Metabolomics of Eryngium heterophyllum by UHPLC-QToF-MS and In Silico Insights Into Potential Metabolic Syndrome Targets. [PDF]
Chem BiodiversEryngium heterophyllum has 85 metabolites according to nontargeted UHPLC‐QTOF‐MS profiling, with flavonoids and phenylpropionic acids emerging as significantly related bioactive families. In silico compound–disease–target networks connect 31 metabolites to inflammation, diabetes, obesity, and cardiovascular disease associated with metabolic syndrome ...
Gutiérrez-Rodelo C +5 more
europepmc +2 more sources
Comparative Evaluation of the Cytotoxic Effect of Dysphania ambrosioides Extracts Against Human Breast and Cervical Cancer Cells. [PDF]
Chem BiodiversThis study evaluates the geographic influence on the chemical and biological profiles of Dysphania ambrosioides collected from Brazilian and Colombian sources. Following extraction, metabolic fingerprinting via HPLC‐MS reveals distinct phytochemical variations between the geographical origins.
Abadia ACM +6 more
europepmc +2 more sources
Extraction and Isolation of Bioactive Compounds From Malpighia glabra L. Leaves: In Vivo Investigation of the Leaf Extract Against Oxidative Stress and Inflammation Triggered by γ-Radiation. [PDF]
Chem BiodiversMalpighia glabra L. leaves extract, enriched with flavonoids and β‐isoarborinol, exhibits antioxidant and anti‐inflammatory activities that moderate γ‐radiation‐induced systemic and tissue harm. The extract preserves intestinal, hepatic, renal, splenic, and systemic integrity by reducing oxidative stress and inflammation, supporting its potential as a ...
Fekry AM +4 more
europepmc +2 more sources
Antidiabetic Effect of <i>Phanera strychnifolia</i> (Craib) K. W. Jiang, S. R. Gu, & T. Y. Tu Extracts in Streptozotocin-Induced Diabetic Rats by Upregulating Insulin Secretion and Glucose Transporter 2 and 4 Protein Expression. [PDF]
Scientifica (Cairo)Diabetes mellitus, a condition characterized by hyperglycemia, poses significant global health concern. Despite the availability of several antidiabetic drugs, the search for new therapeutic agents with fewer side effects and better efficacy continues. Phanera strychnifolia (Craib) K. W. Jiang, S. R. Gu, & T. Y. Tu, a medicinal plant traditionally used
Lao-On K +5 more
europepmc +2 more sources
Fitoquímica e quimiossistemática de Euxylophora paraensis (Rutaceae)
Química Nova, 2012 Phytochemical studies of the leaves and stem have led to the identification of the known coumarins isooxypeucedanin, oxypeucedanin hydrate, xanthotoxin, isopimpinellin, 8-methoxymarmesin and marmesin, flavonoids quercetin-3-O-α-L-rhamnopyranoside ...
Marsele Machado Isidoro +5 more
doaj +1 more source
Molecules, 2022 Despite the rapid advances in drug R&D, there is still a huge need for antibacterial medications, specifically for the methicillin-resistant Staphylococcus aureus (MRSA).
Xiying Wu +8 more
doaj +1 more source
PHYTOCHEMICAL AND BIOLOGICAL INVESTIGATION OF KOELREUTERIA ELEGANS (SEEM.) LEAVES [PDF]
Al-Azhar Journal of Pharmaceutical Sciences, 2022 A new galloylquinic acid butyl ester; 1, 3, 4, 5-tetra-O-galloylquinic acid butyl ester(1) and other ten known phenolic compounds : 1,3,4,5-tetra-O-galloylquinic acid (2) , methyl gallate (3), gallic acid (4) , 3"-galloyl quercetrin (5), isorhamnetin-3 ...
Dina El Naggar
doaj +1 more source
Anti-Babesial Compounds from Mill
Natural Product Communications, 2007 Bioassay-guided investigation of extracts of the flowers of Rosa damascena Mill. led to the isolation of four anti-babesial compounds, 3,4-dihydroxy benzoic acid ( 1 ), gallic acid ( 2 ), 2-phenylethyl 6- O -galloyl-β-D-glucopyranoside ( 3 ), and ...
Ahmed Elkhateeb +5 more
doaj +1 more source
Anti-HIV-1 integrase and anti-allergic activities of Bauhinia strychnifolia [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2013 A stem ethanol extract of Bauhinia strychnifolia and its compounds were investigated for their anti-HIV-1 integrase (IN) and anti-allergic activities.
Kingkan Bunluepuech +3 more
doaj
Two New Acylated Flavonol Glycosides from the Seeds of Lepidium sativum
Molecules, 2014 Two new acylated flavonol glycosides named kaempferol-3-O-(2-O-sinapoyl)-β-D-galactopyranosyl-(1→2)-β-D-glucopyranoside-7-O-α-L-rhamnopyranoside (1) and quercetin-3-O-(6-O-benzoyl)-β-D-glucopyranosyl-(1→3)-β-D-galactopyranoside-7-O-α-L-rhamnopyranoside ...
Qing-Lu Fan +4 more
doaj +1 more source