Results 41 to 50 of about 1,079,378 (256)

Diversité des méthodes utilisées par les laboratoires français pour la surveillance des infections à cytomégalovirus humain [PDF]

, 2012
Monitoring cytomegalovirus circulating viral load is an important parameter of the follow-up in immunocompromised patients. It can be measured either by DNAemia or by pp65 antigenemia.
A. Slim, B. Boyer, Groupe Contrôle de qualité national cytomégalovirus, L. Mhiri, M. Goudard, M. Leruez-Ville, M.C. Mazeron, S. Alain   +7 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Serum CCAT2 as a biomarker for adjuvant diagnosis and prognostic prediction of cervical cancer

Journal of Ovarian Research, 2022
Growing evidence indicates that lncRNA colon cancer-associated transcript 2 (CCAT2) is associated with cancers. However, the clinical value of CCAT2 in cervical cancer (CC) remains unclear.
Xiaoli Cao, Juan Yao, Meiqun Jia, Xianjuan Shen, Jinye Zhang, Shaoqing Ju   +5 more
doaj   +1 more source

Quantitative detection of soybean in meat products by a TaqMan real-time PCR assay [PDF]

, 2014
In the present work, we propose a normalised real-time quantitative PCR assay to determine the addition of soybean to meat products. The method proved to be a powerful tool for the quantification of soybean protein (dry basis) in the range of 0.01% to 6%,
Amaral, Joana S., Mafra, I., Oliveira, Beatriz, Soares, Sónia   +3 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Simultaneous Quantitative Detection of Relevant Biomarkers in Breast Cancer by Quantitative Real-Time PCR

The International Journal of Biological Markers, 2006
The assessment of ERα, PgR and HER2 status is routinely performed today to determine the endocrine responsiveness of breast cancer samples. Such determination is usually accomplished by means of immunohistochemistry and in case of HER2 amplification by ...
M. Labuhn, V. Vuaroqueaux, F. Fina, A. Schaller, I. Nanni-Metellus, W. Küng, S. Eppenberger-Castori, P.M. Martin, U. Eppenberger   +8 more
doaj   +1 more source

Quantitative Determination of Lentiviral Vector Particle Numbers by Real-Time PCR

BioTechniques, 2001
Here, we describe a quantitative, DNAbased, real-time PCR approach to determine the number of lentivirus particles that are present in vector preparations.
M. Scherr, K. Battmer, U. Blömer, A. Ganser, M. Grez   +4 more
doaj   +1 more source

Involvement of Fenton chemistry in rice straw degradation by the lignocellulolytic bacterium Pantoea ananatis Sd-1 [PDF]

, 2016
Additional file 7: Table S2.
Bin Liu, Chunyi Tong, Jiangshan Ma, Jiarui Zeng, Keke Zhang, Mei Huang, Qian Liu, Stanton B. Hector, Ting Xu, Xuanming Liu, Yan Gao, Ying Liu, Yonghua Zhu   +12 more
core   +6 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Identification and validation of stable reference genes for quantitative real time PCR in different minipig tissues at developmental stages

BMC Genomics, 2022
Background Quantitative real time PCR (qPCR) is a powerful tool to evaluate mRNA expression level. However, reliable qPCR results require normalization with validated reference gene(s).
Jeongah Song, Jeonghee Cho, Jeongsik Park, Jeong Ho Hwang   +3 more
doaj   +1 more source