Results 101 to 110 of about 18,476 (212)

NAD(P)H:quinone oxidoreductase 1 inducer activity of some novel anilinoquinazoline derivatives [PDF]

, 2016
The Kelch-like ECH-associated protein 1 (Keap1)/nuclear factor erythroid 2-related factor 2 (Nrf2)/antioxidant response elements pathway enables cells to survive oxidative stress conditions through regulating the expression of cytoprotective enzymes such
Alsaid, Mansour S, Arafa, Reem K, Dinkova-Kostova, Albena T, Elghazawy, Nehal H, Ghorab, Mostafa M, Higgins, Maureen, Shahat, Abdelaaty A   +6 more
core   +3 more sources

Quinazoline Derivatives as Green Corrosion Inhibitors for Carbon Steel in Hydrochloric Acid Solutions

International Journal of Electrochemical Science, 2013
The inhibiting effect of some quinazoline derivatives on the corrosion of carbon steel in 2 M HCl was studied by weight loss, potentiodynamic polarization, electrochemical impedance spectroscopy (EIS), scanning electron microscopy (SEM) and energy ...
A.S. Fouda, A.M. El-desoky, Hala M. Hassan   +2 more
doaj   +1 more source

Combined 3D-QSAR modeling and molecular docking study on multi-acting quinazoline derivatives as HER2 kinase inhibitors [PDF]

, 2013
A series of new quinazoline derivatives has been recently reported as potent multi-acting histone deacetylase (HDAC), epidermal growth factor receptor (EGFR), and human epidermal growth factor receptor 2 (HER2) inhibitors.
Fathi, Fardin, Hakhamaneshi, Mohammad Saeed, Jamalan, Mostafa, Mirzaie, Sako, Monajjemi, Majid   +4 more
core  

QUINAZOLINES. PART I.

, 1937
QUINAZOLINES. PART I.
openaire   +1 more source

Amino-quinazolines [PDF]

Nature, 1945
A. KILLEN MACBETH, HAROLD J. RODDA
openaire   +1 more source

Discovery of A Novel Series of Quinazoline–Thiazole Hybrids as Potential Antiproliferative and Anti-Angiogenic Agents

Biomolecules
Considering the pivotal role of angiogenesis in solid tumor progression, we developed a novel series of quinazoline–thiazole hybrids (SA01–SA07) as antiproliferative and anti-angiogenic agents.
Alexandru Șandor, Ionel Fizeșan, Ioana Ionuț, Gabriel Marc, Cristina Moldovan, Ilioara Oniga, Adrian Pîrnău, Laurian Vlase, Andreea-Elena Petru, Ioana Macasoi, Ovidiu Oniga   +10 more
doaj   +1 more source

Efficient solid-phase synthesis of 1,2,3-benzotriazin-4-ones with SynPhaseTM Lanterns

Journal of the Brazilian Chemical Society, 2003
We have developed a solid-phase synthesis of 1,2,3-benzotriazin-4-ones through cyclization of 2-aminobenzamides via diazotization. The development of an efficient synthesis is important from the viewpoint of drug discovery, considering the various ...
Makino Shingo, Nakanishi Eiji, Tsuji Takashi   +2 more
doaj  

Exploring Quinazoline as a Scaffold for Developing Novel Therapeutics in Alzheimer’s Disease

Molecules
Quinazoline, a privileged scaffold in medicinal chemistry, offers promising potential in the synthesis of anti-Alzheimer’s disease (AD) drugs. This heterocyclic compound, characterized by its fused benzene and pyrimidine rings, enables the design of ...
Qais Abualassal, Zead Abudayeh, Ala’ Sirhan, Abdulrahman Mkia   +3 more
doaj   +1 more source

The crystal and molecular structure of 1,3-diazanaphthalene [PDF]

, 1976
Huiszoon, C.
core   +4 more sources

Comparative Analysis of Molecular Docking Programs GOLD, Glide, and MOE on Quinazoline Derivatives as Antiproliferative Agents: Implications for EGFR-Targeted Therapies

Al-Mustansiriyah Journal of Pharmaceutical Sciences
Background: To aid in the identification of drug candidates and the prediction of protein-ligand interactions, molecular docking predicts how ligands interact with receptors, aiding drug discovery.
Ali Hussein Sabr, Monther Faisal Mahdi, Talal Aburjai   +2 more
doaj   +1 more source