Results 11 to 20 of about 36,400 (237)

Evaluation of the Potential Anti-Inflammatory Effect of a New Coumarin–Quinoline Hybrid in LPS-Induced Neuroinflammation [PDF]

Pharmaceuticals
Background/Objectives: Neuroinflammation is characterized by the sustained activation of neuroglial cells, resulting in the production of cytokines and chemokines. It is associated with neurodegenerative processes. This study aims to assess the potential
Omnia Hamdy Mohamed Shehata, Eman Abdelaziz, Hadeer Ali, Elshaymaa I. Elmongy, Reem Binsuwaidan, Wafaa M. Ibrahim, Sabreen El-Gamasy, Ibrahim El Tantawy El Sayed   +7 more
doaj   +2 more sources

Benzimidazole-Quinoline Hybrids: Synthesis and Antimicrobial Properties [PDF]

Pharmaceuticals
Background: Heterocyclic compounds are particularly important in medicinal chemistry. With a range of therapeutic uses, benzimidazoles and quinolines are both key heterocycles in medicinal chemistry.
Maria Marinescu
doaj   +2 more sources

PERHALIDES OF QUINOLINE. [PDF]

Journal of the American Chemical Society, 1899
n ...
openaire   +2 more sources

Synthesis of antioxidant and antimicrobial bioactive compounds based on the quinoline-hydrazone and benzimidazole structure

Journal of Advanced Pharmaceutical Technology & Research, 2023
Quinoline and its derivatives are known to have various biological activities such as antibacterial and antioxidant. Therefore, this study aims to synthesize quinoline moiety from isatin and ethyl acetoacetate by Pfitzinger reaction under acidic ...
Antonius Herry Cahyana, Devin Halim, Laely Amaliyah   +2 more
doaj   +1 more source

Identification of human S100A9 as a novel target for treatment of autoimmune disease via binding to quinoline-3-carboxamides.

PLoS Biology, 2009
Despite more than 25 years of research, the molecular targets of quinoline-3-carboxamides have been elusive although these compounds are currently in Phase II and III development for treatment of autoimmune/inflammatory diseases in humans.
Per Björk, Anders Björk, Thomas Vogl, Martin Stenström, David Liberg, Anders Olsson, Johannes Roth, Fredrik Ivars, Tomas Leanderson   +8 more
doaj   +1 more source

Recent advances in functionalized quinoline scaffolds and hybrids—Exceptional pharmacophore in therapeutic medicine

Frontiers in Chemistry, 2023
Quinoline is one of the most common nitrogen-containing heterocycles owing to its fascinating pharmacological properties and synthetic value in organic and pharmaceutical chemistry.
Oluwadunni F. Elebiju, Oluwadunni F. Elebiju, Olayinka O. Ajani, Olayinka O. Ajani, Gbolahan O. Oduselu, Gbolahan O. Oduselu, Temitope A. Ogunnupebi, Temitope A. Ogunnupebi, Ezekiel Adebiyi, Ezekiel Adebiyi, Ezekiel Adebiyi   +10 more
doaj   +1 more source

SYNTHESIS OF CERTAIN NOVEL PYRIDOTHIOPYRANOQUINOLINES AS POTENTIAL ANTICANCER AGENTS

Zagazig Journal of Pharmaceutical Sciences, 2006
A series of ethyl 2-substituted aminopyrido [3',2': 5,6] thiopyrano [ 4,3,2-de] quinoline-1-carboxylate (VII)i-viii was obtained by reacting ethyl2-chloropyrido[3',2':5,6] thiopyrano [4,3,2-de] quinoline-1-carboxylate (VIa) with certain aromatic amines ...
Khaled El-Shemy , Osama El-Badry , Sameha Roshdy , Mervat El-Enany , Mohamed Ismail   +4 more
doaj   +1 more source

Ultrasonic treated sludge for accelerating quinoline biodegradation

上海师范大学学报. 自然科学版, 2018
In this work,ultrasound was used for treating sludge,and released organics was used as electron donors for accelerating quinoline biodegradation.Flask experimental results showed that quinoline removal rates are proportional to the biomass of treated and
Wang Youke, Zhang Yuting, Lu Qinyuan, Zhang Chenyuan, Zhang Yongming   +4 more
doaj   +1 more source

Hydrogen-Bonding Interactions in Luminescent Quinoline-Triazoles with Dominant 1D Crystals

Molecules, 2017
Quinoline-triazoles 2-((4-(diethoxymethyl)-1H-1,2,3-triazol-1-yl)methyl)quinoline (1), 2-((4-(m-tolyl)-1H-1,2,3-triazol-1-yl)methyl)quinoline (2) and 2-((4-(p-tolyl)-1H-1,2,3-triazol-1-yl)methyl)quinoline (3) have been prepared with CuAAC click reactions
Shi-Qiang Bai, David James Young, T. S. Andy Hor   +2 more
doaj   +1 more source

Quinolin-3-amine [PDF]

Acta Crystallographica Section E Structure Reports Online, 2012
In the crystal structur of the achiral title compound, C(9)H(8)N(2), N-H⋯N hydrogen bonds connect the mol-ecules into zigzag chains in [100]. Weak inter-molecular N-H⋯π inter-actions further consolidate the crystal packing.
Islor, Arun M., Chandrakantha, B., Shetty, Prakash, Gerber, Thomas, Hosten, Eric, Betz, Richard   +5 more
openaire   +2 more sources