Results 41 to 50 of about 36,400 (237)

SYNTHESIS AND ANTIMICROBIAL EVALUATION OF NOVEL 4-OXOTHIAZOLIDINYL QUINOLINES AND TRIAZOLOQUINOLINES [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 1994
Different thiazolidinone derivatives have been prepared, attached either to 2- or 3-position of quinoline or attached to the 4-position of triazolo[4,3-a] quinoline. The antimicrobial activity of most of the prepared compounds has been studied.
Ola El-Sayed
doaj   +1 more source

Single‐Molecule Characterization of Bacterial Factor‐Dependent Transcription Activation by Rob

Advanced Science, EarlyView.
Factor‐dependent transcription activation is crucial and involves complex interactions between transcription factors, RNA polymerase, and promoter DNA. Using single‐molecule assays, we show that Rob prebinds RNAP to facilitate promoter search and enhances DNA unwinding and promoter escape.
Yuqiong Zhang, Weijing Han, Jing Shi, Lisha Wang, Cuijuan Teng, Wei Lin, Jun Fan, Shuang Wang   +7 more
wiley   +1 more source

A new functional biofilm biocatalyst for the simultaneous removal of dibenzothiophene and quinoline using Rhodococcus rhodochrous and curli amyloid overproducer mutants derived from Cobetia sp. strain MM1IDA2H-1

Biotechnology Reports, 2018
Biocatalyst systems based on biofilms were developed to remove nitrogen and sulfur-containing heterocyclic hydrocarbons using Cobetia sp. strain MM1IDA2H-1 and Rhodococcus rhodochrous. The curli overproducers mutants CM1 and CM4 were derived from Cobetia
M. Alejandro Dinamarca, Johana Eyzaguirre, Patricio Baeza, Paulina Aballay, Christian Canales, Juan Ojeda   +5 more
doaj   +1 more source

Reaction of quinaldine with 4,6-di(tert-butyl)-3-nitro-1,2-benzoquinone. Dependence of the outcome on the reaction conditions and a deeper insight into the mechanism

Heliyon, 2023
Condensation of quinaldine with 4,6-di (tert-butyl)-3-nitro-1,2-benzoquinone results in the formation of 5,7-di (tert-butyl)-2-(quinoline-2-yl)-1,3-tropolone, 5,7-di (tert-butyl)-4-nitro-2-(quinoline-2-yl)-1,3-tropolone, 3,3-dimethyl-2-(5-hydroxy-4-nitro-
Tatyana A. Krasnikova, Yurii A. Sayapin, Inna O. Tupaeva, Eugeny A. Gusakov, Ilya V. Ozhogin, Anton V. Lisovin, Mikhail V. Nikogosov, Oleg P. Demidov, Duong Nghia Bang, Tran Dai Lam, Nguyen Thi Thu Trang, Alexander D. Dubonosov, Vladimir I. Minkin   +12 more
doaj   +1 more source

S100A8/A9‐High Macrophages Activate Intestinal Fibroblasts via mCCL6/hCCL15‐CCR1 Axis to Drive Intestinal Fibrosis in Crohn's Disease

Advanced Science, EarlyView.
S100A8/A9‐high macrophages are markedly enriched in the stenotic intestinal tissue of patients with Crohn's disease. These profibrotic macrophages secrete mCCL6 in a STAT3‐dependent manner. mCCL6 and its human ortholog hCCL15 activate fibroblasts via the CCR1 receptor, thereby driving excessive collagen deposition.
Shu Wang, Jiayun Wang, Junjie Lin, Ziping Ye, Geyujia Zhou, Jingjing Ma, Junjian Sun, Jiang Yu, Yingdi Zhang, Nana Tang, Chunhua Jiao, Xiaojing Zhao, Hongjie Zhang   +12 more
wiley   +1 more source

Quinoline-2-sulfonamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2013
In the title compound, C9H8N2O2S, the sulfamoyl -NH2 group is involved in inter-molecular hydrogen bonding with the sulfonamide O and quinoline N atoms. In the crystal, mol-ecules are linked into dimers via pairs of N-H⋯N hydrogen bonds, forming an R 2 (2)(10) motif.
Joachim Kusz, Maria Nowak, Andrzej Maślankiewicz, Krzysztof Marciniec   +3 more
openaire   +3 more sources

Pd‐Catalyzed Asymmetric Dearomative Heck/Tsuji‐Trost Difunctionalization of Naphthalenes

Advanced Science, EarlyView.
We have developed a palladium‐catalyzed asymmetric dearomative Heck/Tsuji‐Trost 1,4‐difunctionalization reaction of naphthalenes, affording 4‐aminospirocyclohexene oxindole products bearing two remote chiral centers. Through the effect of the newly designed chiral sulfinamide phosphine ligand with large steric hindrance, side reactions are inhibited ...
Long‐Ling Ma, Bing Xu, Junliang Zhang, Zhan‐Ming Zhang   +3 more
wiley   +1 more source

Current developments of metal- and metalloid-based quinoline compounds as leishmanicidal agents

Frontiers in Chemistry
The quinoline moiety represents an important scaffold for the development of leishmanicidal agents. In particular, its hybridization with metal/metalloids has generated highly active compounds that are, in some cases, highly selective against ...
Edgar Del Carpio, Lino Hernández, Vito Lubes, Francisco Jourdan, Hugo Cerecetto, Hugo Cerecetto, Gonzalo Scalese, Gonzalo Scalese, Dinorah Gambino, Angel H. Romero   +9 more
doaj   +1 more source

Quinoline-2-carbaldehyde [PDF]

Acta Crystallographica Section E Structure Reports Online, 2011
The title compound, C(10)H(7)NO, crystallizes with two almost planar mol-ecules (A and B) in the asymmetric unit (r.m.s. deviations = 0.018 and 0.020 Å). In the crystal, the A mol-ecules are linked by weak C-H⋯O inter-actions, thereby generating C(9) [001] chains. The B mol-ecules do not exhibit any directional bonding inter-actions.
Martin O. Onani, William M. Motswainyana
openaire   +3 more sources

Facile synthesis of novel quinolin-8-amine derivatives: crystallographic study, in silico and antifungal investigation

Chemical and Biological Technologies in Agriculture
Background Quinoline, an important nitrogen-containing heterocycle, is frequently found in both natural and synthetic compounds. Numerous quinoline derivatives have been developed as commercial pharmaceuticals and pesticides. Due to quinoline derivatives
Jian-Ying Tong, Li-Jing Min, Na-Bo Sun, Hong-Ke Wu, Shu-Jing Yu, Qiang Bian, Xing-Hai Liu   +6 more
doaj   +1 more source