Results 81 to 90 of about 10,618 (207)

3-[4-(1H-indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, nortopsentin Analogues with antiproliferative activity [PDF]

, 2015
A new series of nortopsentin analogues, in which the imidazole ring of the natural product was replaced by thiazole and the indole unit bound to position 2 of the thiazole ring was substituted by a 7-azaindole moiety, was efficiently synthesized.
Attanzio, A., Barraja, P., Carbone, A., Ciancimino, C., Cirrincione, G., Di Vita, G., Diana, P., Livrea, M., Montalbano, A., Parrino, B., Span\uf2, V., Tesoriere, L.   +11 more
core   +2 more sources

A Convenient One‐Pot CuI‐Catalyzed Procedure for the Synthesis of S‐(N‐Heteroaryl) Thiocarboxylates From N‐Heteroaryl Bromides and Thiobenzoic Acid

ChemistryOpen, Volume 15, Issue 4, April 2026.
A one‐pot two‐step CuI‐catalyzed procedure for the synthesis of S‐(N‐heteroaryl) thiocarboxylates from N‐heteroaryl bromides and thiobenzoic acid was developed, which is highlighted by shorter reaction time, a smaller amount of iodide source and scalability.
Jiamin Pan, Suting Xie, Yong Li, Jiang Wu, Guilong Zhao   +4 more
wiley   +1 more source

Design, Synthesis, and Biological Evaluation of 4-aminoquinazoline Appended-Benzofuran Hybrids as Epidermal Growth Factor Receptor Inhibitors

Proceedings, 2019
Nitrogen-containing heterocycles such as quinazolines and benzofurans have received a great amount of interest in targeted therapies as antitumor drugs [1]. [...]
Marole Maria Maluleka, Malose Jack Mphahlele   +1 more
doaj   +1 more source

Anti-Allergic Cromones Inhibit Histamine and Eicosanoid Release from Activated Human and Murine Mast Cells by Releasing Annexin A1 [PDF]

, 2013
PMCID: PMC3601088This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Ahluwalia, A Mulla, AB Kay, Ajantha Sinniah, AM Lucas, Bernhard Ryffel, C Bandeira-Melo, C Dahl, CD John, CF Schwender, CF Schwender, CP Sung, CP Sung, DS Thomson, E Solito, E Solito, E Wells, EB Cook, Egle Solito, F D'Acquisto, FL Pearce, FN Gavins, FS Ng, G Folkerts, G Galatowicz, J Raud, JD Croxtall, JP Tarayre, JP Tarayre, JP Tarayre, JS Cox, JS Cox, JS Cox, JS Cox, K Kuriyama, L Jenkins, L Wang, M Corbel, M Perretti, M Shichijo, MK Church, NJ Goulding, PJ Barnes, R Sagi-Eisenberg, RH Grace, RJ Rintala, RM Viscardi, Rod J. Flower, RP Hayhoe, S Mattoli, S Murphy, S Pieretti, S Yazid, S Yazid, Samia Yazid, SH Lee, SH Peers, SI Wasserman, SilvaJR Lapa e, SK Bansal, SM Oliani, T Du, T Oka, T Radeau, TC Theoharides, TC Theoharides, TW Evans, Virginia Calder, WM Abraham, WM Abraham, Y Okayama, Y Yang, Y Zuo, YW Chung   +73 more
core   +2 more sources

Comprehensive Analysis of Structure Activity Relationships in Quinoxaline Derivatives Covering Antimicrobial Applications

ChemistrySelect, Volume 11, Issue 14, 13 April 2026.
ABSTRACT Antimicrobial resistance (AMR) has emerged as one of the most critical global health challenges, undermining the clinical efficacy of existing antibiotics and threatening modern therapeutic strategies. The ongoing misuse and overuse of antimicrobial agents have accelerated the evolution of resistant bacterial strains and parasites ...
Subham Kumar Vishwakarma, Fernando Rogério Pavan, Cesar Augusto Roque‐Borda   +2 more
wiley   +1 more source

Design, Synthesis, and Cytotoxicity Evaluation of Novel Indolin-2-One Based Molecules on Hepatocellular Carcinoma HepG2 Cells as Protein Kinase Inhibitors

Molecules
A series of indolinone-based derivatives were designed and synthesized using the hybrid pharmacophoric design approach as cytotoxic kinase inhibitors.
Manal M. Kandeel, Mohamed Kamal AbdElhameid, Mohamed Adel, Muhammad Y. Al-Shorbagy, Ahmed T. Negmeldin   +4 more
doaj   +1 more source

UA94/6/15 Student / Alumni Personal Papers WKU Dorris Hutchinson [PDF]

, 2015
Correspondence and publications created by and about the Dorris Hutchison during her time at Sloan-Kettering ...
WKU Archives
core   +1 more source

AI‐Augmented Iterative Screening of Libraries Against RNA Targets (AISLAR) Boosts Discovery of SAR‐Tractable RNA Binders and Rational Analog Design

Small Science, Volume 6, Issue 4, April 2026.
AI‐augmented iterative screening of libraries against RNA targets (AISLAR) combines fluorescence resonance energy transfer screening, machine learning, and validation by dose response and isothermal titration calorimetry to discover RNA binders. Applied to p53 mRNA motifs, AISLAR identified chemotypes with tractable structure–activity relationships ...
Haruhiko Hattori, Maina Otsu, Koji Imai, Mebuki Narahara, Jiro Kondo, Amiu Shino, Ella Czarina Morishita   +6 more
wiley   +1 more source

Evaluación de los fungicidas proquinazid y tetraconazole en el control de oídio (Erysiphe necator) en vid vinífera (Vitis vinifera L.) [PDF]

, 2015
40 p.El Oídio de la vid, causado por el hongo Erysiphe necator, es una enfermedad que se encuentra en la mayoría de las áreas vitivinícolas del mundo, afectando a todos los órganos herbáceos de la vid, y produciendo graves daños tales como, en la ...
Fuentes Medina, Marcela Ayelen, Lolas Caneo, Mauricio (Prof. Guía), Méndez Muñoz, Raúl Edgardo (Prof. Informante)   +2 more
core  

The importance of mass spectrometric dereplication in fungal secondary metabolite analysis [PDF]

, 2015
Having entered the Genomic Era, it is now evident that the biosynthetic potential of filamentous fungi is much larger than was thought even a decade ago.
Larsen, Thomas Ostenfeld, Nielsen, Kristian Fog   +1 more
core   +2 more sources