Results 11 to 20 of about 29,559 (250)

Quinoxaline: A comprehension of current pharmacological advancement in medicinal chemistry

open access: yesEuropean Journal of Medicinal Chemistry Reports, 2022
Quinoxaline is a fused heterocycle ring template present in diverse pharmacophore and widely used in medicinal chemistry. Owing to its vast pharmaceutical profile, several quinoxalines analogous displayed their distinct pharmacological activities. In the
Suresh Kumar Suthar   +4 more
doaj   +2 more sources

Recent Updates on the Synthesis of Bioactive Quinoxaline-Containing Sulfonamides

open access: yesApplied Sciences, 2021
Quinoxaline is a privileged pharmacophore that has broad-spectrum applications in the fields of medicine, pharmacology and pharmaceutics. Similarly, the sulfonamide moiety is of considerable interest in medicinal chemistry, as it exhibits a wide range of
Ali Irfan   +7 more
doaj   +2 more sources

Quinoxaline Derivatives as Antiviral Agents: A Systematic Review

open access: yesMolecules, 2020
Background: In recent decades, several viruses have jumped from animals to humans, triggering sizable outbreaks. The current unprecedent outbreak SARS-COV-2 is prompting a search for new cost-effective therapies to combat this deadly pathogen.
Marc Montana   +3 more
doaj   +2 more sources

Push–Pull Derivatives Based on 2,4′-Biphenylene Linker with Quinoxaline, [1,2,5]Oxadiazolo[3,4-B]Pyrazine and [1,2,5]Thiadiazolo[3,4-B]Pyrazine Electron Withdrawing Parts

open access: yesMolecules, 2022
A series of novel V-shaped quinoxaline, [1,2,5]oxadiazolo[3,4-b]pyrazine and [1,2,5]thiadiazolo[3,4-b]pyrazine push–pull derivatives with 2,4′-biphenylene linker were designed and their electrochemical, photophysical and nonlinear optical properties were
Egor V. Verbitskiy   +7 more
doaj   +2 more sources

Quinoxaline derivatives as attractive electron-transporting materials

open access: yesBeilstein Journal of Organic Chemistry, 2023
This review article provides a comprehensive overview of recent advancements in electron transport materials derived from quinoxaline, along with their applications in various electronic devices. We focus on their utilization in organic solar cells (OSCs)
Zeeshan Abid   +5 more
doaj   +2 more sources

Eco-friendly approach to access of quinoxaline derivatives using nanostructured pyrophosphate Na2PdP2O7 as a new, efficient and reusable heterogeneous catalyst

open access: yesBMC Chemistry, 2020
In the present study, we report the synthesis of various quinoxaline derivatives from direct condensation of substituted aromatic 1,2-diamine with 1,2-dicarbonyl catalyzed by nanostructured pyrophosphate Na2PdP2O7 as a new highly efficient ...
Karim Dânoun   +4 more
doaj   +2 more sources

Cinnamil- and Quinoxaline-Derivative Indicator Dyes for Detecting Volatile Amines in Fish Spoilage

open access: yesMolecules, 2019
Colorimetric indicators are versatile for applications such as intelligent packaging. By interacting with food, package headspace, and/or the ambient environment, color change in these indicators can be useful for reflecting the actual quality and/or ...
Xiaoyu Luo, Loong-Tak Lim
doaj   +2 more sources

Design, Synthesis, and Biological Evaluation of Novel Thiazolidinone-Containing Quinoxaline-1,4-di-N-oxides as Antimycobacterial and Antifungal Agents [PDF]

open access: goldFrontiers in Chemistry, 2020
Tuberculosis and fungal infections can pose serious threats to human health. In order to find novel antimicrobial agents, 26 novel quinoxaline-1,4-di-N-oxides containing a thiazolidinone moiety were designed and synthesized, and their antimycobacterial ...
Heying Zhang   +9 more
openalex   +2 more sources

Design and Synthesis of New Quinoxaline Derivatives as Anticancer Agents and Apoptotic Inducers

open access: yesMolecules, 2019
The quinoxaline scaffold is a promising platform for the discovery of active chemotherapeutic agents. Three series of quinoxaline derivatives were synthesized and biologically evaluated against three tumor cell lines (HCT116 human colon carcinoma, HepG2,
Aliya M. S. El Newahie   +5 more
doaj   +2 more sources

Chemistry and pharmacological diversity of quinoxaline motifs as anticancer agents

open access: yesActa Pharmaceutica, 2019
Surpassing heart diseases, cancer is taking the lead as the deadliest disease because of its fast rate of spreading in all parts of the world. Tireless commitment to searching for novel therapeutic medicines is a worthwhile adventure in synthetic ...
Ajani Olayinka O.   +5 more
doaj   +2 more sources

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