Results 71 to 80 of about 6,396,260 (376)

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha   +6 more
wiley   +1 more source

The Dynamic Window Approach as a Tool to Improve Performance of Nonparametric Self-Starting Control Charts

open access: yesMathematics
The change-point model is an established methodology for the construction of self-starting control charts. Change-point charts are often nonparametric in order to be independent from any specific assumptions about the process distribution.
Claudio Giovanni Borroni   +2 more
doaj   +1 more source

Quantitative regularity for parabolic De Giorgi classes [PDF]

open access: yesarXiv, 2019
We deal with the De Giorgi H{\"o}lder regularity theory for parabolic equations with rough coefficients and parabolic De Giorgi classes which extend the notion of solution. We give a quantitative proof of the interior H{\"o}lder regularity estimate for both using De Giorgi method.
arxiv  

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Borges Dilemma, Fundamental Laws, and Systems Biology [PDF]

open access: yesarXiv, 2007
I reason here that the known folk law in biology that there is no general law in biology because of exceptions is false. The (quantitative) systems biology offers the potential to solve the Borges Dilemma, by transcending it. There have already a plenty of indications on this trend.
arxiv  

A researcher's dilemma- philosphical and methodological pluralism [PDF]

open access: yes, 2004
In many research textbooks the distinction between qualitative and quantitative research is inadvertently linked with philosophical perspectives. This in essence creates a mutually exclusive relationship between method and philosophy.
Knox, KT
core  

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Factors Influencing User Perception and Adoption of E-Government Services

open access: yesAdministrative Sciences
The objective of this study is to investigate and determine factors influencing user perception and acceptance of electronic government services in the context of technological advancements.
Galina Ilieva   +7 more
doaj   +1 more source

Joinpoint regression analysis with time-on-study as time-scale. Application to three Italian population-based cohort studies

open access: yesEpidemiology, Biostatistics and Public Health, 2017
Background: Joinpoint regression analysis is usually applied to study varying trends over time in order to identify the time point(s) in which the trend significantly changes.
Eleonora Pagan   +6 more
doaj   +1 more source

Methods for prioritization: Toward quantitative approach to prioritize zoonoses in South East Asia [PDF]

open access: yes, 2011
Resources for research, surveillance, control and others public health activities are limited and it is difficult to compare the importance of diseases, which vary in terms of occurrence, impacts, etc. So, in this context of scarce resources and multiple
Bordier, Marion   +3 more
core  

Home - About - Disclaimer - Privacy