Results 11 to 20 of about 14,380 (267)
On the Nitration of Quinoxalines (Addendum)
Chemical and Pharmaceutical Bulletin, 1960 2-Hydroxyquinoxaline was nitrated with potassium nitrate in conc. sulfuric acid and formed 2-hydroxy-6-nitroquinoxaline, m.p. 306°, in 77% yield. This was treated with dimethyl sulfate and 1-methyl-2-oxo-6-nitro-1, 2-dihydroquinoxaline, m.p. 213°, was obtained, which was also prepared by the condensation of 1-methylamino-2-amino-4-nitrobenzene with ...
Hirotaka Otomasu, Kei Yoshida
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Alkoxyallene‐Based LANCA Three‐Component Synthesis of 1,2‐Diketones, Quinoxalines, and Unique Isoindenone Dimers and a Computational Study of the Isoindenone Dimerization [PDF]
, 2020 A series of β‐alkoxy‐β‐ketoenamides was prepared by the well‐established LANCA three‐component reaction of lithiated 1‐(2‐trimethylsilylethoxy)‐substituted allenes, nitriles, and α,β‐unsaturated carboxylic acids.
Bera M. K. +6 more
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Bis[2-(thiophen-2-yl)quinoxaline-κN4]silver(I) perchlorate
IUCrData, 2023 The crystal of the title salt, [Ag(C12H8N2S)2]ClO4, has C2/c symmetry whereby the silver(I) atom sits on a twofold rotation axis, as does the perchlorate anion, which is disordered about this axis.
Guy Crundwell
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Quinoxaline: A comprehension of current pharmacological advancement in medicinal chemistry
European Journal of Medicinal Chemistry Reports, 2022 Quinoxaline is a fused heterocycle ring template present in diverse pharmacophore and widely used in medicinal chemistry. Owing to its vast pharmaceutical profile, several quinoxalines analogous displayed their distinct pharmacological activities. In the
Suresh Kumar Suthar +4 more
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InCl3‑Catalyzed One-Pot Synthesis of Pyrrolo/Indolo- and Benzooxazepino-Fused Quinoxalines [PDF]
ACS OmegaNuray Esra Aksakal, Metin Zora
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Microwave assisted synthesis of quinoxaline derivatives
Results in Chemistry, 2023 Substituted quinoxalines are known building blocks for compounds with pharmacological, agricultural, and material uses. Forming carbon-heteroatom bonds at the 2,3-positions on quinoxaline can be challenging. 2,3-chloroquinoxaline can undergo nucleophilic
Lucas K. Beagle +3 more
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Quinoxaline-2-carbonitrile [PDF]
Acta Crystallographica Section E Structure Reports Online, 2009 In the title compound, C9H5N3, the quinoxaline ring is essentially planar, with a maximum deviation of 0.012 (1) Å. Short intermolecular distances between the centroids of the 2,3-dihydropyrazine and benzene rings [3.6490 (5) Å] indicate the existence of π⋯π interactions.
Hoong‐Kun Fun +4 more
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Molecules, 2016 An investigation on the effect of substituent at the 2-position of mono-substituted quinoxalines in the synthesis of di-substituted quinoxaline derivatives via nucleophilic substitution reactions, is reported.
Ndumiso Thamsanqa Ndlovu +1 more
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Recent Advances in Homogeneous Metal-Catalyzed Aerobic C–H Oxidation of Benzylic Compounds [PDF]
, 2018 Csp(3)-H oxidation of benzylic methylene compounds is an established strategy for the synthesis of aromatic ketones, esters, and amides. The need for more sustainable oxidizers has encouraged researchers to explore the use of molecular oxygen.
Domínguez Pérez, Pilar Esther +3 more
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Results in Chemistry, 2023 Medicinal chemistry is a basic science that involves identification, synthesis and development of new drugs for therapeutic use. Biological importance of heterocycles makes them more crucial in pharmaceutical industries.In this work heterocyclics like ...
Geethavani Meka, Ramakrishna Chintakunta
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