Results 11 to 20 of about 56,164 (276)

Artemisinin and Quinoline Hybrid Compounds Inhibit Replication of SARS-CoV-2 In Vitro [PDF]

, 2021
The newly emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cause life-threatening diseases in millions of people worldwide and there is an urgent need for antiviral agents against this infection.
Lutz, Ackermann, Julia, Struwe, Grigoriy , Stepanov, Alexander , Terent\u27ev, Aysun, Çapcı, Lars, Herrmann, Jan, Weber, Jan, Hodek, Yulia , Belyakova, Peter , Radulov, Svetlana, Tsogoeva, Ivan, Yaremenko   +11 more
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Solid-State Photodimerization Reaction with Photosalient Effect and Photophysical and Electrochemical Properties of N‑Methylated 1‑Naphthylvinyl-4-Quinoline

, 2023
Crystal packing-dependent photochemical reactions of several functional olefins have been explored, but not for 1-naphthylvinyl-4-quinoline (NVQ) and analogous N-methylated 1-naphthylvinyl-4-quinoline cation (MNVQ).
Tamil Selvan Kannan (17103019), Subrata Munan (12043032), Goutam Kumar Kole (2131231), Animesh Samanta (1653568), Murugavel Kathiresan (2150164)   +4 more
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Quinoline-Based Photolabile Protection Strategy Facilitates Efficient Protein Assembly

, 2022
Native chemical ligation (NCL) provides a powerful solution to assemble proteins with precise chemical features, which enables a detailed investigation of the protein structure–function relationship.
Yunxue Li, Bei Ding (281309), Qingqing Zhou, Qingqing Zhou (3801922), Zhongneng Zhou (3876583), Ping Wang (42415), Xinliang Liu, Bei Ding, Ping Wang, Farong Ye, Zhongneng Zhou, Xinliang Liu (2827547), Jie Zhao (49409), Siyao Wang, Bingcheng Wei (11954095), Bingcheng Wei, Jie Zhao, Yunxue Li (11334957), Farong Ye (7651112), Siyao Wang (1468693)   +19 more
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Synthesis and biological evaluation of novel quinoline analogs of ketoprofen as multidrug resistance protein 2 (MRP2) inhibitors [PDF]

Iranian Journal of Basic Medical Sciences, 2021
Objective(s): A new series of quinoline analogs of ketoprofen was designed and synthesized as multidrug resistance protein 2 (MRP2) inhibitors using ketoprofen as the lead compounds.Materials and Methods:  The cytotoxic activity of the compounds was ...
Fatemeh Mosafa, Farzin Hadizadeh, Faezeh Fathi, Zahra Eslami Nasab, Tahereh Pourzahed, Sayyed Mohammad Aboutorabzade, Razieh Ghodsi   +6 more
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Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site [PDF]

, 2019
A series of novel isocombretastatin A-4 (isoCA-4) analogs were designed and synthesized by replacing 3,4,5-trimethoylphenyl and isovanillin of isoCA-4 with quinoline and indole moieties, respectively.
Ma, Cong, Zhu, Zheying, Bi, Yi, Yao, Hequan, Sun, Honghao, Xu, Feijie, Li, Wenlong, Shuai, Wen, Xu, Jinyi, Xu, Shengtao   +9 more
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Synthesis of antioxidant and antimicrobial bioactive compounds based on the quinoline-hydrazone and benzimidazole structure

Journal of Advanced Pharmaceutical Technology & Research, 2023
Quinoline and its derivatives are known to have various biological activities such as antibacterial and antioxidant. Therefore, this study aims to synthesize quinoline moiety from isatin and ethyl acetoacetate by Pfitzinger reaction under acidic ...
Antonius Herry Cahyana, Devin Halim, Laely Amaliyah   +2 more
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Identification of human S100A9 as a novel target for treatment of autoimmune disease via binding to quinoline-3-carboxamides.

PLoS Biology, 2009
Despite more than 25 years of research, the molecular targets of quinoline-3-carboxamides have been elusive although these compounds are currently in Phase II and III development for treatment of autoimmune/inflammatory diseases in humans.
Per Björk, Anders Björk, Thomas Vogl, Martin Stenström, David Liberg, Anders Olsson, Johannes Roth, Fredrik Ivars, Tomas Leanderson   +8 more
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Recent advances in functionalized quinoline scaffolds and hybrids—Exceptional pharmacophore in therapeutic medicine

Frontiers in Chemistry, 2023
Quinoline is one of the most common nitrogen-containing heterocycles owing to its fascinating pharmacological properties and synthetic value in organic and pharmaceutical chemistry.
Oluwadunni F. Elebiju, Oluwadunni F. Elebiju, Olayinka O. Ajani, Olayinka O. Ajani, Gbolahan O. Oduselu, Gbolahan O. Oduselu, Temitope A. Ogunnupebi, Temitope A. Ogunnupebi, Ezekiel Adebiyi, Ezekiel Adebiyi, Ezekiel Adebiyi   +10 more
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PERHALIDES OF QUINOLINE. [PDF]

Journal of the American Chemical Society, 1899
n ...
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DataSheet1_Discovery of 2-(4-Acrylamidophenyl)-Quinoline-4-Carboxylic Acid Derivatives as Potent SIRT3 Inhibitors.PDF

, 2022
In discovery of novel SIRT3 inhibitors for the treatment of cancer, a series of 2-(4-acrylamidophenyl)-quinoline-4-carboxylic acid derivatives were designed and synthesized.
Congying Gao (12319886), Lei Zhang (38117), Xueming Li (1397404), Wenli Fan (12319883), Qian Hui (12319880), Lin Zhang (8926), Hongyu Qin (3873835), Liuya Wei (3567596)   +7 more
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