Results 111 to 120 of about 1,108,829 (262)

Mitochondrial SLC25A46 Rewires Fatty Acid Oxidation to Promote Cell Proliferation and Ferroptosis Evasion in Ovarian Cancer by Stabilizing CACT

Advanced Science, EarlyView.
Mitochondrial SLC25A46 is upregulated in ovarian cancer (OC) and correlates with poor prognosis. SLC25A46 stabilizes CACT to activate fatty acid oxidation, increasing ATP and NADPH production to drive cell proliferation and ferroptosis evasion. SLC25A46 silencing sensitizes OC cells to ferroptosis and carboplatin, offering a promising therapeutic ...
Yunge Gao, Jiatao Hao, Xiaohong Zhang, Meiting Long, Yujing Feng, Xiaoyue Liu, Xuejian Li, Shujuan Liu, Xin Guo, Xiaohui Lv   +9 more
wiley   +1 more source

The impact of Rhamnolipid on the Physiological characteristics and metabolic pathways of Potato

Scientia Horticulturae
The potato serves as a crucial food crop and a significant industrial and economic mainstay in Qinghai. The impact of rhamnolipid, a typical biological fertilizer, on potato yield in Qinghai requires further investigation.
Chenxu Gao, Shuqun Deng, Dong Zhao, Junlong Feng, Jiali Ning, Zhuofei Zhang, Weiying Zhang, Haimei An, Shuo Shen, Hongyu Chen, Yang Zhang, Wei Li   +11 more
doaj   +1 more source

qRT-PCR analysis of MALAT-1 expression in transfected ovarian cells.

, 2016
(A) qRT-PCR analysis of MALAT-1 expression following shRNA knockdown. OVCAR3 cells were grown and transfected with four different MALAT-1 shRNA vectors (shM1 to shM4) and then subjected to qRT-PCR analysis.
Xiaying Xu (3166854), Xiujie Sheng (3166839), Huabing Lv (3166845), Qirong Wen (3166848), Linyu Tan (3166851), Jianqi Li (43568), Juan Li (146180), Yanqing Zhou (3166842)   +7 more
core   +1 more source

Vascularized Liver‐on‐a‐Microsphere Reveals Alanine‐Glucose Metabolism‐Driven Regulation of Liver Function and Injury

Advanced Science, EarlyView.
A vascularized liver‐on‐a‐microsphere system is developed to recreate lobule‐like cellular organization and endothelial barrier function within compartmentalized hydrogel particles. The platform enhances hepatic performance and reveals alanine‐glucose cycle activation linked to improved detoxification capacity, offering a high‐throughput microscale ...
Jingyang Li, Zengnan Wu, Yingrui Zhang, Shulang Chen, Yongning Lin, Shiyu Chen, Tong Xu, Xianli Meng, Yi Zhang, Jin‐Ming Lin   +9 more
wiley   +1 more source

qRT-PCR validation of the RNA-Seq result.

, 2019
A). Nine genes, including 7 differentially expressed and 2 aging-related genes, were validated by qRT-PCR. RNA-Seq gene expression calculated by fold-change in I178 (B) and X178 (C).
Stefan Hey (7846829), Hongwei Zhang (28335), Feng Wang (44414), Jianhua Wang (159545), Xuhui Li (4224337), Yixuan Peng (7846826), Guoying Wang (159551), Riliang Gu (7513292), Li Li (14993)   +8 more
core   +1 more source

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

qRT-PCR with saliva samples

BioTechniques, 2012
Kristie Nybo
doaj   +1 more source

qRT-PCR validations results of DEGs in C. Ciliata.

, 2016
a. The fold changes for 9 DEGs (difference between AF vs nymphs and AM vs nymphs) from RPKM value in RNA-Seq data. b. The fold changes of these 9 DEGs in AF, AM and nymphs from qRT-PCR data.
Ningning Fu (3142122), Cheng Qu (3142119), Yihua Xu (398718), Ran Wang (169166), Fengqi Li (3142116), Chen Luo (302288)   +5 more
core   +1 more source

8‐Oxoguanine Modified CircMTUS1 Drives PABPC1 Phase Separation to Promote Gastric Cancer Progression and Cisplatin Resistance via Autophagy

Advanced Science, EarlyView.
ABSTRACT Gastric cancer (GC) is a major global health concern, as its prevention and treatment remain significant challenges. The 8‐oxoguanine (o8G) modification of circRNAs, alongside their capacity to orchestrate liquid‐liquid phase separation (LLPS) and autophagy, plays a pivotal role in driving tumor progression and determining therapeutic outcomes.
Lei Peng, Lurong Li, Zhenghui Zhu, Chenyang Li, Huaiming Sang, Guoxin Zhang, Xuan Li, Yini Dang, Yuanyuan Li   +8 more
wiley   +1 more source