Results 11 to 20 of about 25,177 (318)
Anticancer, anti-inflammatory and analgesic activities of aminoalcohol-based quinoxaline small molecules [PDF]
Acta Cirúrgica BrasileiraPurpose: Bioactive molecules are relevant to fight cancer and associated conditions. Quinoxaline is a privileged N-heterocycle, notably as anticancer agents.
Jannyely Moreira Neri +9 more
doaj +2 more sources
Multicomponent and One‐pot Syntheses of Quinoxalines
Advanced Synthesis and Catalysis, 2021 Thomas J J Müller
exaly +2 more sources
Chemistry, 2021 Of the utmost importance of chirality in organic compounds and drugs, the present work reports structure-chirality relationship of three steroidal quinoxalines, which were synthesised by condensing diaminobenzenes with cholestenone.
Rashid Mehmood +4 more
doaj +1 more source
Recent advances in the transition-metal-free synthesis of quinoxalines
RSC Advances, 2021 Quinoxalines, also known as benzo[a]pyrazines, constitute an important class of nitrogen-containing heterocyclic compounds as a result of their widespread prevalence in natural products, biologically active synthetic drug candidates, and optoelectronic ...
Biplob Borah, L. R. Chowhan
semanticscholar +1 more source
National Science Open, 2023 : Synthetic N-heterocyclic compounds, such as quinoxalines, have shown a crucial role in pharmaceutical as well as food and dye industries. However, the traditional synthesis toward N-heterocycles relies on multistep energy and cost-intensive non ...
Yu Feng +6 more
doaj +1 more source
ACS Omega, 2021 Catalyst-free photoinduced processes in aqueous medium represent significant advancement toward development of green and sustainable pathways in organic synthesis.
D. Sarma +4 more
semanticscholar +1 more source
Journal of Chemistry, 2021 4,5-Dihydropyrrolo [1,2-a]quinoxalines are interesting druggable scaffolds, with multifaceted biological properties, including anticancer properties targeting the G protein-coupled estrogen receptor 1 (GPER).
Gabriele Carullo +3 more
doaj +1 more source
On the Nitration of Quinoxalines (Addendum)
Chemical and Pharmaceutical Bulletin, 1960 2-Hydroxyquinoxaline was nitrated with potassium nitrate in conc. sulfuric acid and formed 2-hydroxy-6-nitroquinoxaline, m.p. 306°, in 77% yield. This was treated with dimethyl sulfate and 1-methyl-2-oxo-6-nitro-1, 2-dihydroquinoxaline, m.p. 213°, was obtained, which was also prepared by the condensation of 1-methylamino-2-amino-4-nitrobenzene with ...
Hirotaka Otomasu, Kei Yoshida
openalex +4 more sources
Docking Applied to the Study of Inhibitors of c-Met Kinase [PDF]
, 2012 Quinoxaline derivatives were studied as inhibitors of c-Met kinase, a receptor associated with high tumor grade and poor prognosis in a number of human cancers.
Luciana Gavernet +2 more
core +8 more sources
Bis[2-(thiophen-2-yl)quinoxaline-κN4]silver(I) perchlorate
IUCrData, 2023 The crystal of the title salt, [Ag(C12H8N2S)2]ClO4, has C2/c symmetry whereby the silver(I) atom sits on a twofold rotation axis, as does the perchlorate anion, which is disordered about this axis.
Guy Crundwell
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