Results 171 to 180 of about 40,891 (231)

Recent Advances on the Role of B Vitamins in Cancer Prevention and Progression. [PDF]

Int J Mol Sci
Frost Z, Bakhit S, Amaefuna CN, Powers RV, Ramana KV.   +4 more
europepmc   +1 more source

Magnetite Micro/Nanorobots for Efficient Targeted Alleviation of Inflammatory Bowel Disease

Advanced Science, Volume 12, Issue 26, July 10, 2025.
Improved reactive oxygen species scavenging capacities of functionalized micro/nanorobots (MNRs) are useful for the treatment of inflammatory bowel disease (IBD). MNRs can break the harmful bacteria in IBD, thereby eliminating inflammation and restoring the intestinal barrier function.
Ying Feng, Yang Liu, Linlin Liu, Qian Yang, Miao An, Huaming Yang   +5 more
wiley   +1 more source

Pyruvate dehydrogenase deficiency in a female due to a 4 base pair deletion in exon 10 of the E1α gene [PDF]

, 2017
Benelli, Chantal, Desguerre, Isabelle, Fouque, Françoise, Haenggell, Charles, Liebaers, Inge, Lissens, Willy, Marsac, Cécile, Meirleir, Linda De, Ponsot, Gérard, Seneca, Sara   +9 more
core  

Mitochondrial proteome landscape unveils key insights into melanoma severity and treatment strategies

Cancer, Volume 131, Issue 13, 1 July 2025.
This study uses comprehensive quantitative proteomics of 151 melanoma‐related samples to demonstrate that the upregulation of mitochondrial translation and oxidative phosphorylation is intricately linked to tumor aggressiveness, treatment resistance, and poor clinical outcomes.
Yonghyo Kim, Viktória Doma, Uğur Çakır, Magdalena Kuras, Lazaro Hiram Betancourt, Indira Pla, Aniel Sanchez, Yutaka Sugihara, Roger Appelqvist, Henriett Oskolas, Boram Lee, Jéssica Guedes, Gustavo Monnerat, Gabriel Reis Alves Carneiro, Fábio C. S. Nogueira, Gilberto B. Domont, Johan Malm, Bo Baldetorp, Elisabet Wieslander, István Balázs Németh, A. Marcell Szász, Runyu Hong, Krzysztof Pawłowski, Melinda Rezeli, Ho Jeong Kwon, Jozsef Timar, David Fenyö, Sarolta Kárpáti, György Marko‐Varga, Jeovanis Gil   +29 more
wiley   +1 more source

Oxidant-Based Cytotoxic Agents During Aging: From Disturbed Energy Metabolism to Chronic Inflammation and Disease Progression. [PDF]

Biomolecules
Arnhold J.
europepmc   +1 more source

Decoding the pancreatic cancer microenvironment: The multifaceted regulation of microRNAs

Clinical and Translational Medicine, Volume 15, Issue 7, July 2025.
miRNAs play multiple roles in the tumour microenvironment of pancreatic cancer, including angiogenesis, interactions with cancer‐associated fibroblasts, the immune microenvironment, exosome communication, the neural microenvironment and metabolic reprogramming.
Jie Ji, Dandan Jin, Junpeng Zhao, Xudong Xie, Yujie Jiao, Xuyang He, Yuxuan Huang, Lirong Zhou, Mingbing Xiao, Xiaolei Cao   +9 more
wiley   +1 more source

The neglected PCK1/glucagon (inter)action in nutrient homeostasis beyond gluconeogenesis: Disease pathogenesis and treatment. [PDF]

Mol Metab
Bertinat R, Holyoak T, Gatica R, Jara N, González-Chavarría I, Westermeier F.   +5 more
europepmc   +1 more source

Itaconate suppresses neonatal intestinal inflammation via metabolic reprogramming of M1 macrophage

Clinical and Translational Medicine, Volume 15, Issue 7, July 2025.
Itaconate alleviates NEC by reprogramming M1 macrophage metabolism. ACOD1 deficiency exacerbates NEC severity. 4OI maintains intestinal barrier integrity. 4OI rescues NEC by regulating macrophage mitochondrial activity. Abstract Background Necrotizing enterocolitis (NEC) is a rapidly progressive and severe gastrointestinal disorder in neonates that is ...
Shuchen Huangfu, Chaoting Lan, Sitao Li, Huijuan Wang, Chun Yan, Yuling Yang, Bowen Tian, Yide Mu, Peizhi Zhao, Yan Tian, Yijia Wang, Wei Zhong, Limei Zhong, Yongyan Shi, Yufeng Liu   +14 more
wiley   +1 more source

Metabolic Reprogramming in Stromal and Immune Cells in Rheumatoid Arthritis and Osteoarthritis: Therapeutic Possibilities. [PDF]

Eur J Immunol
Henry ÓC, O'Neill LAJ.
europepmc   +1 more source

Alpha‐Lipoic Acid Alleviates Isoflurane‐Induced Cognitive Dysfunction in Juvenile Mice by Activating Peroxisome Proliferator Activated Receptor Gamma Coactivator ‐1 Alpha

Food Frontiers, Volume 6, Issue 4, Page 1954-1971, July 2025.
Alpha‐lipoic acid (ALA) plays a significant role in alleviating isoflurane‐induced cognitive dysfunction in juvenile mice by activating PGC‐1α, which improves mitochondrial function and energy metabolism in astrocytes. As a potent antioxidant, ALA is commonly found in foods like spinach, broccoli, and yeast, and its supplementation may offer ...
Xingkai Zhao, Donglu Wang, Shuai Li, Xueting Zhang, Zhenlei Zhou   +4 more
wiley   +1 more source