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Variation in interferon-γ production between QFT-Plus and QFT-GIT assays in TB contact investigation
Respiratory Investigation, 2019Individuals with recent contact with active tuberculosis (TB) patients were screened for latent tuberculosis infection (LTBI) considering their greater relative risk for developing active TB. QuantiFERON®-TB Gold Plus (QFT-Plus) assay offers two TB-specific antigen tubes (TB1 and TB2). TB2 is designed to elicit both CD4 and CD8 T-cell responses.
Hidetoshi Igari
exaly +3 more sources
Medical Microbiology and Immunology, 2019
The new QuantiFERON-TB Gold Plus employs modified peptides optimized to elicit an IFNγ response from CD8+ cytotoxic T lymphocytes in addition to CD4+ T cells. With a view to improve the difficult identification of TB cases, we assessed the combination of two specific immunological markers comprising IFNγ secretion and T cells co-expression of CD25 and ...
Ilaria Sauzullo +2 more
exaly +3 more sources
The new QuantiFERON-TB Gold Plus employs modified peptides optimized to elicit an IFNγ response from CD8+ cytotoxic T lymphocytes in addition to CD4+ T cells. With a view to improve the difficult identification of TB cases, we assessed the combination of two specific immunological markers comprising IFNγ secretion and T cells co-expression of CD25 and ...
Ilaria Sauzullo +2 more
exaly +3 more sources
Evaluation of QFT-Plus performance using blood samples stored at room temperature
International Journal of Tuberculosis and Lung Disease, 2021Yoshifumi Oda, H Mukae
exaly +3 more sources
American Journal of Respiratory and Critical Care Medicine
Abstract Introduction: Children exhibit heightened susceptibility to tuberculosis (TB), a disease caused by Mycobacterium tuberculosis (MTB) infection. Among the interferon-gamma release assays (IGRAs) recommended by the World Health Organization (WHO) for MTB infection screening is the newly included QuantiFERON-TB Gold Plus (QFT ...
H. Chen, C. Shen, D. Li
openaire +1 more source
Abstract Introduction: Children exhibit heightened susceptibility to tuberculosis (TB), a disease caused by Mycobacterium tuberculosis (MTB) infection. Among the interferon-gamma release assays (IGRAs) recommended by the World Health Organization (WHO) for MTB infection screening is the newly included QuantiFERON-TB Gold Plus (QFT ...
H. Chen, C. Shen, D. Li
openaire +1 more source

