Results 81 to 90 of about 24,939 (257)

Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides

open access: yesMolecules, 2002
The reaction of N-(2-cyanophenyl)benzimidoyl chloride with reagents containing a thioamide moiety, i.e. thioacetamide, benzylthiourea, symmetrical dialkyl- and diarylthioureas gave different cyclic products: 3,1-benzothiazine, 1,3,5-benzotriazocine and ...
Pavel Pazdera, Walid M. Fathalla
doaj   +1 more source

Carbon-13 n.m.r. investigation on the nitrogen methylation of the mono- and diazanaphthalenes [PDF]

open access: yes, 1977
The 13C n.m.r. spectra of the N-methylated mono- and diazanaphthalenes have been recorded and analysed. It has been shown that N-methylation as well as N-protonation in cinnoline occur predominantly at the -nitrogen atom.
Ham, Dirk M.W. van den   +2 more
core   +2 more sources

Microwave‐Assisted Organic Syntheses in Deep Eutectic Solvents: A Win‐Win Association for Sustainable Chemistry

open access: yesChemistryOpen, Volume 15, Issue 4, April 2026.
In organic synthesis, deep eutectic solvents (DES) have demonstrated their ability to be used as reaction media for the development of reactions in line with green chemistry principles. This review presents an overview of microwave‐assisted organic synthesis in DES, highlighting the diversity of uses for these solvents, their role in mechanisms, the ...
Pierre‐Olivier Delaye   +2 more
wiley   +1 more source

NAD(P)H:Quinone oxidoreductase 1 inducer activity of novel 4-aminoquinazoline derivatives [PDF]

open access: yes, 2016
Fourteen novel 4-aminoquinazoline derivatives 2-15 were designed and synthesized. The structure of the newly synthesized compounds was established on the basis of elemental analyses, IR, (1)H-NMR, (13)C-NMR, and mass spectral data.
Abdelaaty A. Shahat   +11 more
core   +2 more sources

A Convenient One‐Pot CuI‐Catalyzed Procedure for the Synthesis of S‐(N‐Heteroaryl) Thiocarboxylates From N‐Heteroaryl Bromides and Thiobenzoic Acid

open access: yesChemistryOpen, Volume 15, Issue 4, April 2026.
A one‐pot two‐step CuI‐catalyzed procedure for the synthesis of S‐(N‐heteroaryl) thiocarboxylates from N‐heteroaryl bromides and thiobenzoic acid was developed, which is highlighted by shorter reaction time, a smaller amount of iodide source and scalability.
Jiamin Pan   +4 more
wiley   +1 more source

Regioselective Suzuki-Miyaura Reaction: Application to the Microwave-promoted Synthesis of 4,7-Diarylquinazolines

open access: yesMolecules, 2010
New diarylquinazolines displaying pharmaceutical potential were synthesized in high yields from 4,7-dichloro-2-(2-methylprop-1-enyl)-6-nitroquinazoline by using microwave-promoted regioselective Suzuki-Miyaura cross-coupling reactions.
Patrice Vanelle   +3 more
doaj   +1 more source

Polycyclic N-Hetero Compounds. XL. Reaction of Cyclic Ketones with Trisformylaminomethane [PDF]

open access: yes, 1991
Reactions of cyclic ketones such as α-tetralone, 1,3-cyclohexanedione, or naphthalenedione with formamide or trisformylaminomethane (TFAM) have shown to form polyclic fused pyrimidines by us.
Hirota, Kazuhiro   +3 more
core   +1 more source

Comprehensive Analysis of Structure Activity Relationships in Quinoxaline Derivatives Covering Antimicrobial Applications

open access: yesChemistrySelect, Volume 11, Issue 14, 13 April 2026.
ABSTRACT Antimicrobial resistance (AMR) has emerged as one of the most critical global health challenges, undermining the clinical efficacy of existing antibiotics and threatening modern therapeutic strategies. The ongoing misuse and overuse of antimicrobial agents have accelerated the evolution of resistant bacterial strains and parasites ...
Subham Kumar Vishwakarma   +2 more
wiley   +1 more source

AI‐Augmented Iterative Screening of Libraries Against RNA Targets (AISLAR) Boosts Discovery of SAR‐Tractable RNA Binders and Rational Analog Design

open access: yesSmall Science, Volume 6, Issue 4, April 2026.
AI‐augmented iterative screening of libraries against RNA targets (AISLAR) combines fluorescence resonance energy transfer screening, machine learning, and validation by dose response and isothermal titration calorimetry to discover RNA binders. Applied to p53 mRNA motifs, AISLAR identified chemotypes with tractable structure–activity relationships ...
Haruhiko Hattori   +6 more
wiley   +1 more source

Synthesis and antibacterial activity of 2-phenyl-5-aryl-4, 5, 6, 7, 8, 9-hexahydro-1,2.4-triazolo[1,5-A]quinazolines [PDF]

open access: yes, 2013
A method for the synthesis of 2-phenyl-5-aryl-4, 5, 6, 7, 8,9- hexahydrotriazolo[1,5-a] quinazolines was developed.3-Amino-5-phenyl-1,2,4-triazole formed Schiff’s bases with aromatic aldehydes which on treatment with cyclohexanonein the presence of ...
Ain Khan, Misbahul   +4 more
core  

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