Results 101 to 110 of about 10,618 (207)
Quinazoline compounds for antitumor treatment
Experimental Oncology, 2023 Summary. Quinazolines are among the most useful heterocyclic compounds due to their diverse chemical reactivity and a wide range of biological activity. Despite a large number of publications devoted to quinazolines and their derivatives, information is presented predominantly regarding the features of the synthesis of these compounds and their ...
openaire +2 more sources
Nature Communications, 2017 Heterocycles are ubiquitous in bioactive compounds and routes to different substitution patterns are important to access the full substrate space.
Felix E. Held +13 more
doaj +1 more source
Synthesis and Reactivity of [1,2,4]Triazolo-annelated Quinazolines
Molecules, 2010 This paper reports the synthesis of phenyl-substituted 2-alkoxy(methylsulfanyl)-1,2,4-triazolo[1,5-a]quinazolines starting from N-cyanoimidocarbonates and substituted hydrazinobenzoic acids as building blocks.
Rashad A. Al-Salahi
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Synthesis and biological evaluation of novel 2-phenylquinazoline-4-amine derivatives:identification of 6-phenyl-8H-benzo[g]quinazolino[4,3-b]quinazolin-8-one as a highly potent inducer of NAD(P)H quinone oxidoreductase 1 [PDF]
, 2016 A novel series of quinazoline compounds (2-14) incorporating biologically active heterocyclic moieties were designed and synthesized. The structure of the newly synthesized compounds was recognized on the basis of elemental analyses, IR, (1)H-NMR, (13)C ...
Abdelaaty A. Shahat +9 more
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Future Journal of Pharmaceutical Sciences, 2015 Background: Molybdenum hydroxylases have been implicated as key oxidative enzymes in some diseases. Methods: Twenty 2-(substituted-thio)-quinazolin-4-one derivatives recently synthesized in our laboratory were examined for their inhibitory activity ...
Hussein I. El-Subbagh +3 more
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Recent advances using [Cp*Co(CO)I2] catalysts as a powerful tool for C-H functionalisation [PDF]
, 2017 Expansion of the synthetic chemists' toolbox is currently a topic of great interest, with successes providing access to novel compounds and more efficient routes towards new and known pharmaceuticals and agrochemicals.
Chirila, Paula G, Whiteoak, Christopher
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Aqueous phase hydration and hydrate acidity of perfluoroalkyl and n:2 fluorotelomer aldehydes [PDF]
, 2010 Perfluoroalkyl aldehydes (PFAlds) and n:2 fluorotelomer aldehydes (FTAlds) are degradation products of precursor compounds that include fluorotelomer alcohols, iodides, acrylates, phosphate esters, and other derivatives, as well as hydrofluorocarbons and
Kaya Forest, Sierra Rayne
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Chiral benzimidazoles as hydrogen bonding organocatalysts [PDF]
, 2015 Several bifunctional organocatalysts bearing the benzimidazole unit have been designed in order to act as bifunctional systems by hydrogen bonding. Chiral 2-aminobenzimidazoles are conformational rigid guanidines able to catalyze enantioselectively ...
Nájera, Carmen, Yus, Miguel
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Microwave assisted synthesis of triazoloquinazolinones and benzimidazoquinazolinones
Beilstein Journal of Organic Chemistry, 2007 BackgroundBenzimidazoquinazolinones and related quinazolines are classes of heterocycles that are of considerable interest because of the diverse range of their biological properties.
Aboul-Fetouh E. Mourad +3 more
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