Results 41 to 50 of about 13,382 (149)

ZmmiR1432‐ZmCML21‐ZmPMA2 Module Affects Maize Low Phosphate Tolerance via Regulating Organic Acid Secretion

Plant Biotechnology Journal, EarlyView.
ABSTRACT Phosphorus is indispensable in agricultural production. The growing global demand for food necessitates the development of crops with enhanced phosphorus utilisation efficiency. However, the molecular mechanisms coordinating phosphorus utilisation efficiency in plants remain incompletely characterised.
Laming Pei, Yaqing Yang, Zhe Wang, Wencheng Duan, Ning Liu, Zhaohua Ding, Hui Li   +6 more
wiley   +1 more source

Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice [PDF]

, 2017
Disruption of the Gys2 gene encoding the liver isoform of glycogen synthase generates a mouse strain (LGSKO) that almost completely lacks hepatic glycogen, has impaired glucose disposal, and is pre-disposed to entering the fasted state.
DePaoli-Roach, Anna A., Irimia, Jose M., Meyer, Catalina M., Morral, Nuria, Roach, Peter J., Segvich, Dyann M., Surendran, Sneha   +6 more
core   +1 more source

Metabolic profiles of six African cultivars of cassava (Manihot esculenta Crantz) highlight bottlenecks of root yield [PDF]

, 2020
Open Access Article; Published online: 17 Jan 2020Cassava is an important staple crop in sub‐Saharan Africa, due to its high productivity even on nutrient poor soils.
Fernie, A.R., Gisel, A., Klemens, P.A.W., Ludewig, F., Morales, N., Muller, L.A., Neuhaus, H.E., Obata, T., Rosado-Souza, L., Schlereth, A., Sonnewald, U., Stavolone, L., Stitt, M., Zeeman, S.C., Zierer, W.   +14 more
core   +3 more sources

ZmTH1 Is Vital for Healthy Plant Growth and Promotes Cold/Drought Tolerance by Regulating Thiamin Diphosphate‐Dependent Metabolisms in Maize

Plant Biotechnology Journal, EarlyView.
ABSTRACT Vitamin B1 (VB1) plays a crucial role in sustaining plant health and enabling adaptive responses to environmental stress. The complex maize genome implies a sophisticated VB1 synthesis pathway, with the mechanisms by which VB1 benefits plants remaining elusive.
Tengfei Zhang, Jie Zang, Boming Yang, Qiuxia Wang, Jijun Yan, Peiyong Xin, Jinfang Chu, Huabang Chen, Zhaogui Zhang   +8 more
wiley   +1 more source

Synthetic Biology and Metabolic Engineering of Microalgae for Sustainable Lipid and Terpenoid Production: An Updated Perspective

Plant Biotechnology Journal, EarlyView.
ABSTRACT Microalgae are increasingly recognised as powerful platforms for the sustainable production of lipids and terpenoids, with expanding applications in the food, fuel and biomanufacturing industries. In this updated review, we consolidate and critically assess the most recent advances in synthetic biology and metabolic engineering of key ...
Ty Shitanaka, Yu Wang, Sally Do, Julia Yuson, Samir Kumar Khanal, Krzysztof Zienkiewicz, Zhi‐Yan Du   +6 more
wiley   +1 more source

The biochemical basis of disease [PDF]

, 2018
Understanding Biochemistry is an essential online resource for post-16 students, teachers and undergraduates, providing up-to-date overviews of key concepts in biochemistry and molecular biosciences.
Ahlqvist, Alastair J. Barr, Arteaga, Baynes, Cancer Research UK 2018, Carey, Christakos, Clemens, Diabetes UK - The Cost of Diabetes, Druker, Feingold, Graham, Grove, Hanahan, Hanahan, Hantschel, Heinecke, IDF Diabetes Atlas - 8th Edition, Kagnoff, Kamangar, Keys, Knudson, Kumar, Leiva, Maher, Mann, Masters, McLannahan, NHS - Do I need vitamin supplements, NIH - AIDS Information 2018, NIH - Office of dietary supplements, NIH Genetics Home Reference - Phenylketonurea 2018, Osna, Papaemmanuil, Pecorino, Ramagopalan, Rang, Reilly, Rich, Ridaura, Samuel, Schulz, Seeley, The Cancer Genome Atlas 2018, Wang, Watts, Weinberg, Wilen, World Health Organization, World Health Organization - Cancer 2018, World Health Organization - Cholera 2018, World Health Organization - HIV/AIDS 2018, Yarden   +52 more
core   +1 more source

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

Experimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer, Dena Lin, Alec Hanshew, Jackson Stewart, Steven Ball, Christa Lilly, Saina S. Prabhu, Kate Karelina, Eric E. Kelley, Randy W. Bryner, Dharendra Thapa, Paul D. Chantler   +11 more
wiley   +1 more source

Molecular regulators of glucose and lipid metabolism in skeletal muscle [PDF]

, 2012
Skeletal muscle is a primary site of insulin action and insulin-stimulated glucose transport and occupies a center stage in maintaining whole body glucose and lipid homeostasis.
Kulkarni, Sameer S
core   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source

Molecular mechanism of dominant expression in 3-methylcrotonyl-CoA carboxylase deficiency [PDF]

, 2018
Summary: Most enzyme deficiencies in humans are inherited as autosomal recessive traits. The term dominant negative is applied to mutant alleles in which a mutant protein interferes in one way or another with the function of the normal protein being ...
Baumgartner, M.
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