Results 81 to 90 of about 4,302,850 (309)

Allelic heterogeneity and trade-off shape natural variation for response to soil micronutrient [PDF]

, 2012
Peer reviewedPublisher ...
Andreatta, Matthew, Loudet, Olivier, Poormohammad Kiani, Seifollah, Robert, Thierry, Salt, David E, Simon, Matthieu, Trontin, Charlotte   +6 more
core   +6 more sources

Genome-wide identification and expression analysis of the SET domain-containing gene family in potato (Solanum tuberosum L.)

BMC Genomics
Genes containing the SET domain can catalyse histone lysine methylation, which in turn has the potential to cause changes to chromatin structure and regulation of the transcription of genes involved in diverse physiological and developmental processes ...
Vithusan Suppiyar, Venkata Suresh Bonthala, Asis Shrestha, Stephanie Krey, Benjamin Stich   +4 more
doaj   +1 more source

Statistical model and testing designs to increase response to selection with constrained inbreeding in genomic breeding programs for pigs affected by social genetic effects

Genetics Selection Evolution, 2021
Background Social genetic effects (SGE) are the effects of the genotype of one animal on the phenotypes of other animals within a social group. Because SGE contribute to variation in economically important traits for pigs, the inclusion of SGE in ...
Thinh Tuan Chu, Mark Henryon, Just Jensen, Birgitte Ask, Ole Fredslund Christensen   +4 more
doaj   +1 more source

Functional genomics bridges the gap between quantitative genetics and molecular biology

Genome Research, 2015
Deep characterization of molecular function of genetic variants in the human genome is becoming increasingly important for understanding genetic associations to disease and for learning to read the regulatory code of the genome.
T. Lappalainen
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Evolutionary-thinking in agricultural weed management [PDF]

, 2009
Agricultural weeds evolve in response to crop cultivation. Nevertheless, the central importance of evolutionary ecology for understanding weed invasion, persistence and management in agroecosystems is not widely acknowledged.
Ainsworth, Ainsworth, Andersson, Arntz, Ashley, Baker, Baker, Ball, Barberi, Barrett, Barrett, Barrett, Barton, Beckie, Beckie, Booth, Buhler, Burnside, Busi, Carroll, Cavers, Chapman, Cleland, Clements, Clements, Cocker, Connell, Cousens, Cousens, Coustau, Dauer, Derksen, Diggle, Drake, Dunbabin, Elena, Ellstrand, Fabrice Roux, Fernandez-Quintanilla, Franks, Franks, Fried, Fuhrer, Genton, Ghersa, Gressel, Gressel, Grime, Hairston, Hald, Hamrick, Harper, Hawes, Heap, Heap, Hermisson, Holst, Ianetta, Jacquemin, Jander, Jordan, Jordan, Jordan, Kassen, Kirchner, Lande, Lande, Le Corre, Le Roux, Leiss, Lenormand, Martin Vila-Aiub, Maxwell, Mayr, McCloskey, Menchari, Menchari, Merilä, Michael, Morgan, Mortensen, Mortimer, Moss, Naylor, Neve, Neve, Neve, Neve, Neve, Novak, Oerke, Orr, Orr, Owen, Patterson, Paul Neve, Pedersen, Pimentel, Plowman, Powles, Powles, Powles, Preston, Ray, Reboud, Reboud, Reboud, Reed, Roux, Roux, Roux, Roux, Roux, Ruegg, Ryan, Sahli, Salzmann, Sherry, Smith, Sultan, Swanton, Tabashnik, Tardif, Thompson, Van Acker, Van Valen, Vila-Aiub, Wang, Warwick, Warwick, Warwick, Warwick, Warwick, Weaver, Weiner, Weinig, Westra, Wijngaarden, Wilczek, Willi, Ziska   +140 more
core   +2 more sources

Accurate recombination estimation from pooled genotyping and sequencing: a case study on barley

BMC Genomics, 2022
Sexual reproduction involves meiotic recombination and the creation of crossing over between homologous chromosomes, which leads to new allele combinations. We present a new approach that uses the allele frequency differences and the physical distance of
Michael Schneider, Federico Casale, Benjamin Stich   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Impact of kinship matrices on genetic gain and inbreeding with optimum contribution selection in a genomic dairy cattle breeding program

Genetics Selection Evolution, 2023
Background Genomic selection has increased genetic gain in dairy cattle, but in some cases it has resulted in higher inbreeding rates. Therefore, there is need for research on efficient management of inbreeding in genomically-selected dairy cattle ...
Egill Gautason, Goutam Sahana, Bernt Guldbrandtsen, Peer Berg   +3 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source