Results 171 to 180 of about 265,123 (216)

Pure Gaussian Apodisation Reduces Integral Crosstalk Sensitivity in Quantitative NMR

Magnetic Resonance in Chemistry, EarlyView.
Exponential apodisation redistributes peak area away from its centre, which increases crosstalk with neighbouring peaks and reduces integral trueness when integrating between defined regions. A pure Gaussian apodisation limits wing growth: Crosstalk between peaks is not worsened, and trueness is conserved during integration.
A. Flook, C. S. Raman, G. C. Lloyd‐Jones   +2 more
wiley   +1 more source

Superior transplant recipient outcome prediction and pathology assessment using rapid deep learning applied to procurement kidney biopsies. [PDF]

Sci Rep
Gaut JP, Marsh JN, Chen L, Zhang F, Yu X, Wilson P, Liu TC, Swamidass SJ.   +7 more
europepmc   +1 more source

Alterations in Metabolites Associated With Umbilical Cord Blood in Monozygotic Twins Discordant for Congenital Heart Disease

Pediatric Discovery, EarlyView.
This study found that the metabolomic signature of umbilical venous cord blood in congenital heart disease (CHD) differs from that of healthy monozygotic (MZ) co‐twins. Dysregulation of metabolic pathways like glucose, lipid, and amino acid metabolism, along with altered metabolites, helps understand CHD predisposition.
Fang Xiang, Xiao Yuan, Yi Yang, Philip N. Baker, Mark D. Kilby, Chao Tong, Xi Yuan   +6 more
wiley   +1 more source

Impact of Column Load and Signal-to-Noise Threshold on the Accuracy and Repeatability of Jet A Hydrocarbon Profiling via GC×GC/FID. [PDF]

J Sep Sci
Modereger BA, Caceres-Martinez LE, Peretich ME, Kenttämaa HI, Kilaz G.   +4 more
europepmc   +1 more source

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

PROTEOMICS, EarlyView.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan, Clinton J. Bradfield, Sandhini Saha, Sung Hwan Yoon, Iain D. C. Fraser, Aleksandra Nita‐Lazar   +5 more
wiley   +1 more source

Quantitative Host Cell Protein Analysis of Antibody-Based Protein Therapeutics Using the Orbitrap Astral Mass Spectrometer. [PDF]

J Am Soc Mass Spectrom
Smith J, Richardson A, Beaumal C, Ainciburu M, Carillo S, Pashkova A, Arrey TN, Damoc NE, Clarke C, Bones J.   +9 more
europepmc   +1 more source

Proteomic Profiling of Primary Hippocampal Neurons Reveals Noncanonical GFAP Expression and Metabolic Adaptations in Glia‐Free Culture

PROTEOMICS, EarlyView.
ABSTRACT Despite their widespread use as a research model, a comprehensive, quantitative proteomic profile of the cultured hippocampal neurons has remained unexplored. Here, we provide the first global proteomic characterization of primary murine hippocampal neurons cultured for 14 days under near‐physiological glucose conditions (2.5 mM).
Dominika Drulis‐Fajdasz, Kinga Gostomska‐Pampuch, Natalia Pudełko‐Malik, Mariusz Fleszar, Agnieszka Gizak, Jacek R. Wiśniewski, Dariusz Rakus   +6 more
wiley   +1 more source

Rapid bacteriophage quantification with a particle size analyzer combined with polarization intensity differential scattering (PIDS) detector. [PDF]

PLoS One
Carroll-Portillo A, Braun CA, Martinez E, Lin HC.   +3 more
europepmc   +1 more source

Enabling Variant Proteogenomic Assay Development Through a Peptide Target Selection Pipeline and Web Application

PROTEOMICS, EarlyView.
ABSTRACT The quantification of key protein variants can guide precision oncology to enable better identification of driver mutations. Bottom‐up assays infer parent protein levels through the quantification of surrogate peptides. Assay methods designed for absolute quantification of protein variants, such as multiple reaction monitoring mass ...
Constantinos Blidjios, Pallab Bhowmick, Vincent R. Richard, Yassene Mohammed, Christoph H. Borchers   +4 more
wiley   +1 more source

<i>In situ</i> generation of dendritic cell vaccines in 3D printing scaffolds for cancer post-surgical therapy. [PDF]

Natl Sci Rev
Chen L, Xu Y, Hu X, Pan Y, She P, Chen X, Peng Q, Li Q, Rao L.   +8 more
europepmc   +1 more source