Results 41 to 50 of about 18,476 (212)

Benzthiazoloneyl Quinazolines.

open access: yes, 1934
Benzthiazoloneyl Quinazolines.
PRAFULLA KUMAR BOSE, KUMUD BIHARI PATHAK
openaire   +1 more source

Photocatalytic Cross‐Coupling of Phenols and Heteroaryl Halides With Machine Learning‐Guided Reaction Prediction

open access: yesAngewandte Chemie International Edition, EarlyView.
Photocatalytic cross‐coupling: A redox‐neutral photochemical method enables direct C(sp2)─C(sp2) bond formation between phenols and heteroaryl halides using an organic dye and base. Complementary radical generation allows efficient cross‐coupling in up to 91% yield. Mechanistic studies, DFT, HTE, and machine learning rationalize and predict reactivity,
Matthew C. Carson   +4 more
wiley   +1 more source

Design, Synthesis and Anticancer Evaluation of Novel Quinazoline-Sulfonamide Hybrids

open access: yesMolecules, 2016
By combining the structural features of quinazoline and sulfonamides, novel hybrid compounds 2–21 were synthesized using a simple and convenient method.
Mostafa M. Ghorab   +4 more
doaj   +1 more source

Identification of Quinazolinone Analogs Targeting CDK5 Kinase Activity and Glioblastoma Cell Proliferation

open access: yesFrontiers in Chemistry, 2020
CDK5/p25 kinase plays a major role in neuronal functions, and is hyperactivated in several human cancers including glioblastoma and neurodegenerative pathologies such as Alzheimer's and Parkinson's.
Marion Peyressatre   +7 more
doaj   +1 more source

Medicinal Chemistry of Quinazolines as Analgesic and Anti-Inflammatory Agents

open access: yesChemEngineering, 2022
Quinazoline is an essential scaffold, known to be linked with various biological activities. Some of the prominent biological activities of this system are analgesic, anti-inflammatory, anti-hypertensive, anti-bacterial, anti-diabetic, anti-malarial ...
Mohamed F. Zayed
doaj   +1 more source

Synthesis, Characterization and Biological Activity Studies on 6-p-Dimethylaminophenyl-5,6-dihydrobenzoimidazo[1,2-c]quinazoline: Crystal Structure of the Title Compound and Comparative Study with Related Derivatives [PDF]

open access: yes, 2012
Reaction of o-aminophenylbenzimidazole with p-dimethylaminobenzaldehyde yielded 6-p-dimethylaminophenyl-5,6-dihydrobenzoimidazo[1,2-c]quinazoline, which was characterized by elemental analysis, IR, UV-Vis, H-1 NMR, C-13 NMR, mass spectral studies and X ...
Bhattacharjee, R.   +5 more
core   +1 more source

Synthetic Cathepsin B Sensitive Adjuvant‐Peptide Conjugates to Target Intracellular Toll‐Like Receptors 7 and 8

open access: yesChemistryEurope, EarlyView.
Cathepsin B‐sensitive peptide–adjuvant conjugates are designed, synthesized, and evaluated to deliver an antigenic peptid and an adjuvant targeting Toll‐like receptors 7 and 8 (TLR7/8) to antigen presenting cells. The adjuvant is released by cathepsin B resulting in antigen presentation and TLR mediated T cell activation.
Marjolein M. E. Isendoorn   +6 more
wiley   +1 more source

Microwave‐Assisted Organic Syntheses in Deep Eutectic Solvents: A Win‐Win Association for Sustainable Chemistry

open access: yesChemistryOpen, EarlyView.
In organic synthesis, deep eutectic solvents (DES) have demonstrated their ability to be used as reaction media for the development of reactions in line with green chemistry principles. This review presents an overview of microwave‐assisted organic synthesis in DES, highlighting the diversity of uses for these solvents, their role in mechanisms, the ...
Pierre‐Olivier Delaye   +2 more
wiley   +1 more source

Düşük Karbon Çeliğinin Asidik Ortamdaki Korozyonuna Karşı İnhibitör Özelliği Gösteren 4-Okso-Kinazolin Türevi Katyonik Yüzey Aktif Maddelerin Sentezi

open access: yesSakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2018
Birçok ülkede olduğu gibi bizimülkemizde de metal korozyonunu önlemeye yönelik kullanılan yöntemlerden biriuygun inhibitör kullanımıdır. Bu amaç doğrultusunda bu çalışmada,4-okso-kinazolin türevi olan uzun karbon zinciri içeren 3 adet katyonikpiridinyum ...
Serkan Öztürk
doaj   +1 more source

Signaling events involved in cytokine and chemokine production induced by secretory phospholipase A2 in human lung macrophages. [PDF]

open access: yes, 2006
7openopenGranata F; Frattini A; Loffredo S; Del Prete A; Sozzani S; Marone G; Triggiani M.Granata, F; Frattini, A; Loffredo, S; DEL PRETE, Annalisa; Sozzani, Silvano; Marone, G; Triggiani ...
DEL PRETE A   +6 more
core   +1 more source

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