Results 151 to 160 of about 4,302,850 (309)

Rate of double reduction and genetic variability in yield, quality, and senescence related traits in tetraploid potato (Solanum tuberosum L.)

Frontiers in Plant Science
The amount of genetic variability is the foundation for genetic change in any plant breeding program, and the amount of double reduction can influence genetic gain and the amount of future genetic diversity in polyploid species.
Muhammad Farhan Yousaf, Muhammad Farhan Yousaf, Vipin Tomar, Hélène Romé, Merethe Bagge, Mathias Timmermann, Thinh Tuan Chu, Just Jensen   +7 more
doaj   +1 more source

A comparative analysis of agronomic water-use efficiency and its proxy measures as derived from key morpho-physiological and supportive quantitative genetics attributes of perennial ryegrass under imposed drought. [PDF]

Plant Environ Interact, 2023
Weerarathne LVY, Jahufer Z, Schäufele R, Lopez I, Matthew C.   +4 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Conceptualizing the evolutionary quantitative genetics of phenological life-history events: Breeding time as a plastic threshold trait. [PDF]

Evol Lett, 2022
Reid JM, Acker P.
europepmc   +1 more source

Grapevine pangenome facilitates trait genetics and genomic breeding

Nature Genetics
Grapevine breeding is hindered by a limited understanding of the genetic basis of complex agronomic traits. This study constructs a graph-based pangenome reference (Grapepan v.1.0) from 18 newly generated phased telomere-to-telomere assemblies and 11 ...
Zhongjie Liu, Nan Wang, Ying Su, Qiming Long, Yanling Peng, Lingfei Shangguan, Fan Zhang, Shuo Cao, Xu Wang, Mengqing Ge, Hui Xue, Zhiyao Ma, Wenwen Liu, Xiaodong Xu, Chaochao Li, Xuejing Cao, Bilal Ahmad, Xiangnian Su, Yuting Liu, Guizhou Huang, Mengrui Du, Zhenya Liu, Yu Gan, Lei Sun, Xiucai Fan, Chuan Zhang, H. Zhong, X. Leng, Yanhua Ren, Tianyu Dong, Dan Pei, Xinyu Wu, Zhongxin Jin, Yiwen Wang, Chonghuai Liu, Jinfeng Chen, Brandon S. Gaut, Sanwen Huang, Jinggui Fang, Hua Xiao, Yongfeng Zhou   +40 more
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Quantitative Genetics [PDF]

Evolution, 1999
Trudy F. C. Mackay, Michael Lynch, Bruce Walsh   +2 more
openaire   +2 more sources

Restoring fertility in yeast hybrids: Breeding and quantitative genetics of beneficial traits. [PDF]

Proc Natl Acad Sci U S A, 2021
Naseeb S, Visinoni F, Hu Y, Hinks Roberts AJ, Maslowska A, Walsh T, Smart KA, Louis EJ, Delneri D.   +8 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Quantitative Genetics of Smoltification Status at the Time of Seawater Transfer in Atlantic Salmon (Salmo Salar). [PDF]

Front Genet, 2021
Khaw HL, Gjerde B, Boison SA, Hjelle E, Difford GF.   +4 more
europepmc   +1 more source