Results 11 to 20 of about 7,675 (163)
Establishment of a humanized SCA2 mouse model carrying a CAA disruption preventing CAG repeat expansion in pathogenic genes. [PDF]
Animal Model Exp MedIn this study, we established a mouse model in which CAG repeats do not undergo microsatellite instability (MSI) across generations. A humanized ATXN2 cDNA with four CAA interruptions within 73 CAG expansions was inserted into the Rosa26 locus of C57BL/6J mice. At the same time, a 23 CAG control mouse model was also generated.
Zhang Y +9 more
europepmc +2 more sources
Barriers to Changing Sedation Practice for Patients Undergoing Mechanical Ventilation on the Intensive Care Unit: A Qualitative Interview Study of Clinical Staff. [PDF]
Nurs Crit CareABSTRACT Background Medical sedation is a requirement for mechanical ventilation for most patients admitted to the intensive care unit (ICU). Sedation can help minimise patient discomfort, pain and distress, but can lead to hypotension, bradycardia, prolonged ventilation and delirium.
Richards ND, Bekker HL, Howell SJ.
europepmc +2 more sources
Innovation and Green Development, 2023 This research mainly investigates the impact of digital transformation on corporate financialization and which type of digital technology influences such financialization by utilizing data of listed companies from 2010 to 2020.
Bo Sui, Liuyang Yao
doaj +1 more source
British Journal of Psychology, Volume 114, Issue 4, Page 945-968, November 2023., 2023 Abstract We investigated the relationship between ambient temperature and prosocial behaviour in real‐life settings. It was guided by two mechanisms of opposite predictions, namely (1) higher temperatures decrease prosociality by harming well‐being, and (2) higher temperatures increase prosociality by promoting the embodied cognition of social warmth ...
Henry Kin Shing Ng, Sing‐Hang Cheung
wiley +1 more source
Voluntary carbon market derivatives: Growth, innovation & usage
Borsa Istanbul Review, 2022 Voluntary carbon markets (VCMs) have emerged as a preferred market mechanism to support the global economy's transition to a low carbon future. Trading in carbon offset derivatives has moved into the financial mainstream with commodity exchanges now ...
Gregor Spilker, Nick Nugent
doaj +1 more source
Workplace support for newly qualified doctors and secondary school teachers: A comparative analysis
British Educational Research Journal, Volume 49, Issue 5, Page 1005-1043, October 2023., 2023 Abstract Doctors and teachers in their first year of practice face steep learning curves and increased stress, which can induce poor mental health, burnout and attrition. Informal workplace support from colleagues can help smooth transitions and aid professional development.
Helen Foster‐Collins +2 more
wiley +1 more source
Protein Science, Volume 32, Issue 9, September 2023., 2023 Abstract Intrinsically disordered proteins (IDPs) are often multifunctional and frequently posttranslationally modified. Deleted in split hand/split foot 1 (Dss1—Sem1 in budding yeast) is a highly multifunctional IDP associated with a range of protein complexes. However, it remains unknown if the different functions relate to different modified states.
Nina L. Jacobsen +8 more
wiley +1 more source
Evaluating the Effect of Gender on Nursing Students' Attitudes Toward Violence Against Women by Metaphor Analysis: A Qualitative Study. [PDF]
Public Health NursABSTRACT Objective The objective of this study is to evaluate the effect of gender on nursing students' attitudes toward violence against women using metaphor analysis. Methods The study was conducted with 64 nursing students from January to April of 2023. Metaphor analysis was used as a research method.
Delimehmet E, Bahadır Yılmaz E.
europepmc +2 more sources
Journal of School Health, Volume 93, Issue 6, Page 450-463, June 2023., 2023 ABSTRACT BACKGROUND Implementation of Health Promoting School (HPS) programs can be challenging due to the dynamic school context. Navigating between program fidelity and adaptation, as well as integrating the program, is essential for successful implementation, and consequently, for program effects.
Gerjanne Vennegoor +5 more
wiley +1 more source
Economic policy uncertainty and renewable energy innovation: International evidence
Innovation and Green Development, 2022 This research investigates the impact of economic policy uncertainty on renewable energy innovation, based on a panel of 22 countries during the period 1985–2019. The results indicate that economic policy uncertainty exerts a positive effect on renewable
Gen-Fu Feng, Mingbo Zheng
doaj +1 more source