Update on quinolone-containing rescue therapies for Helicobacter pylori infection
World Journal of Gastroenterology, 2020 Third generation of quinolones, such as levofloxacin and moxifloxacin, -containing regimens are often used in second-line or rescue treatment of Helicobacter pylori infection.
H. Mori, Hidekazu Suzuki
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Crystal structure of ethyl 8-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylate
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the title compound, C12H10ClNO3, the asymmetric unit comprises two independent molecules, and the dihedral angle between the least-square planes of the quinoline ring systems of these molecules is 73.30 (5)°.
Yoshinobu Ishikawa, Nanako Yoshida
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Omadacycline Is Highly Active In Vitro against Mycoplasma genitalium
Microbiology Spectrum, 2022 Here, we performed in vitro susceptibility testing on 10 Mycoplasma genitalium isolates against omadacycline, minocycline, tetracycline, doxycycline, moxifloxacin, levofloxacin, and azithromycin.
Ken B. Waites +4 more
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Enhancement of radiosensitivity by the novel anticancer quinolone derivative vosaroxin in preclinical glioblastoma models [PDF]
, 2017 Purpose: Glioblastoma multiforme (GBM) is the most aggressive brain tumor. The activity of vosaroxin, a first-in-class anticancer quinolone derivative that intercalates DNA and inhibits topoisomerase II, was investigated in GBM preclinical models as a ...
Colapietro, Alessandro +11 more
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The Pseudomonas Quinolone Signal (PQS): Not Just for Quorum Sensing Anymore
Frontiers in Cellular and Infection Microbiology, 2018 The Pseudomonas quinolone signal (PQS) has been studied primarily in the context of its role as a quorum-sensing signaling molecule. Recent data suggest, however, that this molecule may also function to mediate iron acquisition, cytotoxicity, outer ...
Jinshui Lin +3 more
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Periodontology 2000, EarlyView., 2023 Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis +5 more
wiley +1 more source
Memorias do Instituto Oswaldo Cruz, 2004 The evaluation of new antimalarial agents using older methods of monitoring sensitivity to antimalarial drugs are laborious and poorly suited to discriminate stage-specific activity.
Carmen E Contreras +6 more
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In vitro Antibacterial Activity of Vitamin C and in Combination with Ciprofloxacin against Uropathogenic Escherichia coli [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: Multidrug Resistant (MDR) bacteria have become a major cause for concern; there has been limited success in the search for newer antibiotics. The search for options has led researchers to vitamin C, an unlikely ally.
Rohan Jacob Verghese +2 more
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Discovery of (S)-3′-hydroxyblebbistatin and (S)-3′-aminoblebbistatin : polar myosin II inhibitors with superior research tool properties [PDF]
, 2017 In search of myosin II inhibitors with superior research tool properties, a chemical optimization campaign of the blebbistatin scaffold was conducted in this paper. (S)-Blebbistatin is the best known small-molecule inhibitor of myosin II ATPase activity.
Bracke, Marc +6 more
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The small quinolone derived compound HT61 enhances the effect of tobramycin against Pseudomonas aeruginosa in vitro and in vivo. [PDF]
, 2020 HT61 is a small quinolone-derived compound previously demonstrated to exhibit bactericidal activity against gram-positive bacteria including methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA). When
Amison, RT +6 more
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