Results 41 to 50 of about 18,476 (212)
Benzthiazoloneyl Quinazolines.
Benzthiazoloneyl Quinazolines.
PRAFULLA KUMAR BOSE, KUMUD BIHARI PATHAK
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Photocatalytic cross‐coupling: A redox‐neutral photochemical method enables direct C(sp2)─C(sp2) bond formation between phenols and heteroaryl halides using an organic dye and base. Complementary radical generation allows efficient cross‐coupling in up to 91% yield. Mechanistic studies, DFT, HTE, and machine learning rationalize and predict reactivity,
Matthew C. Carson +4 more
wiley +1 more source
Design, Synthesis and Anticancer Evaluation of Novel Quinazoline-Sulfonamide Hybrids
By combining the structural features of quinazoline and sulfonamides, novel hybrid compounds 2–21 were synthesized using a simple and convenient method.
Mostafa M. Ghorab +4 more
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CDK5/p25 kinase plays a major role in neuronal functions, and is hyperactivated in several human cancers including glioblastoma and neurodegenerative pathologies such as Alzheimer's and Parkinson's.
Marion Peyressatre +7 more
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Medicinal Chemistry of Quinazolines as Analgesic and Anti-Inflammatory Agents
Quinazoline is an essential scaffold, known to be linked with various biological activities. Some of the prominent biological activities of this system are analgesic, anti-inflammatory, anti-hypertensive, anti-bacterial, anti-diabetic, anti-malarial ...
Mohamed F. Zayed
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Synthesis, Characterization and Biological Activity Studies on 6-p-Dimethylaminophenyl-5,6-dihydrobenzoimidazo[1,2-c]quinazoline: Crystal Structure of the Title Compound and Comparative Study with Related Derivatives [PDF]
Reaction of o-aminophenylbenzimidazole with p-dimethylaminobenzaldehyde yielded 6-p-dimethylaminophenyl-5,6-dihydrobenzoimidazo[1,2-c]quinazoline, which was characterized by elemental analysis, IR, UV-Vis, H-1 NMR, C-13 NMR, mass spectral studies and X ...
Bhattacharjee, R. +5 more
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Cathepsin B‐sensitive peptide–adjuvant conjugates are designed, synthesized, and evaluated to deliver an antigenic peptid and an adjuvant targeting Toll‐like receptors 7 and 8 (TLR7/8) to antigen presenting cells. The adjuvant is released by cathepsin B resulting in antigen presentation and TLR mediated T cell activation.
Marjolein M. E. Isendoorn +6 more
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In organic synthesis, deep eutectic solvents (DES) have demonstrated their ability to be used as reaction media for the development of reactions in line with green chemistry principles. This review presents an overview of microwave‐assisted organic synthesis in DES, highlighting the diversity of uses for these solvents, their role in mechanisms, the ...
Pierre‐Olivier Delaye +2 more
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Birçok ülkede olduğu gibi bizimülkemizde de metal korozyonunu önlemeye yönelik kullanılan yöntemlerden biriuygun inhibitör kullanımıdır. Bu amaç doğrultusunda bu çalışmada,4-okso-kinazolin türevi olan uzun karbon zinciri içeren 3 adet katyonikpiridinyum ...
Serkan Öztürk
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Signaling events involved in cytokine and chemokine production induced by secretory phospholipase A2 in human lung macrophages. [PDF]
7openopenGranata F; Frattini A; Loffredo S; Del Prete A; Sozzani S; Marone G; Triggiani M.Granata, F; Frattini, A; Loffredo, S; DEL PRETE, Annalisa; Sozzani, Silvano; Marone, G; Triggiani ...
DEL PRETE A +6 more
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