Results 101 to 110 of about 13,731 (218)

Expedient Synthesis of 4-Aryl Quinazoline Analogues via Direct Nucleophilic Arylation of 2-Chloroquinazoline

, 2016
A practical approach was developed for the synthesis of 4-aryl quinazoline compounds via a one-pot nucleophilic arylation of 2-chloro-quinazoline with aryl lithiums generated in situ, followed by ring oxidation.
Yang Yang, Yang, Yang
core   +1 more source

Anti-cancer therapeutic potential of quinazoline based small molecules via global upregulation of miRNAs

, 2014
Three quinazoline based small molecules showed global upregulation of miRNA expression with a selective enrichment of tumor suppressor miRNAs. The target genes of the upregulated miRNAs were predicted to be enriched for apoptotic pathways.
Kumar Panja, Sumit, Maiti, Souvik, Bose, Debojit, Nahar, Smita, Saha, Satyen   +4 more
core   +1 more source

Efficient solid-phase synthesis of 1,2,3-benzotriazin-4-ones with SynPhaseTM Lanterns

Journal of the Brazilian Chemical Society, 2003
We have developed a solid-phase synthesis of 1,2,3-benzotriazin-4-ones through cyclization of 2-aminobenzamides via diazotization. The development of an efficient synthesis is important from the viewpoint of drug discovery, considering the various ...
Makino Shingo, Nakanishi Eiji, Tsuji Takashi   +2 more
doaj  

Synthesis of Pyrrolo[1,2-a]quinazoline Derivatives

Synthesis of pyrrolo[1,2-a]quinazoline ...
Zicāne, Daina, Tetere, Zenta, Rāviņa, Irisa, Rijkure, Inese   +3 more
core  

Discovery of new diaminoquinazolines against <i>Mycobacterium tuberculosis</i>: chemical synthesis and <i>in vitro</i> evaluation. [PDF]

RSC Adv
Kore M, Sundaramoorthy NS, Kidwai S, Singh R, Sundriyal S.   +4 more
europepmc   +1 more source

New quinazoline derivatives with anti-inflammatory activity and computationally predicted PDE7A binding: synthesis, molecular modeling, and <i>in silico</i> pharmacokinetic evaluation. [PDF]

Front Pharmacol
Alharbi M, Almagati AA, Gineinah MM, El-Malah AA, Hawsawi MB, Mantargi MJS, Aljahdali AS.   +6 more
europepmc   +1 more source

Synthesis and investigation of some quinazoline derivatives

, 2005
Bu çalışmada 2-Aminobenzil amin aldehidlerle karşılık gelen tetrahidrokinazolinleri 2 vermek üzere muamele edilmiştir. 2 Bileşiklerinin H2O2- tungstat beraberinde yükseltgenmesiyle karşılık gelen kinazolin-1 -oksitler 4 oluşur.
Çetin, Meliha
core  

Reprogramming RiPP scaffolds through skeletal editing unlocks chemical space. [PDF]

Chem Sci
Ogawa H, Yu L, Li S, Nagata Y, Chan TK, Matsuda Y, Liu J, Li YX, Nakamura H.   +8 more
europepmc   +1 more source

Prompt and Thermally Activated Delayed Fluorescence of Quinazoline‐Based Derivatives: a Joint Experimental and Theoretical Study

International audienceDuring the last decade, thermally activated delayed fluorescence has been the topic of intense research due to its great potential for highly efficient all organic light emitting devices.
Massue, Julien, Hodée, Maxime, Roisnel, Thierry, Fihey, Arnaud, Achelle, Sylvain, Nosova, Emiliya, Moshkina, Tatiana, Katan, Claudine   +7 more
core   +1 more source

Molecular docking, synthesis, and cytotoxic evaluation of novel quinazoline-quinazolinone hybrid compounds. [PDF]

Res Pharm Sci
Azarmi M, Rahimi S, Hormozi M, Rezaeinasab R.   +3 more
europepmc   +1 more source