Results 91 to 100 of about 24,939 (257)

Dynamic Kinetic Resolution of Hetero biaryl Ketones by Zinc- Catalyzed Asymmetr ic Hydrosil ylation [PDF]

, 2019
Adiastereo- and highly enantioselective dynamic kinetic resolution (DKR) of configurationally labile hetero- biaryl ketones is described. The DKR proceeds by zinc- catalyze dhydrosilylation of the carbonyl group ,thus leading to ...
Carmona, José A., Fernández Fernández, Rosario Fátima, Hornillos, Valentín, Iglesias Sigüenza, Francisco Javier, Lassaletta, José M., López Serrano, Joaquín, Ros Lao, Abel   +6 more
core   +1 more source

Sunflower-Assisted Bio-Derived ZnO-NPs as an Efficient Nanocatalyst for the Synthesis of Novel Quinazolines with Highly Antioxidant Activities [PDF]

, 2022
S. Suma Mahesh, Boya Palajonnala Narasaiah, B. Himabindu, G. Balaji, Jangampalli Adi Pradeepkiran, Harihara Padhy   +5 more
openalex   +1 more source

Novel Quinazoline Derivatives as Highly Effective A2A Adenosine Receptor Antagonists

Molecules
The adenosine A2A receptor (A2AR) has been identified as a therapeutic target for treating neurodegenerative diseases and cancer. In recent years, we have highlighted the 2-aminoquinazoline heterocycle as an promising scaffold for designing new A2AR ...
Amélie Laversin, Robin Dufossez, Raphaël Bolteau, Romain Duroux, Séverine Ravez, Sergio Hernandez-Tapia, Martin Fossart, Mathilde Coevoet, Maxime Liberelle, Saïd Yous, Nicolas Lebègue, Patricia Melnyk   +11 more
doaj   +1 more source

Synthesis and anticancer activities of diquinazoline diselenides compounds [PDF]

, 2016
A series of novel diquinazoline diselenide compounds was designed and synthesized with substituted 4-chloroquinazoline and sodium diselenide. Their structures were confirmed by IR, 1H NMR, 13C NMR, and elemental analyses.The antitumor activity of the new
Cao, Kun, Huang, YinJiu, Ji, ChunNuan, Liu, Gang, Liu, XiGuang, Sun, Lin, Xu, ShengGuang   +6 more
core  

Analgetic Activity of a Quinazoline

Experimental Biology and Medicine, 1967
SummaryFour test systems were used to demonstrate the analgetic activity of Su-13026, a quinazoline compound, in mice, rats and rabbits. Signs of central nervous system stimulation were noted. Respiration was not depressed in any of the species studied. Nalorphine did not antagonize, nor did amphetamine potentiate, the activity of this compound in mice.
H I, Chernov, H M, Blatter, P S, Bernard, D E, Wilson, A J, Plummer   +4 more
openaire   +2 more sources

Quinazolines. Part IV.

, 1936
Quinazolines. Part IV.
SANT SINGH BEDI, KARTAR SINGH NARANG
openaire   +1 more source

Quinazoline compounds for antitumor treatment

Experimental Oncology, 2023
Summary. Quinazolines are among the most useful heterocyclic compounds due to their diverse chemical reactivity and a wide range of biological activity. Despite a large number of publications devoted to quinazolines and their derivatives, information is presented predominantly regarding the features of the synthesis of these compounds and their ...
openaire   +2 more sources

Synthesis, Modelling, and Anticonvulsant Studies of New Quinazolines Showing Three Highly Active Compounds with Low Toxicity and High Affinity to the GABA-A Receptor

Molecules, 2017
Some novel fluorinated quinazolines (5a–j) were designed and synthesized to be evaluated for their anticonvulsant activity and their neurotoxicity. Structures of all newly synthesized compounds were confirmed by their infrared (IR), mass spectrometry (MS)
Mohamed F. Zayed, Saleh K. Ihmaid, Hany E. A. Ahmed, Khaled El-Adl, Ahmed M. Asiri, Abdelsattar M. Omar   +5 more
doaj   +1 more source

Coupling of alpha(1)-Adrenoceptors to ERK1/2 in the Human Prostate [PDF]

, 2011
Introduction: alpha(1)-Adrenoceptors are considered critical for the regulation of prostatic smooth muscle tone. However, previous studies suggested further alpha(1)-adrenoceptor functions besides contraction.
Anglin IE, Boris Schlenker, Chang L, Chon JK, Christ GJ, Christian G. Stief, Christian Gratzke, Erdogru T, Frank Strittmatter, Glassman DT, Golomb E, Johanna Göttinger, Kanagawa K, Karl-Erik Andersson, Kyprianou N, Kyprianou N, Kyprianou N, Lucia MS, Luthin GR, Marinese D, Maroni PD, Martin Hennenberg, McCubrey JA, McVary KT, Michel MC, Oliver Reich, Petter Hedlund, Ricarda M. Bauer, Roehrborn CG, Roehrborn CG, Royuela M, Royuela M, Schilit S, Schwinn DA, Shimada K, Srinivasan D, Turkeri LN, Xiao L, Zhang H, Zhang Z   +39 more
core   +1 more source

Structure Activity Relationship and Molecular Docking of Some Quinazolines Bearing Sulfamerazine Moiety as New 3CLpro, cPLA2, sPLA2 Inhibitors [PDF]

, 2023
Mohammed A. Hussein, Rita M. Borik, Mohamed S. Nafie, Heba M. Abo‐Salem, Sylvia A. Boshra, Zahraa N. Mohamed   +5 more
openalex   +1 more source