Results 61 to 70 of about 327,904 (307)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Analysis and Discrimination of Canadian Honey Using Quantitative NMR and Multivariate Statistical Methods

Molecules, 2023
To address the growing concern of honey adulteration in Canada and globally, a quantitative NMR method was developed to analyze 424 honey samples collected across Canada as part of two surveys in 2018 and 2019 led by the Canadian Food Inspection Agency ...
Ian W. Burton, Mohsen Kompany-Zareh, Sophie Haverstock, Jonathan Haché, Camilo F. Martinez-Farina, Peter D. Wentzell, Fabrice Berrué   +6 more
doaj   +1 more source

ZIKV RNA detection and quantitation.

, 2016
ZIKV RNA detection and quantitation.
Stephanie O. D. da Cruz (3163749), Alexandra L. Gerber (123121), Luana Damasceno (3163767), Alexandre A. C. dos Santos (3163743), Iasmim S. de Mello (3163776), Ricardo Lourenço-de-Oliveira (257382), Lidiane S. R. Menezes (3163755), Ana Tereza R. Vasconcelos (123140), Marcia G. de Castro (3163773), Patrícia Brasil (411818), Luiz G. P. de Almeida (3163761), Kely A. B. da Silva (3163770), Nathália D. Furtado (3163752), Elaine E. de Moura (3163758), Noemia S. Lima (3163746), Ieda P. Ribeiro (3163764), Myrna C. Bonaldo (102764)   +16 more
core   +1 more source

Multifunctional Neutrophil Nanovesicles Induce Remodeling of Tumor Immune Microenvironment and Synergistic Multimodal Tumor Therapy

Advanced Functional Materials, EarlyView.
Schematic illustration of the engineered RN@FDT for multimodal tumor therapy. a) Fabrication of FD&DOX/TFA‐loaded RGD‐NNV (RN@FDT) and the light‐triggered disassemble of RN@FDT. b) After internalized by tumor cells, RN@FDT are disintegrated under NIR‐II laser irradiation to boost PTT and induce cell apoptosis.
Jiahui Zhang, Cheng Ji, Xin‐Jian Fang, Yu Qian, Jiayuan Shi, Wenhui Liu, Baiyuan Fan, Yuan Zhong, Jiayi Wang, Dan Yu, Maoye Wang, Min Fu, Xiaoxin Zhang, Runbi Ji, Hélder A. Santos, Hongbo Zhang, Xu Zhang   +16 more
wiley   +1 more source

Development of an immunoblot assay with infrared fluorescence to quantify paraoxonase 1 in serum and plasma

Journal of Lipid Research, 2008
Paraoxonase 1 (PON1) requires calcium for activity and is inactivated in the presence of EDTA. Because of this, studies to date have used serum or heparinized plasma for both activity and mass assays of PON1.
Philip W. Connelly, Graham F. Maguire, Clive M. Picardo, John F. Teiber, Dragomir Draganov   +4 more
doaj   +1 more source

Instrumentation for Routine Analysis of Acrylamide in French Fries: Assessing Limitations for Adoption

Foods, 2021
The purpose of this experimental review was to detect acrylamide in French fries using methods most adaptable to the food process industry for quality control assessment of products. French fries were prepared at different cook times using the same fryer
Mark M. Skinner, Jared T. Seale, Maranda S. Cantrell, Joseph M. Collins, Matthew W. Turner, Owen M. McDougal   +5 more
doaj   +1 more source

ATP‐Mediated Bidirectional Communication Between Natural and Artificial Cells for Controlled Bioreactions

Advanced Functional Materials, EarlyView.
Establishment of bidirectional communication behavior between natural and artificial cells. The first type of communication from natural dendritic cells to artificial polymeric cells was achieved via ATP release after cell lysis. The released ATP was taken up via gated UV‐controlled permeability increase of the polymeric membrane for performing ...
Ilona Kalte, Tsvetomir Ivanov, Leonhard Seufert, Shoupeng Cao, Lucas Caire da Silva, Volker Mailänder, Katharina Landfester   +6 more
wiley   +1 more source

AI‐Powered Framework for Evaluating Drug Efficacy for Three‐Dimensional In Vitro Cancer Models in Robot‐Assisted Production

Advanced Robotics Research, EarlyView.
An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy, Jesus Nieves, Lukas Königer, Matthias Peindl, Fabio Erhard, Marc Möllmann, Anke Klingner, Markus Münig, Bibin Babu, Thomas Schwarz, Marco Metzger, Gudrun Dandekar, Maximiliane Wußmann, Jan Hansmann   +13 more
wiley   +1 more source

Quantitative profiling of endocannabinoids and related N-acylethanolamines in human CSF using nano LC-MS/MS

Journal of Lipid Research, 2017
Endocannabinoids, a class of lipid messengers, have emerged as crucial regulators of synaptic communication in the CNS. Dysregulation of these compounds has been implicated in many brain disorders.
Vasudev Kantae, Shinji Ogino, Marek Noga, Amy C. Harms, Robin M. van Dongen, Gerrit L.J. Onderwater, Arn M.J.M. van den Maagdenberg, Gisela M. Terwindt, Mario van der Stelt, Michel D. Ferrari, Thomas Hankemeier   +10 more
doaj   +1 more source

Separating chiral isomers of amphetamine and methamphetamine using chemical derivatization and differential mobility spectrometry

Analytical Science Advances, 2020
The separation and analysis of chiral compounds, especially enantiomers, presents a great challenge to modern analytical chemistry, particularly to mass spectrometry (MS).
J. Larry Campbell, Amol Kafle, Zack Bowman, J. C. Yves Le Blanc, Chang Liu, W. Scott Hopkins   +5 more
doaj   +1 more source