Results 171 to 180 of about 40,891 (231)

Recent Advances on the Role of B Vitamins in Cancer Prevention and Progression. [PDF]

open access: yesInt J Mol Sci
Frost Z   +4 more
europepmc   +1 more source

Magnetite Micro/Nanorobots for Efficient Targeted Alleviation of Inflammatory Bowel Disease

open access: yesAdvanced Science, Volume 12, Issue 26, July 10, 2025.
Improved reactive oxygen species scavenging capacities of functionalized micro/nanorobots (MNRs) are useful for the treatment of inflammatory bowel disease (IBD). MNRs can break the harmful bacteria in IBD, thereby eliminating inflammation and restoring the intestinal barrier function.
Ying Feng   +5 more
wiley   +1 more source

Pyruvate dehydrogenase deficiency in a female due to a 4 base pair deletion in exon 10 of the E1α gene [PDF]

open access: yes, 2017
Benelli, Chantal   +9 more
core  

Mitochondrial proteome landscape unveils key insights into melanoma severity and treatment strategies

open access: yesCancer, Volume 131, Issue 13, 1 July 2025.
This study uses comprehensive quantitative proteomics of 151 melanoma‐related samples to demonstrate that the upregulation of mitochondrial translation and oxidative phosphorylation is intricately linked to tumor aggressiveness, treatment resistance, and poor clinical outcomes.
Yonghyo Kim   +29 more
wiley   +1 more source

Decoding the pancreatic cancer microenvironment: The multifaceted regulation of microRNAs

open access: yesClinical and Translational Medicine, Volume 15, Issue 7, July 2025.
miRNAs play multiple roles in the tumour microenvironment of pancreatic cancer, including angiogenesis, interactions with cancer‐associated fibroblasts, the immune microenvironment, exosome communication, the neural microenvironment and metabolic reprogramming.
Jie Ji   +9 more
wiley   +1 more source

Itaconate suppresses neonatal intestinal inflammation via metabolic reprogramming of M1 macrophage

open access: yesClinical and Translational Medicine, Volume 15, Issue 7, July 2025.
Itaconate alleviates NEC by reprogramming M1 macrophage metabolism. ACOD1 deficiency exacerbates NEC severity. 4OI maintains intestinal barrier integrity. 4OI rescues NEC by regulating macrophage mitochondrial activity. Abstract Background Necrotizing enterocolitis (NEC) is a rapidly progressive and severe gastrointestinal disorder in neonates that is ...
Shuchen Huangfu   +14 more
wiley   +1 more source

Alpha‐Lipoic Acid Alleviates Isoflurane‐Induced Cognitive Dysfunction in Juvenile Mice by Activating Peroxisome Proliferator Activated Receptor Gamma Coactivator ‐1 Alpha

open access: yesFood Frontiers, Volume 6, Issue 4, Page 1954-1971, July 2025.
Alpha‐lipoic acid (ALA) plays a significant role in alleviating isoflurane‐induced cognitive dysfunction in juvenile mice by activating PGC‐1α, which improves mitochondrial function and energy metabolism in astrocytes. As a potent antioxidant, ALA is commonly found in foods like spinach, broccoli, and yeast, and its supplementation may offer ...
Xingkai Zhao   +4 more
wiley   +1 more source

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