Results 31 to 40 of about 158,743 (322)

In vivo metabolic imaging of Traumatic Brain Injury. [PDF]

, 2017
Complex alterations in cerebral energetic metabolism arise after traumatic brain injury (TBI). To date, methods allowing for metabolic evaluation are highly invasive, limiting our understanding of metabolic impairments associated with TBI pathogenesis ...
Chaumeil, Myriam M, Chou, Austin, Feng, Xi, Guglielmetti, Caroline, Krukowski, Karen, Najac, Chloe, Riparip, Lara-Kirstie, Rosi, Susanna   +7 more
core   +2 more sources

Regulation of Cardiac-Specific Proteins Expression by Moderate-Intensity Aerobic Exercise Training in Mice With Myocardial Infarction Induced Heart Failure Using MS-Based Proteomics

Frontiers in Cardiovascular Medicine, 2021
This study aims to systematically reveal the changes in protein levels induced by regular exercise in mice with ischemic-induced heart failure (HF). Aerobic exercise training for the ischemic-induced HF mice lasted for 4 weeks and then we used the liquid
Shouling Mi, Shouling Mi, Hao Jiang, Hao Jiang, Lei Zhang, Zhonglei Xie, Zhonglei Xie, Jingmin Zhou, Jingmin Zhou, Aijun Sun, Aijun Sun, Aijun Sun, Hong Jin, Hong Jin, Junbo Ge, Junbo Ge, Junbo Ge   +16 more
doaj   +1 more source

The relationships between transketolase, yeast pyruvate decarboxylase and pyruvate dehydrogenase of the pyruvate dehydrogenase complex [PDF]

FEBS Letters, 1993
The amino acid sequences of four thiamine pyrophosphate‐requiring enzymes were aligned with the published amino acid sequence of the transketolase of Hansenula polymorpha. Sequences of the combined α and β subunits of the E1 enzyme of the pyruvate dehydrogenase complexes of Homo sapiens and Bacillus stearothermophilus aligned well with the ...
Robinson, Brian H., Chun, Kathy
openaire   +2 more sources

Characterization and epitope mapping of human monoclonal antibodies to PDC-E2, the immunodominant autoantigen of primary biliary cirrhosis [PDF]

, 1992
Further to define the epitopes of PDC-E2, the major autoantigen in primary biliary cirrhosis (PBC), we have developed and characterized five human monoclonal antibodies. These antibodies were derived by fusing a regional hepatic lymph node from a patient
Bassendine, Baum, Casali, Chambers, Coppel, Coppel, Cram, Flannery, Fregeau, Fregeau, Fujikura, Fusey, Fussey, Gershwin, Gershwin, Griffin, Griffin, James, Kaplan, Kunicki, Larrick, Leung, Leung, Mackay, Mackay, Mathews, McNeilage, Okamoto, Pollack, Ramsden, Reeves, Reimer, Robbins, Rokeach, Rowley, Ruther, Salemuddin, Sturgess, Sudin, Surh, Surh, Surh, Surh, Tan, Uibo, Van de Water, Van de Water, Van de Water, Van de Water, Williams   +49 more
core   +1 more source

Minimizing acetate formation in E. coli fermentations [PDF]

, 2007
Escherichia coli remains the best established production organisms in industrial biotechnology. However, during aerobic fermentation runs at high growth rates, considerable amounts of acetate are accumulated as by-product.
De Maeseneire, Sofie, De Mey, Marjan, Soetaert, Wim, Vandamme, Erick   +3 more
core   +2 more sources

Rg3 regulates myocardial pyruvate metabolism via P300-mediated dihydrolipoamide dehydrogenase 2-hydroxyisobutyrylation in TAC-induced cardiac hypertrophy

Cell Death and Disease, 2022
The failing heart is characterized by an increase in glucose uptake and glycolytic rates that is not accompanied by a concomitant increase in glucose oxidation.
Jingyu Ni, Hao Zhang, Xiaodan Wang, Zhihao Liu, Tong Nie, Lan Li, Jing Su, Yan Zhu, Chuanrui Ma, Yuting Huang, Jingyuan Mao, Xiumei Gao, Guanwei Fan   +12 more
doaj   +1 more source

Incomplete Wood-Ljungdahl pathway facilitates one-carbon metabolism in organohalide-respiring Dehalococcoides mccartyi. [PDF]

, 2014
The acetyl-CoA "Wood-Ljungdahl" pathway couples the folate-mediated one-carbon (C1) metabolism to either CO2 reduction or acetate oxidation via acetyl-CoA.
Alvarez-Cohen, Lisa, Bill, Markus, Brisson, Vanessa L, Conrad, Mark E, Feng, Xueyang, Men, Yujie, Tang, Yinjie J, Yi, Shan, Zhuang, Wei-Qin   +8 more
core   +1 more source

A Substrate-induced Biotin Binding Pocket in the Carboxyltransferase Domain of Pyruvate Carboxylase [PDF]

, 2013
Biotin-dependent enzymes catalyze carboxyl transfer reactions by efficiently coordinating multiple reactions between spatially distinct active sites. Pyruvate carboxylase (PC), a multifunctional biotin-dependent enzyme, catalyzes the bicarbonate- and ...
Lietzan, Adam D, Maurice, Martin St.
core   +2 more sources

LC-MS proteomics analysis of the iInsulin/IGF-1-deficient Caenorhabditis elegans daf-2(e1370) mutant reveals extensive restructuring of intermediary metabolism [PDF]

, 2014
The insulin/IGF-1 receptor is a major known determinant of dauer formation, stress resistance, longevity, and metabolism in Caenorhabditis elegans. In the past, whole-genome transcript profiling was used extensively to study differential gene expression ...
Braeckman, Bart, Brewer, Heather M, Camp, David G, II, Depuydt, Geert, Petyuk, Vladislav A, Smith, Richard D, Smolders, Arne, Xie, Fang   +7 more
core   +2 more sources

A novel null mutation in the pyruvate dehydrogenase phosphatase catalytic subunit gene (PDP1) causing pyruvate dehydrogenase complex deficiency

JIMD Reports, 2019
Congenital lactic acidosis due to pyruvate dehydrogenase phosphatase (PDP) deficiency is very rare. PDP regulates pyruvate dehydrogenase complex (PDC) and defective PDP leads to PDC deficiency.
Jirair K. Bedoyan, Leah Hecht, Shulin Zhang, Stacey Tarrant, Ann Bergin, Didem Demirbas, Edward Yang, Ha Kyung Shin, George J. Grahame, Suzanne D. DeBrosse, Charles L. Hoppel, Douglas S. Kerr, Gerard T. Berry   +12 more
doaj   +1 more source