Results 11 to 20 of about 29,062 (270)
On the Nitration of Quinoxalines (Addendum)
Chemical and Pharmaceutical Bulletin, 1960 2-Hydroxyquinoxaline was nitrated with potassium nitrate in conc. sulfuric acid and formed 2-hydroxy-6-nitroquinoxaline, m.p. 306°, in 77% yield. This was treated with dimethyl sulfate and 1-methyl-2-oxo-6-nitro-1, 2-dihydroquinoxaline, m.p. 213°, was obtained, which was also prepared by the condensation of 1-methylamino-2-amino-4-nitrobenzene with ...
Hirotaka Otomasu, Kei Yoshida
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Quinoxaline-2-carbonitrile [PDF]
Acta Crystallographica Section E Structure Reports Online, 2009 In the title compound, C9H5N3, the quinoxaline ring is essentially planar, with a maximum deviation of 0.012 (1) Å. Short intermolecular distances between the centroids of the 2,3-dihydropyrazine and benzene rings [3.6490 (5) Å] indicate the existence of π⋯π interactions.
Hoong‐Kun Fun +4 more
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Recent Updates on the Synthesis of Bioactive Quinoxaline-Containing Sulfonamides
Applied Sciences, 2021 Quinoxaline is a privileged pharmacophore that has broad-spectrum applications in the fields of medicine, pharmacology and pharmaceutics. Similarly, the sulfonamide moiety is of considerable interest in medicinal chemistry, as it exhibits a wide range of
Ali Irfan +7 more
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Neutron scattering from a coordination polymer quantum paramagnet [PDF]
, 2006 Inelastic neutron scattering measurements are reported for a powder sample of the spin-1/2 quantum paramagnet $\rm Cu(Quinoxaline)Br_2$. Magnetic neutron scattering is identified above an energy gap of 1.9 meV.
B. D. Lewis +13 more
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Alkoxyallene‐Based LANCA Three‐Component Synthesis of 1,2‐Diketones, Quinoxalines, and Unique Isoindenone Dimers and a Computational Study of the Isoindenone Dimerization [PDF]
, 2020 A series of β‐alkoxy‐β‐ketoenamides was prepared by the well‐established LANCA three‐component reaction of lithiated 1‐(2‐trimethylsilylethoxy)‐substituted allenes, nitriles, and α,β‐unsaturated carboxylic acids.
Bera M. K. +6 more
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Heterocyclic Communications, 2023 Quinoxalines are a family of nitrogen-based heterocyclic compounds that have garnered much interest because of their wide range of applications. 2,3-Dichloroquinoxaline is an aromatic molecule that frequently serves as a synthetic intermediate in ...
El-Gaby Mohamed S. A. +4 more
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Biotransformation of quinoxaline by Streptomyces badius [PDF]
Letters in Applied Microbiology, 1996 Quinoxaline, a mutagenic azaarene produced in foods during cooking, was added to cultures of Streptomyces badius ATCC 39117. After 24 h, the cultures were extracted with ethyl acetate. Two major metabolites were purified by liquid chromatography and identified by mass spectrometry and nuclear magnetic resonance spectroscopy as 3,4-dihydro-2(1H ...
Sutherland, J. B. +3 more
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Synthesis, Characterization and Protonation Behavior of Quinoxaline-Fused Porphycenes
Molecules, 2017 9,10-Quinoxaline-fused porphycenes 1a-H2 and 1b-H2 were synthesized by intramolecular McMurry coupling. As a result of the annulation of the quinoxaline moiety on the porphycene skeleton, 1a-H2 and 1b-H2 display absorption and fluorescence in the near ...
Daiki Kuzuhara +5 more
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7,8-Dimethyl-11H-indeno[1,2-b]quinoxalin-11-one
IUCrData, 2021 In the title compound, C17H12N2O, the mean planes of the indene ring and quinoxaline system (r.m.s. deviations = 0.0131 and 0.0082 Å) are approximately parallel to one another, making a dihedral angle of 1.2 (5)°.
Lin Chen, Jin Hu, Hong-Shun Sun
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Molecules, 2014 We report the synthesis and antimalarial activities of eighteen quinoxaline and quinoxaline 1,4-di-N-oxide derivatives, eight of which are completely novel. Compounds 1a and 2a were the most active against Plasmodium falciparum strains.
Ana Gil +7 more
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