Results 171 to 180 of about 237,828 (335)
Advanced Science, EarlyView.The lamina joint determines leaf angle and plant architecture. Xu et al. establish a live‐imaging system for the rice lamina joint and reveal that asymmetric epidermal cell elongation and division between the lateral and medial edges drive leaf angle formation.
Yiru Xu +9 more
wiley +1 more source
Phosphorylation is switch of L-type pyruvate kinase allostery [PDF]
, 2010 Ilona Faustova +4 more
openalex +1 more source
Advanced Science, EarlyView.Glutathione (GSH) defines oxidative balance, but can it directly tune central metabolism? The research reveals that GSH binds and potently activates pyruvate kniase M2 (PKM2), rewiring glycolysis and dictating ferroptosis sensitivity. Combining GSH depletion with PKM2 activation triggers mitochondrial damage and lipid peroxidation, profoundly ...
Tsan‐Jan Chen +17 more
wiley +1 more source
Advanced Science, EarlyView.This review introduces the development and classification of all‐nanozyme cascade reaction systems, highlighting mechanistic insights and research methods for understanding catalytic features and design principles. It provides detailed classifications, surveys recent applications in biosensing and therapy, and discusses the challenges that all‐nanozyme
Caixia Zhu +4 more
wiley +1 more source
Advanced Science, EarlyView.This study demonstrates a cuproptosis mechanism involving nicotinamide adenine dinucleotide (NADH)‐reductive stress in neural cells. Copper activates dihydrolipoamide dehydrogenase under mitochondrial pH, accumulating NADH. Copper also induces mitochondrial permeability transition pore opening, facilitating NADH translocation to the cytosol and ...
Si‐Yi Zhang +3 more
wiley +1 more source
Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs OXPHOS and prostate cancer metastatic spread [PDF]
, 2015 Elisa Giannoni +10 more
openalex +1 more source
Animal Models and Experimental Medicine, EarlyView.Vitamin D, traditionally known to promote calcium and bone health, is being explored for its role in cancer prevention and treatment through its influence on cell proliferation, differentiation, apoptosis, and immune response. The vitamin D receptor (VDR) regulates gene expression and interacts with key signaling pathways such as Wnt/β‐catenin, MAPK ...
D. Prasanth +10 more
wiley +1 more source
Studies on the Enolization of Pyruvate by Pyruvate Kinase
Journal of Biological Chemistry, 1960 openaire +2 more sources