Results 251 to 260 of about 181,145 (327)

How Plants May Maintain Protein Homeostasis Under Rising Atmospheric CO2

Plant, Cell &Environment, EarlyView.
ABSTRACT Vascular plants may employ several physiological mechanisms to stabilize their protein contents as atmospheric CO2 concentrations change over a day, year, decade, or century. One mechanism is that plants may rely more on soil ammonium as their nitrogen source when CO2 increases.
Arnold J. Bloom, Xiaoxiao Shi, Nathan M. Hannon   +2 more
wiley   +1 more source

Targeting pyruvate dehydrogenase kinase 1 overcomes EGFR C797S mutation-driven osimertinib resistance in non-small cell lung cancer. [PDF]

Exp Mol Med
Park W, Wei S, Xie CL, Han JH, Kim BS, Kim B, Jin JS, Yang ES, Cho MK, Ryu D, Yang HX, Bae SJ, Ha KT.   +12 more
europepmc   +1 more source

Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next

Photochemistry and Photobiology, EarlyView.
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal, Durdana Muntaqua, Gagan Chhabra, Nihal Ahmad   +3 more
wiley   +1 more source

Pyruvate dehydrogenase kinase 4 deficiency attenuates cisplatin-induced acute kidney injury.

Kidney International, 2017
C. J. Oh, Chae-Myeong Ha, Young-Keun Choi, Sungmi Park, M. Choe, N. Jeoung, Y. Huh, Hyo-Jeong Kim, H. Kweon, Ji-Min Lee, S. Lee, Jae-Han Jeon, Robert A. Harris, K. Park, In-kyu Lee   +14 more
semanticscholar   +1 more source

[Pyruvate Dehydrogenase [Lipoamide]] Kinase Isozyme 1, Mitochondrial [PDF]

, 2020
openaire   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Pyruvate Dehydrogenase Kinase 4 Deficiency Results in Expedited Cellular Proliferation through E2F1-Mediated Increase of Cyclins

Molecular Pharmacology, 2017
John Choiniere, Jianguo Wu, Li Wang
semanticscholar   +1 more source

[Pyruvate Dehydrogenase [Lipoamide]] Kinase Isozyme 4, Mitochondrial [PDF]

, 2020
openaire   +1 more source

Modelling the effect of varying metabolic rate and cardiac output on estimated tissue and blood O2 and CO2 levels in an extreme deep‐diver, the goose‐beaked whale (Ziphius cavirostris)

Experimental Physiology, EarlyView.
Abstract High‐resolution movement data from Cuvier's beaked, or goose‐beaked whale (Ziphius cavirostris, hereafter Ziphius, n = 8) tag deployments (4.1–19.2 days) were used to estimate blood and tissue O2 and CO2 levels. Acceleration and magnetometry data were used to estimate the locomotion cost (LC) from the relationship between activity and the O2 ...
Andreas Fahlman, Gregory S. Schorr, David A. Sweeney, Brenda K. Rone, Shannon N. Coates, Austin S. Allen, Lucia M. Martín López, Susan M. Jarvis, Erin A. Falcone   +8 more
wiley   +1 more source

Antenatal betamethasone impairs markers of cardiac development and function in near‐term lambs

Experimental Physiology, EarlyView.
Abstract figure Summary of key molecular differences in the left ventricle of near‐term lambs exposed to antenatal betamethasone, compared to saline. Pregnant ewes received two doses of either saline (Saline) or betamethasone (Betamethasone, intramuscular, 11.4 mg) given 24 h apart, before delivery at 140 days of gestation (dG, term = 150 dG).
Reza Amanollahi, Ashley S. Meakin, Stacey L. Holman, Vicki L. Clifton, Kent L. Thornburg, Michael D. Wiese, Kathryn L. Gatford, Mitchell C. Lock, Janna L. Morrison   +8 more
wiley   +1 more source