Results 171 to 180 of about 327,904 (307)

Transcriptional Profiling of Growth Hormone-Secreting Pituitary Adenoma Stem-Like Cells: Unveiling the Significant Role of CXCR4 in Tumorigenesis and Clinical Applications. [PDF]

MedComm (2020)
Yuan L, Yang H, Li B, Sui H, Li P, Wang X, Li J, Jia G, Zhu Z, Li D, Jia W, Kang P.   +11 more
europepmc   +1 more source

Majorbio Cloud 2026 Update: An End‐to‐End Solution for Proteomics Research

iMetaMed, EarlyView.
The recent upgrade of Majorbio Cloud facilitates a more streamlined and accurate research process, aiding researchers across the various proteomics subfields. Furthermore, it propels the advancement of multi‐layered, multi‐omics scientific investigations centered around proteins.
Caiping Shi, Chang Han, Jichen Han, Bing Yang, Yachen Dong, Jianhua Zhao, Binxu Liu, Rundong Fang, Wenyao Fu, Jiawen Ma, Meng Luo, Lixing Feng, Yitong Feng, Huimin Cui, Mengxi Li, Huasheng Huang, Xianglin Zhang, Kegang Yu   +17 more
wiley   +1 more source

Selective loss of primary cilia and neurotrophic signaling in G51D α-synuclein mice highlights a common pathway to Parkinson's disease. [PDF]

Proc Natl Acad Sci U S A
Lin YE, Jaimon E, Kim Y, Loftman A, Vijayakumaran A, Belfort BDW, Chiang CY, Arenkiel BR, Zoghbi HY, Pfeffer SR.   +9 more
europepmc   +1 more source

Peptide selection for targeted protein quantitation

Targeted proteomics methods in their different flavors rely on the use of a few peptides as proxies for protein quantitation, which need to be specified either prior to or after data acquisition.
Sabidó Aguadé, Eduard, 1981-, Chiva, Cristina   +1 more
core  

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Editorial: Advances in plant proteomics

Frontiers in Plant Science, 2022
Joshua L. Heazlewood, Ian S. Wallace, Shou-Ling Xu   +2 more
doaj   +1 more source

On-Column Preparation of High-Performance Affinity Chromatography Columns. [PDF]

Anal Chem
Gilar M, Muriithi B, Sarisozen YT, Wuthrich P, Donegan M, Wyndham KD.   +5 more
europepmc   +1 more source

Metabolic feature profiling and metabolic vulnerability in acute lymphoblastic leukemia

Interdisciplinary Medicine, EarlyView.
For the first time, our study develops a novel metabolic classification and subtyping program, metabolic reprogramming‐based classifier for acute lymphoblastic leukemia, using internal PDT‐ALL‐2016 and external cohorts, which dissects metabolic profiling, clinical outcome, and therapeutic vulnerability for precision metabolic intervention in ALL ...
Xiaojie Liang, Zihong Cai, Bingqing Tang, Zicong Huang, Baiwei Luo, Bingyu Lin, Yunong Yang, Zhihao Jin, Xiaoqing Li, Xiuli Xu, Yeling Deng, Chaoran Lin, Liang Wang, Hongsheng Zhou   +13 more
wiley   +1 more source

Overcoming Electrochemiluminescence Immunoassay (ECLIA) Limitations: Conformation-Independent Quantitation of a Therapeutic Antibody by LC-MS/MS. [PDF]

Anal Chem
Gaither C, Popp R, Maheshwari P, Lemus M, Laurin J, Filion M, Borchers CH.   +6 more
europepmc   +1 more source

GSK3β drives early diabetic tubulopathy via TFEB‐mediated mitochondrial dysfunction

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction, including mitochondrial biogenesis, mitophagy, dynamics and oxidative stress, occurs in the early stages of diabetic tubulopathy, which precede proteinuria and renal histological changes. GSK3β is a potential novel biomarker for the prediction of diabetic tubulopathy.
Lan Yao, Xianhui Liang, Bingyu Li, Bohan Chen, Xiaoyang Wang, Mei Hong, Qi Feng, Yingjin Qiao, Zhangsuo Liu, Kai Wang, Pei Wang   +10 more
wiley   +1 more source