Results 31 to 40 of about 498,441 (308)

MODERN STEREOLOGICAL EVALUATION IN THE AGING HUMAN SUBSTANTIA NIGRA

open access: yesImage Analysis and Stereology, 2011
Quantitative estimation of neuronal numbers in the human substantia nigra (SN) can be achieved by a conventional single section (SS) count or by the more modern stereological disector (DS) count.
Shuang Y Ma   +3 more
doaj   +1 more source

Validated UPLC-MS/MS methods to quantitate free and conjugated Alternaria toxins in commercially available tomato products and fruit and vegetable juices in Belgium [PDF]

open access: yes, 2016
Ultraperformance liquid chromatography tandem mass spectrometry and Quick, Easy, Cheap, Effective, Rugged, and Safe based analytical methodologies to quantitate both free (alternariol (1), alternariol monomethyl ether (2), tenuazonic acid (3), tentoxin ...
Asam, Stefan   +10 more
core   +3 more sources

Quantitative testing [PDF]

open access: yesProceedings of the 8th ACM international conference on Embedded software, 2008
We investigate the problem of specification based testing with dense sets of inputs and outputs, in particular with imprecision as they might occur due to errors in measurements, numerical instability or noisy channels. Using quantitative transition systems to describe implementations and specifications, we introduce implementation relations that ...
Bohnenkamp, H.C.   +1 more
openaire   +2 more sources

Therapeutic Drug Monitoring and Methods of Quantitation for Carbamazepine [PDF]

open access: yes, 2017
Carbamazepine is an early anticonvulsant still used today in the treatment of several forms of epilepsy. An active metabolite in the human body contributes to its pharmacological effect.
Ana Vlasceanu   +7 more
core   +4 more sources

Anthocyanin Characterization, Total Phenolic Quantification and Antioxidant Features of Some Chilean Edible Berry Extracts

open access: yesMolecules, 2014
The anthocyanin composition and HPLC fingerprints of six small berries endemic of the VIII region of Chile were investigated using high resolution mass analysis for the first time (HR-ToF-ESI-MS).
Anghel Brito   +4 more
doaj   +1 more source

A quantitative assay to monitor HSV-1 ICP0 ubiquitin ligase activity in vitro [PDF]

open access: yes, 2015
The ubiquitin–proteasome system is an essential cellular process that plays a fundamental role in the regulation of protein stability. This pathway is tightly controlled by a sequential cascade of enzymatic steps that culminates in the formation of a ...
Boutell, Chris, Davido, David J.
core   +2 more sources

Pharmacokinetics and metabolism of ketoconazole after single ocular instillation in Sprague-Dawley rats

open access: yesADMET and DMPK
Background and purpose: Ketoconazole is limited to its conditioned oral use due to hepatic toxicity. Its ocular eye drop administration may be an option for mycotic keratitis treatment.
Jiang Pu   +5 more
doaj   +1 more source

Qualitative and Quantitative Analysis Method of Recombinant Collagen in Complex Matrix Based on HPLC-MS/MS

open access: yesSeparations
The purpose of this study is to achieve the quantitative detection of recombinant type III collagen (rh-COL-III) in dressings with complex matrix. First of all, the marker peptide (GEAGIPGVPGAK) of rhCOL-III was identified with HPLC-MS/MS.
Jianping Gao   +5 more
doaj   +1 more source

Quantitative Determination of Four Potential Genotoxic Impurities in the Active Pharmaceutical Ingredients in TSD-1 Using UPLC-MS/MS

open access: yesMolecules, 2022
A novel method of ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) was developed for the identification and quantification of four potential genotoxic impurities (PGIs) in the active pharmaceutical ingredients of TSD-1, a ...
Taiyu Wang   +6 more
doaj   +1 more source

Highly efficient optogenetic cell ablation in C. elegans using membrane-targeted miniSOG. [PDF]

open access: yes, 2016
The genetically encoded photosensitizer miniSOG (mini Singlet Oxygen Generator) can be used to kill cells in C. elegans. miniSOG generates the reactive oxygen species (ROS) singlet oxygen after illumination with blue light.
Chisholm, Andrew D, Xu, Suhong
core   +1 more source

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