron microscopy three symbiotic bacteria that can be characterized by their different sizes, morphologies, and electrodensities.
García-Verdugo, José Manuel   +6 more
core   +2 more sources

Sulfated Polysaccharides in the Hallmarks of Metabolic Syndrome: Functions and Mechanisms

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
The SPs sources are very diverse, including various fishes, sea cucumbers, seaweeds, etc. These SPs are able to improve the glucose and lipid metabolism disorders, hormonal dysregulation, oxidative stress, inflammatory response, complications, and gut homeostasis of MetS by regulating biochemical indicators related to MetS. ABSTRACT Metabolic syndrome (
Fuqiang Zhao   +9 more
wiley   +1 more source

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