Results 81 to 90 of about 816,736 (162)

Methods of preparation and biological activity of quinolinic acid and derivatives [PDF]

, 2003
In 1981 2,3-pyridine dicarboxylic acid (quinolinic acid) was discovery to be a selective agonist for the N-methyl -D-aspartic acid (NMDA) receptor.
Amarante, Giovanni Wilson, Almeida, Mauro Vieira de, Le Hyaric, Mireille, Cardoso, Sílvia Helena, Souza, Marcus Vinícius Nora de, Hyaric, Mireille Le   +5 more
core   +1 more source

Kynurenine pathway metabolites are increased in inflammatory depression and decrease with omega-3 treatment

Brain, Behavior, & Immunity - Health
Activation of the kynurenine pathway (KP) with resulting accumulation of neuroactive metabolites may be a downstream pathophysiological mechanism of inflammatory depression.
Jesper Lindahl, Gustav Söderberg Veibäck, Klara Suneson, Wilma Blanking, Johanna Tjernberg, Darya Ståhl, Åsa Wiman, Filip Ventorp, Sophie Erhardt, Daniel Lindqvist   +9 more
doaj   +1 more source

Metabolic signatures and a diagnostic model for citrin deficiency based on urinary organic acids

Clinical and Translational Medicine
Purpose This study aimed to characterise urinary organic acid profiles in Neonatal Intrahepatic Cholestasis caused by Citrin Deficiency (NICCD) and develop a diagnosis model to distinguish NICCD patients from those in the non‐specific metabolic ...
Peiyao Wang, Peichun Chen, Xinjie Yang, Ziyan Cen, Yu Zhang, Qimin He, Benqing Wu, Xinwen Huang   +7 more
doaj   +1 more source

Time course of the neuroprotective effect of transplantation on quinolinic acid-induced lesions of the striatum

, 1995
Injection of quinolinic acid in the rat striatum mimics neurochemical changes observed in Huntington's disease. We previously demonstrated that intrastriatal transplantation of fetal striatum or gelfoam protects against toxicity induced by a subsequent ...
Przedborski, S., Gash, Don Marshall, Levivier, Marc   +2 more
core   +1 more source

Quinolinic acid-induced lesions of the rat striatum: quantitative autoradiographic binding assessment.

, 1998
Injection of the excitatory amino-acid analog quinolinic acid into the striatum of rats produces neuropathological and neurochemical alterations that are reminiscent of those observed in Huntington's disease. In the present study, we evaluated quinolinic
Levivier, M., Przedborski, S.
core   +2 more sources

Oregano essential oil enhanced body weight and well-being by modulating the HPA axis and 23-nordeoxycholic acid of cecal microbiota in Holstein steers under cold stress

Animal Microbiome
Background Prolonged exposure to cold stress in cattle increases basal energy consumption and impedes optimal production. Consequently, herds require adequate attention during cold, extended winters to alleviate cold stress and maintain profitability ...
Yongliang Huang, Siyu Cheng, Jinping Shi, Pengjia He, Yue Ma, Xu Zhang, Yongzhi Cao, Zhaomin Lei   +7 more
doaj   +1 more source

Effects of direct-fed microbial supplement on ruminal and plasma metabolome of early-lactation dairy cows: Untargeted metabolomics approach

Journal of Dairy Science
: We examined the effects of 2 multispecies direct-fed microbial (DFM) supplements on ruminal and plasma metabolome of early-lactation dairy cows using a high-coverage untargeted metabolomics approach. A total of 45 multiparous Holstein cows (41 ± 7 DIM)
A.O. Oyebade, G.A. Taiwo, Modoluwamu Idowu, T. Sidney, O. Queiroz, A.T. Adesogan, D. Vyas, I.M. Ogunade   +7 more
doaj   +1 more source

QUINOLINIC ACID METABOLISM

Journal of Biological Chemistry, 1949
L.M. Henderson, G.B. Ramasarma
  +5 more sources

Estudo fitoquímico, toxicológico e dos efeitos neuroprotetor e tipo antidepressivo do extrato aquoso de Aloysia gratissima (Gill et Hook) Troncoso (erva santa) [PDF]

, 2011
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2011Aloysia gratissima é uma planta utilizada para tratar sintomas de doenças relacionadas principalmente
Zeni, Ana Lúcia Bertarello
core  

Mild and effective N-phthaloylation of amino acids

, 2004
In the present work various free amino acids, including tryptophan and tyrosine, were effectively N-phthaloylated under reduced pressure and at lower temperature.
Liu, Z, 曾庆乐, Zeng, Q, Li, B, Wang, F   +4 more
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