Results 41 to 50 of about 498,441 (308)

Improved intact peptide and protein quantitation by LC‐MS: Battling the deleterious effects of analyte adsorption

open access: yesAnalytical Science Advances, 2021
Peptide and protein quantitation by liquid chromatography‐mass spectrometry relies on the assumption of linear signal response with concentration. At low concentrations, analyte adsorption to pipette tips, sample vials and equipment can have significant ...
EmmaRae L. Murphy   +3 more
doaj   +1 more source

Standardization of SARS-CoV-2 Cycle Threshold Values: Multisite Investigation Evaluating Viral Quantitation across Multiple Commercial COVID-19 Detection Platforms

open access: yesMicrobiology Spectrum, 2023
The demand for testing during the coronavirus disease 2019 (COVID-19) pandemic has resulted in the production of several different commercial platforms and laboratory-developed assays for the detection of severe acute respiratory syndrome coronavirus 2 ...
Kenneth Gavina   +13 more
doaj   +1 more source

Site-specific identification and quantitation of endogenous SUMO modifications under native conditions. [PDF]

open access: yes, 2017
Small ubiquitin-like modifier (SUMO) modification regulates numerous cellular processes. Unlike ubiquitin, detection of endogenous SUMOylated proteins is limited by the lack of naturally occurring protease sites in the C-terminal tail of SUMO proteins ...
Ahmad, Alla S   +8 more
core   +2 more sources

Harmonized procedures lead to comparable quantification of total oxylipins across laboratories

open access: yesJournal of Lipid Research, 2020
Oxylipins are potent lipid mediators involved in a variety of physiological processes. Their profiling has the potential to provide a wealth of information regarding human health and disease and is a promising technology for translation into clinical ...
Malwina Mainka   +10 more
doaj   +1 more source

Phytochemical profiling of the stem bark of Betula utilis from different geographical regions of India using UHPLC‐ESI‐MS/MS

open access: yesAnalytical Science Advances, 2021
A simple, rapid, sensitive, and reliable ultra‐high‐performance liquid chromatography‐hybrid linear ion trap triple quadrupole mass spectrometry method was developed and validated for simultaneous determination of 10 bioactive compounds in stem bark of ...
Tripti Mishra   +7 more
doaj   +1 more source

Rapid measurement of serum caffeine concentrations in acuteclinical settings

open access: yesToxicology Communications, 2021
The number of acute caffeine poisoning cases have increased in Japan. We can use serum caffeine concentrations to evaluate the severity of caffeine poisoning and determine whether or not we should perform hemodialysis. In this study, we sought to develop
Tomoki Hanazawa   +3 more
doaj   +1 more source

Ametryn removal by Metarhizium brunneum: Biodegradation pathway proposal and metabolic background revealed [PDF]

open access: yes, 2018
Ametryn is a representative of a class of s-triazine herbicides absorbed by plant roots and leaves and characterized as a photosynthesis inhibitor. It is still in use in some countries in the farming of pineapples, soybean, corn, cotton, sugar cane or ...
Abigail   +48 more
core   +1 more source

Detection of equine atypical myopathy-associated hypoglycin A in plant material: Optimisation and validation of a novel LC-MS based method without derivatisation [PDF]

open access: yes, 2018
Hypoglycin A (HGA) toxicity, following ingestion of material from certain plants, is linked to an acquired multiple acyl-CoA dehydrogenase deficiency known as atypical myopathy, a commonly fatal form of equine rhabdomyolysis seen worldwide.
González-Medina, S   +3 more
core   +2 more sources

Gas-liquid chromatographic analysis of free long-chain aldehydes

open access: yesJournal of Lipid Research, 1969
Quantitative results are reported for gas-liquid chromatography of mixtures of free tetra-, hexa-, and octadecanals and cis-9-octadecenal on polar and nonpolar liquid phases.
Randall Wood, R.D. Harlow
doaj   +1 more source

Hist-Immune signature: a prognostic factor in colorectal cancer using immunohistochemical slide image analysis

open access: yesOncoImmunology, 2020
Computerized image analysis for whole-slide images has been shown to improve efficiency, accuracy, and consistency in histopathology evaluations. We aimed to assess whether immunohistochemistry (IHC) image quantitative features can reflect the immune ...
Ke Zhao   +10 more
doaj   +1 more source

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