Results 91 to 100 of about 880,028 (202)

Hesperidin Plays Neuroprotective Effects Against Quinolinic Acid in Human SH-SY5Y Cells: Focusing on ROS Levels and Cell Cycle Arrest [PDF]

open access: yes
Background and objectives: In some neurodegenerative diseases, an aberrant accumulation of quinolinic acid is frequently associated with the loss of nerve cells and a condition known as neuritis.
Emad Azimi   +4 more
core   +2 more sources

Chronic Intrastriatal Dialytic Administration of Quinolinic Acid Produces Selective Neural Degeneration

open access: yes, 1993
The excitotoxic hypothesis of Huntington's disease pathogenesis suggests that selective striatal neuronal loss results from excessive activation of striatal excitatory amino acid receptors.
Albin, Roger L.   +3 more
core   +1 more source

Mild and effective N-phthaloylation of amino acids

open access: yes, 2004
In the present work various free amino acids, including tryptophan and tyrosine, were effectively N-phthaloylated under reduced pressure and at lower temperature.
Liu, Z   +4 more
core  

Replacement of dietary saturated fatty acids by trans fatty acids lowers serum HDL cholesterol and impairs endothelial function in healthy men and women [PDF]

open access: yes, 2001
We tested whether trans fatty acids and saturated fatty acids had different effects on flow-mediated vasodilation (FMD), a risk marker of coronary heart disease (CHD). Consumption of trans fatty acids is related to increased risk of CHD, probably through
Roos, N.M., de, Katan, M.B., Bots, M.L.
core  

Quantitative assessment of quinolinic acid-induced striatal toxicity in rats using radioligand binding assays.

open access: yes, 1994
To validate specific, sensitive and quantitative markers of the rat model of Huntington's disease produced by the intrastriatal injection of quinolinic acid, we used striatal homogenate binding assays for [3H]MK-801-labelled N-methyl-D-aspartate ...
Levivier, M.   +5 more
core   +1 more source

Insights from LC-MS-based cerebrospinal fluid metabolomics in tuberculous meningitis. [PDF]

open access: yesFront Mol Biosci
Plaatjie ON   +3 more
europepmc   +1 more source

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