Background. About 60% of deaths from treatable conditions are caused by poor health care, while the remaining deaths result from failure to use the health care system. High-quality health systems can prevent 2.5 million deaths from cardiovascular disease,
Hladkykh F.V.
doaj +1 more source
DEPENDENT PERSON IN SELF-CARE WITH COMORBIDITY, RESULTS SENSITIVE TO REHABILITATION NURSING CARE: SYSTEMATIC REVIEW OF THE LITERATURE [PDF]
Background: Rehabilitation Nursing assumes a fundamental role in contemporary society in the response to the installation of new paradigms of chronic illness and dependence, induced by demographic aging and the advent of a large number of associated ...
António, Lista, César, Fonseca
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
What About the Refugees? Regime Type, Non-Selectorate Actors, and Health Policy [PDF]
In order to tackle the question of refugee health care provision in relation to regime type, a three step approach was taken. First, regime type was shown to significantly influence various public health indicators; democracies increased health care ...
Im, Timothy
core +2 more sources
If you can’t measure it- you can’t change it – a longitudinal study on improving quality of care in hospitals and health centers in rural Kenya [PDF]
Background: The Kenyan Ministry of Health- Department of Standards and Regulations sought to operationalize the Kenya Quality Assurance Model for Health.
Brodowski, Marc +10 more
core +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Mona Haugum,1,2 Hilde Hestad Iversen,1 Jon Helgeland,1 Anne Karin Lindahl,2,3 Oyvind Bjertnaes11Division of Health Services, Norwegian Institute of Public Health, Oslo, Norway; 2Department of Health Management and Health Economics, Institute of Health ...
Haugum M +4 more
doaj
Prospects for comparing European hospitals in terms of quality and safety [PDF]
Purpose. Being able to compare hospitals in terms of quality and safety between countries is important for a number of reasons. For example, the 2011 European Union directive on patients’ rights to cross-border health care places a requirement on all ...
Anderson, J.E. (Janet) +9 more
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source

