Results 251 to 260 of about 68,490 (304)
Plant, Cell &Environment, Volume 48, Issue 8, Page 6373-6396, August 2025.ABSTRACT Communication between the diverse compartments of plant cells relies on an intricate network of molecular interactions that orchestrate organellar development and adaptation to environmental conditions. Plastid‐to‐nucleus signalling pathways play a key role in relaying information from developing, mature, and damaged or disintegrating ...
Dario Di Silvestre +14 more
wiley +1 more source
The FASEB Journal, Volume 39, Issue 13, 15 July 2025.Here, we report that mitochondria from rat skeletal muscle contain a select population of nuclear‐encoded protein‐coding and noncoding RNAs, including 3 microRNAs whose expression tended to be altered by exercise training. These findings suggest that mitochondria‐localized nuclear‐encoded RNAs may play a role in mediating the beneficial adaptive ...
Jessica L. Silver +8 more
wiley +1 more source
Lipophilic Resazurin in Bioelectrochemical Systems: Role in Regulating Carbon Metabolic Pathways
ChemElectroChem, Volume 12, Issue 14, July 10, 2025.This study clarifies the mechanism by which lipophilic shuttles regulate carbon metabolism in Shewanella. Lipophilic electron shuttles, such as resazurin, permeate into the periplasm to mediate extracellular electron transfer, thereby altering the redox potential sensed by inner‐membrane quinones and consequently activating the NADH‐dependent metabolic
Siyu Tan +8 more
wiley +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, Volume 599, Issue 13, Page 1821-1851, July 2025.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Advanced Therapeutics, Volume 8, Issue 7, July 2025.Hispidulin disrupts the KITENIN/ErbB4 oncogenic complex and inhibits KITENIN‐mediated AP‐1 activity, cell invasion, and aerobic glycolysis. It also suppresses the production of cancer‐associated metabolites and downregulates transcriptional regulators downstream of the KITENIN complex.
Mücahit Varlı +7 more
wiley +1 more source
FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity
Advanced Science, Volume 12, Issue 25, July 3, 2025.Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li +11 more
wiley +1 more source
Advanced Science, Volume 12, Issue 26, July 10, 2025.Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan +16 more
wiley +1 more source
Advanced Science, Volume 12, Issue 26, July 10, 2025.Gut metabolite trimethylamine N‐oxide accumulates in the diabetic wound area to amplify macrophage inflammation via enhancing glycolysis activities. Kinsenoside induces macrophage repolarization from M1 to M2 phenotype through inhibiting IRE1α/XBP1 pathway, followed by HIF‐1α‐glycolysis axis repression and mitophagy‐oxidative phosphorylation axis ...
Li Lu +13 more
wiley +1 more source