Quinolone Resistance in Gallibacterium anatis Determined by Mutations in Quinolone Resistance-Determining Region [PDF]
Antibiotics, 2023 Control of the important pathogen, Gallibacterium anatis, which causes salpingitis and peritonitis in poultry, relies on treatment using antimicrobial compounds.
Kasper Rømer Villumsen +4 more
doaj +3 more sources
Implicación de diversos mecanismos de resistencia a quinolonas en bacilos Gram-negativos: Diseño de una nueva fluoroquinolona [PDF]
, 2008 [spa] DE LA TESIS: Desde la aparición de las quinolonas, las resistencias bacterianas a las mismas han evolucionado de forma paralela. Conforme han ido apareciendo nuevas moléculas con mayor capacidad bactericida y mejores parámetros farmacodinámicos ...
Sánchez Céspedes, Javier
core +6 more sources
Assessment of the genotoxicity of quinolone and fluoroquinolones contaminated soil with the Vicia faba micronucleus test [PDF]
, 2012 The genotoxicity of quinolone and fluroquinolones was assessed using the micronucleus (MN) test on Viciafaba roots by direct contact exposure to a solid matrix.
Khadra, Ahmed +20 more
core +1 more source
Quinolone-3-amidoalkanol: A New Class of Potent and Broad-Spectrum Antimicrobial Agent
, 2023 Herein, we describe 39 novel quinolone compounds bearing a hydrophilic amine chain and varied substituted benzyloxy units. These compounds demonstrate broad-spectrum activities against acid-fast bacterium, Gram-positive and -negative bacteria, fungi, and
Digby F. Warner (848178) +15 more
core +1 more source
Hot-spot consensus of fluoroquinolone-mediated DNA cleavage by gram-negative and gram-positive type II DNA topoisomerases [PDF]
, 2007 Bacterial DNA gyrase and topoisomerase IV are selective targets of fluoroquinolones. Topoisomerase IV versus gyrase and Gram-positive versus Gram-negative behavior was studied based on the different recognition of DNA sequences by topoisomerase ...
GIARETTA G +15 more
core +1 more source
Antibiotics, 2020 The introduction of antimicrobial residues in the food chain has a significant impact on human health. An innovative solution to avoid their presence in meat is the adaptation of current control methods for use with in vivo matrixes. Thus, the aim was to
María Jesús Serrano +11 more
doaj +1 more source
Synthesis and Anti-Leishmanial Properties of Quinolones Derived from Zanthosimuline
Molecules, 2022 Quinoline derivatives and especially quinolones are considered as privileged structures in medicinal chemistry and are often associated with various biological properties. We recently isolated a series of original monoterpenyl quinolones from the bark of
Gwenaëlle Jézéquel +8 more
doaj +1 more source
, 2019 Quinolones are the second most common antibiotic class associated with drug-induced allergic reactions, but data on quinolone allergy are scarce. This review article discusses the available evidence on quinolone allergy, including prevalence, risk ...
Lewis, Susan J +5 more
core +2 more sources
Word-based GWAS harnesses the rich potential of genomic data for E. coli quinolone resistance
Frontiers in Microbiology, 2023 Quinolone resistance presents a growing global health threat. We employed word-based GWAS to explore genomic data, aiming to enhance our understanding of this phenomenon.
Negin Malekian +5 more
doaj +1 more source
Crystal structure of ethyl 8-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylate
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the title compound, C12H10ClNO3, the asymmetric unit comprises two independent molecules, and the dihedral angle between the least-square planes of the quinoline ring systems of these molecules is 73.30 (5)°.
Yoshinobu Ishikawa, Nanako Yoshida
doaj +1 more source