Optical genome mapping detects cryptic high‐risk and targetable abnormalities in adult AML
British Journal of Haematology, EarlyView.Summary Acute myeloid leukaemia (AML) risk stratification relies on cytogenetic and molecular abnormalities defined by European LeukemiaNet (ELN) 2022. Conventional cytogenetic techniques, including chromosomal banding analysis (CBA) and fluorescence in situ hybridization, have limited resolution and may miss cryptic events. Optical genome mapping (OGM)
Audrey Bidet +10 more
wiley +1 more source
Guideline of guidelines: Peyronie's disease
BJU International, EarlyView.Objective To compare major Peyronie's disease (PD) guidelines, highlight key similarities and differences among panel recommendations, and identify areas requiring further research. Methods An extensive review was conducted to analyse and compare diagnostic and treatment recommendations from publicly available guidelines published by the American ...
Francesco Chierigo +7 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley +1 more source
Global Warming and Mass Extinctions Associated With Large Igneous Province Volcanism
Geophysical Monograph Series, Page 83-102., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
David P. G. Bond, Yadong Sun
wiley +1 more source
Cell Proliferation, EarlyView.This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang +10 more
wiley +1 more source
European Journal of Dental Education, EarlyView.ABSTRACT Introduction CAD/CAM (Computer‐Aided Design/Computer‐Aided Manufacturing) technology has become integral to modern dental practice, requiring structured integration into dental education. However, little is known about how well dental students in Croatia understand and engage with these technologies.
Sanja Peršić Kiršić +3 more
wiley +1 more source
Fisheries Management and Ecology, EarlyView.ABSTRACT Local ecological knowledge can be useful to assess data‐limited fisheries such as the Ontario Black Bass (Micropterus spp.) recreational fishery. We surveyed local anglers using the Life History Calendar approach to determine if there were perceived changes in fishing quality for Black Bass in eastern Ontario across different time periods. For
Joel Zhang +8 more
wiley +1 more source
Effects of varying concentrations of Ubiquinol (coenzyme Q10) on physiological parameters in male donkeys (<i>Equus asinus</i>). [PDF]
Front Vet SciAkhtar MF, Umar M, Changfa W.
europepmc +1 more source
Fisheries Oceanography, EarlyView.ABSTRACT Yellowfin sole (Limanda aspera) support the largest flatfish fishery in the world and contribute substantially to the eastern Bering Sea (EBS) flatfish catch. The EBS has been warming and acidifying, trends that are expected to intensify into the future.
Emily Slesinger +5 more
wiley +1 more source
Higher Redox State of Coenzyme Q10 Is Associated with Higher Risk of All-Cause Mortality in a Sample from the Northern German General Population. [PDF]
Antioxidants (Basel)Stürmer P +7 more
europepmc +1 more source