Results 1 to 10 of about 75,013 (302)

Impact of Quinolone Prophylaxis on Spontaneous Bacterial Peritonitis and Mortality in Cirrhosis Patients: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials [PDF]

JGH Open
Background Cirrhosis is a major global health concern due to its progressive nature and high risk of complications, including spontaneous bacterial peritonitis (SBP), which significantly increases mortality. Quinolone antibiotics, especially norfloxacin,
Ajay Malvi, Nipun Verma, Mahalaqua Nazli Khatib, Subbulakshmi Ganesan, Mandeep Kaur, Manish Srivastava, Amit Barwal, G. V. Siva Prasad, Pranchal Rajput, Rukshar Syed, Kamal Kundra, Kratika Sharma, Diptismitha Jena, Frederick Sidney Correa, Abhinav Rathour, Ganesh Bushi, Rachana Mehta, Sanjit Sah, Prakasini Satapathy, Shilpa Gaidhane, Muhammed Shabil, Hashem Abu Serhan   +21 more
doaj   +2 more sources

2002–2022 Quinolone Resistance in Escherichia coli of Swine in Mainland China: A Meta-Analysis [PDF]

Veterinary Sciences
Swine have emerged as significant reservoirs of antibiotic-resistant strains and genes. To establish a sound rationale for applying quinolone antibiotics in the swine industry, a meta-analysis was performed on the resistance rate of swine-derived ...
Xuelin Long, Shujun Liu, Runmin Kang, Yue Sun, Mingyue Tian, Lijun Zhao, Changwei Lei, Hongning Wang, Xin Yang   +8 more
doaj   +2 more sources

Quinolone Antibiotics: Resistance and Therapy

Infection and Drug Resistance, 2023
The clinical application of quinolone antibiotics is particularly extensive. In addition to their high efficiency in infectious diseases, the treatment process brings multiple hidden dangers or side effects.
Kai Tang, Heng Zhao
semanticscholar   +1 more source

Quinolone: a versatile therapeutic compound class

Molecular diversity, 2022
The discovery of nalidixic acid is one pinnacle in medicinal chemistry, which opened a new area of research that has led to the discovery of several life-saving antimicrobial agents (generally referred to as fluoroquinolones) for over decades.
Phelelisiwe S. Dube, L. Legoabe, Richard M. Beteck   +2 more
semanticscholar   +1 more source

Detection of gyrA and parC Mutations and Prevalence of Plasmid-Mediated Quinolone Resistance Genes in Klebsiella pneumoniae

Infection and Drug Resistance, 2021
Background and Aim Recently, the extensive use of quinolones led to increased resistance to these antimicrobial agents, with different rates according to the organism and the geographical region. The aim of this study was to detect the resistance rate of
S. Kareem, Israa M. S. Al-Kadmy, Saba S. Kazaal, A. M. Mohammed Ali, Sarah N. Aziz, Rabab R. Makharita, Abelazeem M Algammal, Salim Al-Rejaie, T. Behl, G. Batiha, M. El-Mokhtar, H. Hetta   +11 more
semanticscholar   +1 more source

Molecular investigation of quinolone-resistant genes among clinical Staphylococcus aureus isolates in Babylon hospitals

Medical Journal of Babylon, 2023
Background: Staphylococcus aureus is considered an essential etiological factor in several human infections. Although fluoroquinolones are typically used to treat these illnesses, a growing average level of resistance to these medications has been found ...
Emad Noman Hassan Hamza, Suaad Abid Fazaa   +1 more
doaj   +1 more source

Mutational Diversity in the Quinolone Resistance-Determining Regions of Type-II Topoisomerases of Salmonella Serovars

Antibiotics, 2021
Quinolone resistance in bacterial pathogens has primarily been associated with mutations in the quinolone resistance-determining regions (QRDRs) of bacterial type-II topoisomerases, which are DNA gyrase and topoisomerase IV. Depending on the position and
A. Shaheen, A. Tariq, M. Iqbal, O. Mirza, A. Haque, T. Walz, Moazur Rahman   +6 more
semanticscholar   +1 more source

Synthesis and molecular docking studies of some novel Schiff bases incorporating 6-butylquinolinedione moiety as potential topoisomerase IIβ inhibitors [PDF]

Royal Society Open Science, 2018
A series of novel pyranoquinolinone-based Schiff's bases were designed and synthesized. They were evaluated for topoisomerase IIβ (TOP2B) inhibitory activity, and cytotoxicity against breast cancer cell line (MCF-7) for the development of novel ...
Hany M. Hassanin, Rabah A. T. Serya, Wafaa R. Abd Elmoneam, Mai A. Mostafa   +3 more
doaj   +1 more source

Synthesis of Quinolones and Zwitterionic Quinolonate Derivatives with Broad-Spectrum Antibiotic Activity

Pharmaceuticals, 2022
Quinolones are one of the most extensively used therapeutic families of antibiotics. However, the increase in antibiotic-resistant bacteria has rendered many of the available compounds useless.
Beatriz Suay-García, Jose-Ignacio Bueso-Bordils, Gerardo Antón-Fos, María-Teresa Pérez-Gracia, Antonio Falcó, Pedro Alemán-López   +5 more
doaj   +1 more source

Development of ciprofloxacin sensor using iron-doped graphitic carbon nitride as transducer matrix: Analysis of ciprofloxacin in blood samples

Journal of Electrochemical Science and Engineering, 2021
In the present work, we have synthesized an iron-decorated graphitic carbon nitride (Fe@g-C3N4) composite and employed it for electrochemical sensing of ciprofloxacin (CFX).
Hattna Shivarudraiah Vedhavathi, Ballur Prasanna Sanjay , Mahesh Basavaraju, Beejaganahalli Sangameshwara Madhukar, Ningappa Kumara Swamy   +4 more
doaj   +1 more source