Results 31 to 40 of about 264,803 (265)

Phytochemical profiling of the stem bark of Betula utilis from different geographical regions of India using UHPLC‐ESI‐MS/MS

open access: yesAnalytical Science Advances, 2021
A simple, rapid, sensitive, and reliable ultra‐high‐performance liquid chromatography‐hybrid linear ion trap triple quadrupole mass spectrometry method was developed and validated for simultaneous determination of 10 bioactive compounds in stem bark of ...
Tripti Mishra   +7 more
doaj   +1 more source

Rapid measurement of serum caffeine concentrations in acuteclinical settings

open access: yesToxicology Communications, 2021
The number of acute caffeine poisoning cases have increased in Japan. We can use serum caffeine concentrations to evaluate the severity of caffeine poisoning and determine whether or not we should perform hemodialysis. In this study, we sought to develop
Tomoki Hanazawa   +3 more
doaj   +1 more source

Gas-liquid chromatographic analysis of free long-chain aldehydes

open access: yesJournal of Lipid Research, 1969
Quantitative results are reported for gas-liquid chromatography of mixtures of free tetra-, hexa-, and octadecanals and cis-9-octadecenal on polar and nonpolar liquid phases.
Randall Wood, R.D. Harlow
doaj   +1 more source

Hist-Immune signature: a prognostic factor in colorectal cancer using immunohistochemical slide image analysis

open access: yesOncoImmunology, 2020
Computerized image analysis for whole-slide images has been shown to improve efficiency, accuracy, and consistency in histopathology evaluations. We aimed to assess whether immunohistochemistry (IHC) image quantitative features can reflect the immune ...
Ke Zhao   +10 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Analysis of Pesticide Residues on Fruit Using Swab Spray Ionization Mass Spectrometry

open access: yesMolecules, 2023
The vast quantity and high variety of pesticides globally used in agriculture entails considerable risks for the environment and requires ensuring the safety of food products.
Thomas Michael Muggli, Stefan Schürch
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Fluocell for Ratiometric and High-Throughput Live-Cell Image Visualization and Quantitation

open access: yesFrontiers in Physics, 2019
Spatiotemporal regulation of molecular activities dictates cellular function and fate. Investigation of dynamic molecular activities in live cells often requires the visualization and quantitation of fluorescent ratio image sequences with subcellular ...
Qin Qin   +8 more
doaj   +1 more source

Quantitative Capillary Electrophoresis for Analysis of Extracellular Vesicles (EVqCE)

open access: yesSeparations, 2021
Extracellular Vesicles (EVs) gained significant interest within the last decade as a new source of biomarkers for the early detection of diseases and a promising tool for therapeutic applications.
Yuchu Dou   +4 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

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