Results 81 to 90 of about 7,875 (206)
Comparison of the neuroprotective potential of theanine and minocycline [PDF]
, 2010 Stroke is one of the most common causes of disability and death worldwide. The most commonly experienced stroke in the clinical setting is focal ischaemia in which the middle cerebral artery (MCA) is occluded and leads to a complex series of various ...
Mpofu, Tariro Ann-Maureen
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Effects of ethylenediamine – a putative GABA-releasing agent – on rat hippocampal slices and neocortical activity in vivo [PDF]
, 2010 The simple diamine diaminoethane (ethylenediamine, EDA) has been shown to activate GABA receptors in the central and peripheral nervous systems, partly by a direct action and partly by releasing endogenous GABA.
Addae, J.I., Lui, C., Stone, T.W.
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ChemMedChem, Volume 21, Issue 7, 14 April 2026.A SAR study led to the identification of new 2‐phenylquinoline‐based derivatives that exhibit anti‐Severe Acute Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) activity by acting as ATP‐competitive inhibitors of nonstructural protein 13 (nsp13) helicase.
Giada Cernicchi +24 more
wiley +1 more source
The crystal structure of Fe₄S₄ quinolinate synthase unravels an enzymatic dehydration mechanism that uses tyrosine and a hydrolase-type triad. [PDF]
, 2014 International audienceQuinolinate synthase (NadA) is a Fe4S4 cluster-containing dehydrating enzyme involved in the synthesis of quinolinic acid (QA), the universal precursor of the essential nicotinamide adenine dinucleotide (NAD) coenzyme.
Amara, Patricia +6 more
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Journal of Dairy Science: We examined the effects of 2 multispecies direct-fed microbial (DFM) supplements on ruminal and plasma metabolome of early-lactation dairy cows using a high-coverage untargeted metabolomics approach. A total of 45 multiparous Holstein cows (41 ± 7 DIM)
A.O. Oyebade +7 more
doaj +1 more source
Hyperammonemia-induced toxicity for the developing central nervous system [PDF]
, 2007 In pediatric patients, hyperammonemia can be caused by various acquired or inherited disorders such as urea cycle deficiencies or organic acidemias. The brain is much more susceptible to the deleterious effects of ammonium during development than in ...
Braissant, O., Cagnon, L.
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Animal MicrobiomeBackground Prolonged exposure to cold stress in cattle increases basal energy consumption and impedes optimal production. Consequently, herds require adequate attention during cold, extended winters to alleviate cold stress and maintain profitability ...
Yongliang Huang +7 more
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Cerebrospinal Fluid Biomarkers for Huntington's Disease. [PDF]
, 2016 Cerebrospinal fluid (CSF) is enriched in brain-derived components and represents an accessible and appealing means of interrogating the CNS milieu to study neurodegenerative diseases and identify biomarkers to facilitate the development of novel ...
Byrne, LM, Wild, EJ
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, 1951 The field under review is growing so rapidly that it is impossible to cover more than a sampling of recent papers in the allotted space. Important subjects such as the genetics and chemistry of viruses and certain topics in bacterial genetics have had ...
Horowitz, N. H., Mitchell, H. K.
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Short-term oral atrazine exposure alters the plasma metabolome of male C57BL/6 mice and disrupts α -linolenate, tryptophan, tyrosine and other major metabolic pathways [PDF]
, 2014 Overexposure to the commonly used herbicide atrazine (ATR) affects several organ systems, including the brain. Previously, we demonstrated that short-term oral ATR exposure causes behavioral deficits and dopaminergic and serotonergic dysfunction in the ...
Filipov, Nikolay M. +4 more
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