Background Phosphorus is an essential nutrient in all living organisms and, currently, it is the focus of much attention due to its global scarcity, the environmental impact of phosphorus from excreta, and its low digestibility due to its storage in the ...
Valentin Haas +5 more
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Explaining the heritability of an ecologically significant trait in terms of individual quantitative trait loci [PDF]
Most natural populations display substantial genetic variation in behaviour, morphology, physiology, life history and the susceptibility to disease. A major challenge is to determine the contributions of individual loci to variation in complex traits.
Alison G, Scoville +3 more
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Understanding Disease Susceptibility through Population Genomics [PDF]
Genetic epidemiology studies have established that the natural variation of gene expression profiles is heritable and has genetic bases. A number of proximal and remote DNA variations, known as expression quantitative trait loci (eQTLs), that are ...
Seonggyun Han, Junnam Lee, Sangsoo Kim
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Heritability of quantitative autism spectrum traits in adults: A
AbstractAutism spectrum disorder (ASD) comprises a multi‐dimensional set of quantitative behavioral traits expressed along a continuum in autistic and neurotypical individuals. ASD diagnosis—a dichotomous trait—is known to be highly heritable and has been used as the phenotype for most ASD genetic studies.
Sara C. Taylor +18 more
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Developmental and genetic effects on behavioral and life‐history traits in a field cricket
A fundamental goal of evolutionary ecology is to identify the sources underlying trait variation on which selection can act. Phenotypic variation will be determined by both genetic and environmental factors, and adaptive phenotypic plasticity is expected
Tina W. Wey +2 more
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An Effective Method to Identify Heritable Components from Multivariate Phenotypes.
Multivariate phenotypes may be characterized collectively by a variety of low level traits, such as in the diagnosis of a disease that relies on multiple disease indicators. Such multivariate phenotypes are often used in genetic association studies.
Jiangwen Sun, Henry R Kranzler, Jinbo Bi
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To individualise breast cancer (BC) prevention, markers to follow a person’s changing environment and health extending beyond static genetic risk scores are required.
Chiara Herzog +10 more
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Biased estimators of quantitative trait locus heritability and location in interval mapping [PDF]
In many empirical studies, it has been observed that genome scans yield biased estimates of heritability, as well as genetic effects. It is widely accepted that quantitative trait locus (QTL) mapping is a model selection procedure, and that the overestimation of genetic effects is the result of using the same data for model selection as estimation of ...
M, Bogdan, R W, Doerge
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Regional Heritability Mapping of Quantitative Trait Loci Controlling Traits Related to Growth and Productivity in Popcorn (Zea mays L.) [PDF]
The method of regional heritability mapping (RHM) has become an important tool in the identification of quantitative trait loci (QTLs) controlling traits of interest in plants. Here, RHM was first applied in a breeding population of popcorn, to identify the QTLs and candidate genes involved in grain yield, plant height, kernel popping expansion, and ...
Gabrielle Sousa Mafra +16 more
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A major QTL controls susceptibility to spinal curvature in the
Background Understanding the genetic basis of heritable spinal curvature would benefit medicine and aquaculture. Heritable spinal curvature among otherwise healthy children (i.e.
Dreyer Christine +6 more
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