Results 221 to 230 of about 237,828 (335)

Malate targets pyruvate kinase M2 to promote colorectal cancer cell cycle arrest and tumor suppression. [PDF]

Mol Biomed
Zhao K, Zhang F, Qin Q, Zhang D, Yang F, Huang Y, Deng R, Jing H, Xiao W, Miao H, Shi R.   +10 more
europepmc   +1 more source

LY294002 inhibits the Warburg effect in gastric cancer cells by downregulating pyruvate kinase M2

, 2018
Jian Lü, Min Chen, Sumeng Gao, Jigang Yuan, Zhu Zhu, Xiaoping Zou   +5 more
openalex   +2 more sources

Roles of Liquid Interface with Delicate Nanoarchitectonics for Molecular Recognition, Analysis, Reaction, Molecular Machine, Microrobot, and Life

ChemNanoMat, EarlyView.
This review paper willdiscuss nanoarchitectonics at liquid interfaces. Topics covered will include molecular recognition, analytical methods, reactions controlled at liquid interfaces, control of molecular machines and microrobots, and regulation of biological phenomena using liquid interfaces. Overall, all of these processes require extremely delicate
Katsuhiko Ariga
wiley   +1 more source

Pyruvate Kinase Deficiency: Markedly Decreased Reticulocyte PK Activity and Limited Specificity of the PK/HK Ratio. [PDF]

Int J Mol Sci
Koleva L, Dolgikh IA, Kryukova AV, Prudinnik DS, Bovt EA, Shakhidzhanov SS, Mann SG, Smetanina NS, Ataullakhanov FI, Sinauridze EI.   +9 more
europepmc   +1 more source

Psychometric validation of the Pyruvate Kinase Deficiency Diary and Pyruvate Kinase Deficiency Impact Assessment in adults in the phase 3 ACTIVATE trial. [PDF]

J Patient Rep Outcomes, 2023
Andrae DA, Grace RF, Jewett A, Foster B, Klaassen RJ, Salek S, Li J, Tai F, Boscoe AN, Zagadailov E.   +9 more
europepmc   +1 more source

Inhibiting pyruvate kinase muscle isoform 2 regresses group 2 pulmonary hypertension induced by supra‐coronary aortic banding

, 2022
Ping Yu Xiong, Mehras Motamed, Kuang‐Hueih Chen, Asish Dasgupta, François Potus, Lian Tian, Ashley Martin, Jeffrey Mewburn, Oliver W. Jones, Arthur Thébaud, Stephen L. Archer   +10 more
openalex   +2 more sources

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals

Clinical Pharmacology &Therapeutics, EarlyView.
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan, Lynn Miller, Sam Wade, Jenni Ilomäki, Dickson Lukose, Jia Rong, Geoffrey I. Webb   +6 more
wiley   +1 more source

Transcriptomic analysis reveals that pyruvate kinase potentially plays a key role in the differentiation of Spirometra mansoni proglottids by regulating the glycolysis pathway. [PDF]

PLoS Negl Trop Dis
Zhou K, Cao CY, Ru SS, Wang RJ, Hao J, Zhang X.   +5 more
europepmc   +1 more source

Partial purification and characterization of pyruvate kinase from human erythrocytes /

, 1968
D.F. Calbreath
openalex   +1 more source

Allosteric pyruvate kinase-based “logic gate” synergistically senses energy and sugar levels in Mycobacterium tuberculosis [PDF]

, 2017
Wenhe Zhong, Cui Liang, Boon Chong Goh, Qixu Cai, Peiying Ho, Yok Hian Chionh, Meng Yuan, Abbas El Sahili, Linda A. Fothergill‐Gilmore, Malcolm D. Walkinshaw, Julien Lescar, Peter C. Dedon   +11 more
openalex   +1 more source