Results 161 to 170 of about 51,864 (248)

Cardiorespiratory and Hematological Responses to High‐Intensity Interval Training in Adolescent Girls With Overweight or Obesity: A Randomized Controlled Trial

open access: yesEuropean Journal of Sport Science, Volume 26, Issue 5, May 2026.
ABSTRACT This randomized controlled trial examined the effects of a 10‐week high‐intensity interval training (HIIT) program on physiological and hematological outcomes in 28 adolescent girls with overweight or obesity. Participants were randomly assigned to a HIIT group or a control group. The HIIT protocol comprised 4 sets of 6 × 15‐s bouts at 90%–105%
Wissal Abassi   +6 more
wiley   +1 more source

Pyruvate kinase M2 isozyme (PKM2) [PDF]

open access: yesScience-Business eXchange, 2008
openaire   +1 more source

Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang   +6 more
wiley   +1 more source

Liver Fibrosis: Molecular Pathogenesis and Therapeutic Interventions

open access: yesMedComm, Volume 7, Issue 5, May 2026.
We systematically summarized the etiologies, diagnostic approaches, and pathogenic mechanisms of liver fibrosis. Also, the therapeutic interventions for liver fibrosis were systematically classified into two main categories: etiological treatment and mechanism‐based antifibrotic therapies.
Jiaorong Qu   +8 more
wiley   +1 more source

Ferrocene‐Based Sensors for Green Analytical Applications in Environmental, Biomedical, Industrial, and Food Monitoring

open access: yesChemistryOpen, Volume 15, Issue 5, May 2026.
Ferrocene derivatives represent a transformative class of molecular sensors, combining exceptional electrochemical stability with tunable redox characteristics that enable precise detection across diverse analytical challenges in environmental, medical, and industrial applications.
Ala'a Al‐Akhras   +6 more
wiley   +1 more source

Development of [18F]DASA-10 for enhanced imaging of pyruvate kinase M2. [PDF]

open access: yesNucl Med Biol, 2023
Kendirli MT   +10 more
europepmc   +1 more source

The Arsenal of Aromatic Degrading Bacteria: How They Sense, Chase, Adapt and Destroy Environmental Pollutants

open access: yesMicrobial Biotechnology, Volume 19, Issue 5, May 2026.
In the environment, bacteria sense aromatic pollutants, migrate toward them, adapt to toxicity, and deploy specialized uptake and catabolic systems. Genomic plasticity, metabolic versatility and division of labor within populations together aid in the degradation of persistent aromatics, highlights that biodegradation is driven by various eco ...
Prashant S. Phale   +2 more
wiley   +1 more source

Glucose Metabolism Regulating Colorectal Cancer Initiation and Progression

open access: yesCancer Science, Volume 117, Issue 5, Page 1199-1208, May 2026.
Drugs and compounds targeting glycolysis in CRC and the mechanisms by which these drugs inhibit their respective targets. ABSTRACT Colorectal cancer (CRC) is one of the most common types of invasive cancer worldwide, which has the characteristics of poor curative effect and poor prognosis. Increasing evidence suggests that hyperactivated glucose uptake
Meiyi Lin, Junpeng Cui
wiley   +1 more source

Defining the tumor microenvironment of non‐small cell lung cancer

open access: yesImmunology &Cell Biology, Volume 104, Issue 5, Page 499-518, May‐June 2026.
The tumor microenvironment (TME) in non‐small cell lung cancer is highly heterogeneous, both at a patient level and tumor microenvironment resolution. Defining the tumor microenvironment from patient‐responders and non‐responders will aid in the development of targeted therapeutics specific for each individual patient.
Kidane Siele Embaye   +5 more
wiley   +1 more source

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