Results 51 to 60 of about 27,529 (245)

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

Animal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar, Muhammad Arslan Asif, Layla Al‐Mitib, Nabeela Ashiq, Haojie Wang, Yalei Cui, Boshuai Liu, Shucheng Huang, Yinghua Shi   +8 more
wiley   +1 more source

Acute control of fatty acid synthesis by cyclic AMP in the chick liver cell: possible site of inhibition of citrate formation.

Journal of Lipid Research, 1979
Glucagon and N,(6)O(2)-dibutyryl cyclic adenosine 3‘,5‘-cyclic monophosphate (Bt(2)cAMP) inhibit fatty acid synthesis from acetate by more than 90% and prevent citrate formation in chick hepatocytes metabolizing glucose.
S D Clarke, P A Watkins, M D Lane
doaj   +1 more source

My favorite pyruvate carboxylase [PDF]

IUBMB Life, 2010
Having completed a PhD in molecular and cellular biology in mammalian reproduction at the University of Sydney, my first postdoctoral appointment began early in 1965 in the laboratory of Sir Hans Krebs at Oxford University where I had the pleasure of working with Dr Eric Newsholme on the regulation of gluconeogenesis and glycolysis during fetal ...
openaire   +2 more sources

Pyruvate carboxylase and pyruvate dehydrogenase enzyme activities, expression and protein levels.

, 2014
(A) Enzymatic activities (n = 3), transcript levels (n = 9), and protein levels (n = 3) for pyruvate carboxylase (green) and pyruvate dehydrogenase (purple) in NHA IDHmut cells expressed as a percentage of their IDHwt counterparts.
Pia Eriksson (405859), Myriam M. Chaumeil (632682), Sabrina M. Ronen (342173), Aaron E. Robinson (140561), Larry M. Cai (632681), Jose L. Izquierdo-Garcia (405860), Joanna J. Phillips (140583), Russell O. Pieper (221241)   +7 more
core   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Effect of Nitrate and Ammonium Nutrition of Nonnodulated Phaseolus vulgaris L. on Phosphoenolpyruvate Carboxylase and Pyruvate Kinase Activity

, 1985
Young bean plants (Phaseolus vulgaris L. var Saxa) were fed with 3.5 or 10 millimolar N in either the form of NO3− or NH4+, after being grown on N-free nutrient solution for 8 days. The pH of the nutrient solutions was either 6 or 4.
Erismann, Karl Hans, Schweizer, Patrick
core   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Pyruvate carboxylase supports the pulmonary tropism of metastatic breast cancer

Breast Cancer Research, 2018
Background Overcoming systemic dormancy and initiating secondary tumor grow under unique microenvironmental conditions is a major rate-limiting step in metastatic progression.
Aparna Shinde, Tomasz Wilmanski, Hao Chen, Dorothy Teegarden, Michael K. Wendt   +4 more
doaj   +1 more source

Increase in translatable mRNA for mitochondrial pyruvate carboxylase during differentiation of 3T3 preadipocytes

, 1981
During differentiation of 3T3 preadipocytes into adipocytes the activity of pyruvate carboxylase, a key lipogenic enzyme, rises about 20-fold. This increase of enzymatic activity is correlated with a comparable rise in the rate of incorporation of [ 35S ...
Kelly, Thomas J, Angus, C.William, Lane, M.Daniel, Rosenfeld, Philip J   +3 more
core   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source