Results 21 to 30 of about 264,803 (265)

Evaluation of ViroCyt® Virus Counter for Rapid Filovirus Quantitation

Viruses, 2015
Development and evaluation of medical countermeasures for diagnostics, vaccines, and therapeutics requires production of standardized, reproducible, and well characterized virus preparations. For filoviruses this includes plaque assay for quantitation of
Cynthia A. Rossi, Brian J. Kearney, Scott P. Olschner, Priscilla L. Williams, Camenzind G. Robinson, Megan L. Heinrich, Ashley M. Zovanyi, Michael F. Ingram, David A. Norwood, Randal J. Schoepp   +9 more
doaj   +3 more sources

Insights into the Mechanism of Separation of Bisphosphonates by Zwitterionic Hydrophilic Interaction Liquid Chromatography: Application to the Quantitation of Risedronate in Pharmaceuticals

Separations, 2019
Bisphosphonates are used to treat various skeletal disorders, as they modulate bone metabolism by inhibition of the osteoclast-mediated bone resorption.
Irene Panderi, Eugenia Taxiarchi, Constantinos Pistos, Eleni Kalogria, Ariadni Vonaparti   +4 more
doaj   +1 more source

MODERN STEREOLOGICAL EVALUATION IN THE AGING HUMAN SUBSTANTIA NIGRA

Image Analysis and Stereology, 2011
Quantitative estimation of neuronal numbers in the human substantia nigra (SN) can be achieved by a conventional single section (SS) count or by the more modern stereological disector (DS) count.
Shuang Y Ma, Frank M Longo, Matias Röyttä, Yrjö Collan   +3 more
doaj   +1 more source

Anthocyanin Characterization, Total Phenolic Quantification and Antioxidant Features of Some Chilean Edible Berry Extracts

Molecules, 2014
The anthocyanin composition and HPLC fingerprints of six small berries endemic of the VIII region of Chile were investigated using high resolution mass analysis for the first time (HR-ToF-ESI-MS).
Anghel Brito, Carlos Areche, Beatriz Sepúlveda, Edward J. Kennelly, Mario J. Simirgiotis   +4 more
doaj   +1 more source

Pharmacokinetics and metabolism of ketoconazole after single ocular instillation in Sprague-Dawley rats

ADMET and DMPK
Background and purpose: Ketoconazole is limited to its conditioned oral use due to hepatic toxicity. Its ocular eye drop administration may be an option for mycotic keratitis treatment.
Jiang Pu, Jingsong He, Ru Xue, Ruiqi Gao, Yaoming Yu, Wanyong Feng   +5 more
doaj   +1 more source

Qualitative and Quantitative Analysis Method of Recombinant Collagen in Complex Matrix Based on HPLC-MS/MS

Separations
The purpose of this study is to achieve the quantitative detection of recombinant type III collagen (rh-COL-III) in dressings with complex matrix. First of all, the marker peptide (GEAGIPGVPGAK) of rhCOL-III was identified with HPLC-MS/MS.
Jianping Gao, Liping Jia, Zhenhu Guo, Liming Xu, Daidi Fan, Guifeng Zhang   +5 more
doaj   +1 more source

Quantitative Determination of Four Potential Genotoxic Impurities in the Active Pharmaceutical Ingredients in TSD-1 Using UPLC-MS/MS

Molecules, 2022
A novel method of ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) was developed for the identification and quantification of four potential genotoxic impurities (PGIs) in the active pharmaceutical ingredients of TSD-1, a ...
Taiyu Wang, Hailong Yang, Jie Yang, Ningjie Guo, Guodong Wu, Xueyu Xu, Ming An   +6 more
doaj   +1 more source

Improved intact peptide and protein quantitation by LC‐MS: Battling the deleterious effects of analyte adsorption

Analytical Science Advances, 2021
Peptide and protein quantitation by liquid chromatography‐mass spectrometry relies on the assumption of linear signal response with concentration. At low concentrations, analyte adsorption to pipette tips, sample vials and equipment can have significant ...
EmmaRae L. Murphy, Andrew P. Joy, Rodney J. Ouellette, David A. Barnett   +3 more
doaj   +1 more source

Standardization of SARS-CoV-2 Cycle Threshold Values: Multisite Investigation Evaluating Viral Quantitation across Multiple Commercial COVID-19 Detection Platforms

Microbiology Spectrum, 2023
The demand for testing during the coronavirus disease 2019 (COVID-19) pandemic has resulted in the production of several different commercial platforms and laboratory-developed assays for the detection of severe acute respiratory syndrome coronavirus 2 ...
Kenneth Gavina, Lauren C. Franco, Christopher M. Robinson, Weston Hymas, Guang-Sheng Lei, Will Sinclair, Tara Hall, John Carlquist, John-Paul Lavik, Christopher L. Emery, Phillip R. Heaton, David Hillyard, Bert K. Lopransi, Ryan F. Relich   +13 more
doaj   +1 more source

Harmonized procedures lead to comparable quantification of total oxylipins across laboratories

Journal of Lipid Research, 2020
Oxylipins are potent lipid mediators involved in a variety of physiological processes. Their profiling has the potential to provide a wealth of information regarding human health and disease and is a promising technology for translation into clinical ...
Malwina Mainka, Céline Dalle, Mélanie Pétéra, Jessica Dalloux-Chioccioli, Nadja Kampschulte, Annika I. Ostermann, Michael Rothe, Justine Bertrand-Michel, John W. Newman, Cécile Gladine, Nils Helge Schebb   +10 more
doaj   +1 more source