Results 131 to 140 of about 128,438 (311)
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease
Hepatology, EarlyView., 2022 RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso +16 more
wiley +1 more source
Anion effects on pyruvate kinase (Short Communication) [PDF]
, 1974 Peggy Jo Taylor, James L. Robinson
openalex +1 more source
Angewandte Chemie, EarlyView.Pseudouridin‐5'‐triphosphat (ΨTP) und sein N1‐methyliertes Derivat (m1ΨTP) sind entscheidende Komponenten in der mRNA‐Impfstofftechnologie. Hier wird ein atomökonomischer, ertragreicher biokatalytischer Weg zur Synthese von ΨTP vorgestellt. Zudem wurde ein neuer chemo‐enzymatischer Weg für die m1ΨTP‐Synthese entwickelt.
Martin Pfeiffer +4 more
wiley +1 more source
Imaging‐Based High‐Content Screening with Clickable Probes Identifies XPB Inhibitors
Angewandte Chemie International Edition, Accepted Article.High‐content screening (HCS) has become a powerful tool in drug discovery; however, its reliance on indirect readouts and surrogate markers limits HCS’s ability to directly assess drug‐protein interactions at endogenous levels, particularly in subcellular contexts.
Shuqi Li +10 more
wiley +1 more source
Pyruvate Kinase, a Possible Regulatory Enzyme in Higher Plants [PDF]
, 1973 Ronald G. Duggleby, David T. Dennis
openalex +1 more source
Angewandte Chemie International Edition, EarlyView.Pseudouridine‐5′‐triphosphate (ΨTP) and its N1‐methylated derivative (m1ΨTP) are crucial components in mRNA vaccine technology. Here, an atom‐economic, high‐yielding biocatalytic route for ΨTP synthesis is presented. A new chemoenzymatic route for m1ΨTP synthesis was developed.
Martin Pfeiffer +4 more
wiley +1 more source
Comparison of the properties of two forms of pyruvate kinase in rat liver and determination of their separate activities during development [PDF]
, 1972 Marshall C. Middleton, Deryck G. Walker
openalex +1 more source
American Journal of Hematology, EarlyView.
María‐Angustias Molina‐Arrebola +1 more
wiley +1 more source
Animal Research and One Health, EarlyView.Multi‐omics analysis revealed that FOS supplementation increased the abundance of Phascolarctobacterium, GCA‐900066575, Shuttleworthia, Olsenella, Eubacterium_hallii_group while decreasing Alistipes. It also influenced the metabolism of S‐lactoylglutathione, p‐cresol glucuronate, 2‐phenylethanol glucuronide, propionic acid, dulcitol, and inhibited the ...
Dan Song +11 more
wiley +1 more source