Increase in Alzheimer's related markers preceeds memory disturbances: Studies in vasopressin-deficient Brattleboro rat [PDF]
Alzheimer's disease (AD) is the most common form of dementia in the elderly. For more effective therapy early diagnostic markers could be beneficial. Therefore we compared one year old rats with adults and examined if changes in possible brain markers of
Bagdy, György +12 more
core
Butyrate ameliorates quinolinic acid-induced cognitive decline in obesity models. [PDF]
Ge X +17 more
europepmc +1 more source
De Novo Biosynthesis of Nicotinamide Adenine Dinucleotide in Escherichia coli : Excretion of Quinolinic Acid by Mutants Lacking Quinolinate Phosphoribosyl Transferase [PDF]
Jerry L. R. Chandler, R.K. Gholson
openalex +1 more source
Neuroprotective effects of a Wnt antagonist in quinolinic acid-induced excitotoxicity in N18D3 cells
Jinsu Hwang +5 more
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De novo NAD+ synthesis is ineffective for NAD+ supply in axenically cultured Caenorhabditis elegans
To secure an adequate nicotinamide adenine dinucleotide (NAD+) supply for survival, organisms typically rely on two complementary mechanisms: the de novo synthesis pathway and the salvage pathway.
Shihao Zhu +6 more
doaj +1 more source
Cerebrospinal fluid quinolinic acid is strongly associated with delirium and mortality in hip-fracture patients. [PDF]
Watne LO +20 more
europepmc +1 more source
Exploring the neuroprotective effects of montelukast on brain inflammation and metabolism in a rat model of quinolinic acid-induced striatal neurotoxicity. [PDF]
Tassan Mazzocco M +9 more
europepmc +1 more source
Background Tryptophan, an essential precursor metabolite within the kynurenine pathway, has been implicated in the neurobiological mechanisms underlying both schizophrenia and associated suicidality. Despite this link, the lack of validated biomarkers to
Yi Yin +12 more
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