Results 31 to 40 of about 21,627 (244)

Gene expression genetics of the striatum of Diversity Outbred mice

Scientific Data, 2023
Brain transcriptional variation is a heritable trait that mediates complex behaviors, including addiction. Expression quantitative trait locus (eQTL) mapping reveals genomic regions harboring genetic variants that influence transcript abundance.
Vivek M. Philip, Hao He, Michael C. Saul, Price E. Dickson, Jason A. Bubier, Elissa J. Chesler   +5 more
doaj   +1 more source

Identification of Quantitative Trait Loci Determining Vegetative Growth Traits in Coffea canephor

Coffee and Cocoa Research Journal, 2011
Recently the use of molecular markers has been successfully applied for some crops. For coffee, new opportunities have been opened since Nestlé R&D Centre in collaboration with ICCRI completed the first genetic map of Coffea canephora.
Priyono Priyono, Ucu Sumirat, Crouzillat Crouzillat   +2 more
doaj   +1 more source

Quantitative genetic analysis deciphers the impact of cis and trans regulation on cell-to-cell variability in protein expression levels.

PLoS Genetics, 2020
Identifying the factors that shape protein expression variability in complex multi-cellular organisms has primarily focused on promoter architecture and regulation of single-cell expression in cis.
Michael D Morgan, Etienne Patin, Bernd Jagla, Milena Hasan, Lluís Quintana-Murci, John C Marioni   +5 more
doaj   +1 more source

Genetic analysis of genome-scale recombination rate evolution in house mice. [PDF]

PLoS Genetics, 2011
The rate of meiotic recombination varies markedly between species and among individuals. Classical genetic experiments demonstrated a heritable component to population variation in recombination rate, and specific sequence variants that contribute to ...
Beth L Dumont, Bret A Payseur
doaj   +1 more source

Quantitative trait locus mapping and analysis of heritable variation in affiliative social behavior and co‐occurring traits [PDF]

Genes, Brain and Behavior, 2017
Humans exhibit broad heterogeneity in affiliative social behavior. Twin and family studies show that individual differences in core dimensions of social behavior are heritable, yet there are knowledge gaps in understanding the underlying genetic and neurobiological mechanisms.
Knoll, A. T., Jiang, K., Levitt, P.
openaire   +2 more sources

A stable and major QTL region on chromosome 2 conditions pod shape in cultivated peanut (Arachis hyopgaea L.)

Journal of Integrative Agriculture, 2023
Peanut pod shape is a heritable trait which affects the market acceptance of in-shell peanut products. In order to determine the genetic control of pod shape, six component traits of pod shape (pod length, pod width, pod length/width ratio, pod roundness,
Sheng-zhong ZHANG, Xiao-hui HU, Fei-fei WANG, Ye CHU, Wei-qiang YANG, Sheng XU, Song WANG, Lan-rong WU, Hao-liang YU, Hua-rong MIAO, Chun FU, Jing CHEN   +11 more
doaj   +1 more source

Expression Quantitative Trait Loci in Equine Skeletal Muscle Reveals Heritable Variation in Metabolism and the Training Responsive Transcriptome

Frontiers in Genetics, 2019
While over ten thousand genetic loci have been associated with phenotypic traits and inherited diseases in genome-wide association studies, in most cases only a relatively small proportion of the trait heritability is explained and biological mechanisms ...
Gabriella Farries, Kenneth Bryan, Charlotte L. McGivney, Paul A. McGettigan, Katie F. Gough, John A. Browne, David E. MacHugh, David E. MacHugh, Lisa Michelle Katz, Emmeline W. Hill, Emmeline W. Hill   +10 more
doaj   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Disease resistance in Atlantic salmon (Salmo salar): coinfection of the intracellular bacterial pathogen Piscirickettsia salmonis and the sea louse Caligus rogercresseyi. [PDF]

PLoS ONE, 2014
BACKGROUND: Naturally occurring coinfections of pathogens have been reported in salmonids, but their consequences on disease resistance are unclear. We hypothesized that 1) coinfection of Caligus rogercresseyi reduces the resistance of Atlantic salmon to
Jean Paul Lhorente, José A Gallardo, Beatriz Villanueva, María J Carabaño, Roberto Neira   +4 more
doaj   +1 more source

Impulsivity is a heritable trait in rodents and associated with a novel quantitative trait locus on chromosome 1 [PDF]

Scientific Reports, 2020
AbstractImpulsivity describes the tendency to act prematurely without appropriate foresight and is symptomatic of a number of neuropsychiatric disorders. Although a number of genes for impulsivity have been identified, no study to date has carried out an unbiased, genome-wide approach to identify genetic markers associated with impulsivity in ...
Jupp, Bianca, Pitzoi, Silvia, Petretto, Enrico, Mar, Adam C, Oliver, Yolanda Pena, Jordan, Emily R, Taylor, Stephanie, Atanur, Santosh S, Srivastava, Prashant K, Saar, Kathrin, Hubner, Norbert, Sommer, Wolfgang H, Staehlin, Oliver, Spanagel, Rainer, Robinson, Emma S, Schumann, Gunter, Moreno, Margarita, Everitt, Barry J, Robbins, Trevor W, Aitman, Timothy J, Dalley, Jeffrey W   +20 more
openaire   +7 more sources