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2021
Pyruvate kinase is an important enzyme of glycolytic pathway that catalyzes the last step of this pathway. In human erythrocytes, there is no mitochondrion hence glycolytic pathway is the most important source of energy generation. In vitro, in vivo, and case control studies suggested that pyruvate kinase deficiency provides resistance against P ...
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Pyruvate kinase is an important enzyme of glycolytic pathway that catalyzes the last step of this pathway. In human erythrocytes, there is no mitochondrion hence glycolytic pathway is the most important source of energy generation. In vitro, in vivo, and case control studies suggested that pyruvate kinase deficiency provides resistance against P ...
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1973
Publisher Summary This chapter describes pyruvate kinase. The enzyme has a number of attributes that make it of particular interest to various investigators. It was the first and perhaps the most clearly apparent example of an enzyme with an absolute requirement for a monovalent cation for its catalytic activity.
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Publisher Summary This chapter describes pyruvate kinase. The enzyme has a number of attributes that make it of particular interest to various investigators. It was the first and perhaps the most clearly apparent example of an enzyme with an absolute requirement for a monovalent cation for its catalytic activity.
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1987
Publisher Summary The chapter discusses the regulatory phosphorylation of pyruvate kinase type L by cAMP-dependent protein kinase. It also briefly discusses the role of phosphorylation of liver pyruvate kinase in the regulation of glycolysis and gluconeogenesis.
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Publisher Summary The chapter discusses the regulatory phosphorylation of pyruvate kinase type L by cAMP-dependent protein kinase. It also briefly discusses the role of phosphorylation of liver pyruvate kinase in the regulation of glycolysis and gluconeogenesis.
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1978
Hereditary nonspherocytic hemolytic anemia is a relatively recently recognized entity. It was first discussed in detail by Dacie et al, in 1953,1 and by 1960 over 60 cases had been reported.2 Motulsky et al.3 noted increased 2,3-DPG levels in several patients with hereditary nonspherocytic hemolytic anemia.
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Hereditary nonspherocytic hemolytic anemia is a relatively recently recognized entity. It was first discussed in detail by Dacie et al, in 1953,1 and by 1960 over 60 cases had been reported.2 Motulsky et al.3 noted increased 2,3-DPG levels in several patients with hereditary nonspherocytic hemolytic anemia.
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