Results 171 to 180 of about 498,441 (308)

Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends

Clinical Pharmacology &Therapeutics, EarlyView.
Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer, Ellen Cannady, Filip Cuyckens, Ulrike Glaenzel, Camille Granvil, Felix Huth, Alexander D. James, Wenying Li, Céline Veau, Graeme Young, Qin Yue, Gregory S. Walker, Upendra A. Argikar, Jonathan N. Bauman, Cathy Cantalloube, Yu‐Luan Chen, Ping Kang, Patricia Moliner, Mette L. Pedersen, Isabel Piel, Simone Schadt, Hanno Schieferstein, Julia Suchomel, Shuai Wang, S. Cyrus Khojasteh   +24 more
wiley   +1 more source

Superior transplant recipient outcome prediction and pathology assessment using rapid deep learning applied to procurement kidney biopsies. [PDF]

Sci Rep
Gaut JP, Marsh JN, Chen L, Zhang F, Yu X, Wilson P, Liu TC, Swamidass SJ.   +7 more
europepmc   +1 more source

Beyond PBMCs: Polymer‐Based Cell Mimics for Robust TBNK Immunophenotyping Assay Validation

Cytometry Part A, EarlyView.
ABSTRACT Flow cytometry‐based TBNK immunophenotyping is widely used to assess immune status in research, clinical diagnostics, and cell therapy development. Biological control materials such as PBMCs often serve as physiologically relevant controls, but suffer from considerable variability due to donor differences, limited stability, and fluctuations ...
Swetha Pratyusha Gunturu, Subhanip Biswas, Armando Martinez, Brian Kerfs, Kanwal Palla, Louisa D'Lima   +5 more
wiley   +1 more source

Rapid bacteriophage quantification with a particle size analyzer combined with polarization intensity differential scattering (PIDS) detector. [PDF]

PLoS One
Carroll-Portillo A, Braun CA, Martinez E, Lin HC.   +3 more
europepmc   +1 more source

Technical performance of a novel, fully automated electrochemiluminescence immunoassay for the quantitation of β-amyloid (1–42) in human cerebrospinal fluid [PDF]

, 2016
et al,, Gibson, David, Ostlund, Richard E, Jr.   +2 more
core   +2 more sources

In Vivo and In Vitro Evaluation of PTeCA (1H‐Pyrrole‐2,3,4,5‐Tetracarboxylic Acid) in Hair Matrix as a Marker for Oxidative Cosmetic Treatment

Drug Testing and Analysis, EarlyView.
A total of 3378 self‐reported treated and untreated hair samples were analyzed for PTCA and PTeCA by LC‐MS/MS. Moreover, their in vitro formation was assessed in 225 untreated hair by different cosmetic treatments with and without oxidative agents. Data suggest that PTeCA could be a reliable marker for oxidative cosmetic treatments in hair.
Sara Casati, Alessandro Ravelli, Roberta F. Bergamaschi, Agata Magliocco, Sofia Vanerio, Gabriella Roda, Paola Rota, Marica Orioli, Alessio Battistini   +8 more
wiley   +1 more source

Editorial: Advances in plant proteomics

Frontiers in Plant Science, 2022
Joshua L. Heazlewood, Ian S. Wallace, Shou-Ling Xu   +2 more
doaj   +1 more source

<i>In situ</i> generation of dendritic cell vaccines in 3D printing scaffolds for cancer post-surgical therapy. [PDF]

Natl Sci Rev
Chen L, Xu Y, Hu X, Pan Y, She P, Chen X, Peng Q, Li Q, Rao L.   +8 more
europepmc   +1 more source

Quantitative Proteomics [PDF]

Analytical Chemistry, 2013
John R, Yates, Michael P, Washburn
openaire   +2 more sources

Recreational Drug Use at a Music Festival: A Dual Approach Using Hair Biomarkers Analysis and Participant Self‐Reported Drug Use

Drug Testing and Analysis, EarlyView.
Combined self‐report and hair analysis in festival attendees (n = 249) revealed substantial discrepancies in drug use reporting, particularly for stimulants and dissociatives. This integrated approach enhances detection of poly‐drug use and provides a more reliable basis for monitoring and harm‐reduction strategies.
A. Y. Simão, T. Rosado, M. Barroso, M. Andraus, E. Gallardo   +4 more
wiley   +1 more source