Results 41 to 50 of about 383,746 (345)

Hist-Immune signature: a prognostic factor in colorectal cancer using immunohistochemical slide image analysis

open access: yesOncoImmunology, 2020
Computerized image analysis for whole-slide images has been shown to improve efficiency, accuracy, and consistency in histopathology evaluations. We aimed to assess whether immunohistochemistry (IHC) image quantitative features can reflect the immune ...
Ke Zhao   +10 more
doaj   +1 more source

Quantitation of the cellular content of saliva and buccal swab samples

open access: yesScientific Reports, 2018
Buccal swabs and saliva are the two most common oral sampling methods used for medical research. Often, these samples are used interchangeably, despite previous evidence that both contain buccal cells and blood leukocytes in different proportions.
C. Theda   +5 more
semanticscholar   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Analysis of Pesticide Residues on Fruit Using Swab Spray Ionization Mass Spectrometry

open access: yesMolecules, 2023
The vast quantity and high variety of pesticides globally used in agriculture entails considerable risks for the environment and requires ensuring the safety of food products.
Thomas Michael Muggli, Stefan Schürch
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Fluocell for Ratiometric and High-Throughput Live-Cell Image Visualization and Quantitation

open access: yesFrontiers in Physics, 2019
Spatiotemporal regulation of molecular activities dictates cellular function and fate. Investigation of dynamic molecular activities in live cells often requires the visualization and quantitation of fluorescent ratio image sequences with subcellular ...
Qin Qin   +8 more
doaj   +1 more source

Quantitative Capillary Electrophoresis for Analysis of Extracellular Vesicles (EVqCE)

open access: yesSeparations, 2021
Extracellular Vesicles (EVs) gained significant interest within the last decade as a new source of biomarkers for the early detection of diseases and a promising tool for therapeutic applications.
Yuchu Dou   +4 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

UTE MRI technical developments and applications in osteoporosis: a review

open access: yesFrontiers in Endocrinology
Osteoporosis (OP) is a metabolic bone disease that affects more than 10 million people in the USA and leads to over two million fractures every year. The disease results in serious long-term disability and death in a large number of patients.
Soo Hyun Shin   +14 more
doaj   +1 more source

Hybrid Imaging for Patient-Specific Dosimetry in Radionuclide Therapy

open access: yesDiagnostics, 2015
Radionuclide therapy aims to treat malignant diseases by systemic administration of radiopharmaceuticals, often using carrier molecules such as peptides and antibodies.
Michael Ljungberg   +1 more
doaj   +1 more source

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