Results 21 to 30 of about 14,696 (253)
2,3-Diethylbenzo[g]quinoxaline [PDF]
IUCrData, 2020 The title compound, C16H16N2, was synthesized by dispersing 3,4-hexanedione in a methanol–water solution containing the acid catalyst NH4HF2, then adding 1,2-diaminonaphthalene. The fused-ring system of the title compound is close to planar (r.m.s. deviation = 0.028 Å); one of the pendant methyl C atoms lies close to the ring plane [deviation = 0.071 ...
Guy Crundwell, Ashley Leeds
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Quinoxaline: A comprehension of current pharmacological advancement in medicinal chemistry
European Journal of Medicinal Chemistry Reports, 2022 Quinoxaline is a fused heterocycle ring template present in diverse pharmacophore and widely used in medicinal chemistry. Owing to its vast pharmaceutical profile, several quinoxalines analogous displayed their distinct pharmacological activities. In the
Suresh Kumar Suthar +4 more
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2-(3-Nitrophenoxy)quinoxaline [PDF]
Acta Crystallographica Section E Structure Reports Online, 2010 In the title mol-ecule, C(14)H(9)N(3)O(3), the dihedral angle between the quinoxaline and benzene rings is 77.13 (9)°. The mol-ecule is twisted about the ether-benzene O-C bond, with a C-O-C-C torsion angle of -102.8 (2)°. In the crystal, mol-ecules are linked by C-H⋯O hydrogen bonds, forming layers in the ab plane, with one nitro O atom accepting two ...
Hassan, N.D. +5 more
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Results in Chemistry, 2023 Medicinal chemistry is a basic science that involves identification, synthesis and development of new drugs for therapeutic use. Biological importance of heterocycles makes them more crucial in pharmaceutical industries.In this work heterocyclics like ...
Geethavani Meka, Ramakrishna Chintakunta
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Synthesis and Antimicrobial Activity of Some New Substituted Quinoxalines
Molecules, 2019 A number of new symmetrically and asymmetrically 2,3-disubstituted quinoxalines were synthesized through functionalization of 2,3-dichloroquinoxaline (2,3-DCQ) with a variety of sulfur and/or nitrogen nucleophiles.
Mohamed A. El-Atawy +3 more
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Sinteza i biološko djelovanje novih 1-benzil i 1-benzoil 3-heterocikličkih derivata indola [PDF]
, 2010 Starting from 1-benzyl- (2a) and 1-benzoyl-3-bromoacetyl indoles (2b) new heterocyclic, 2-thioxoimidazolidine (4a,b), imidazolidine-2,4-dione (5a,b), pyrano(2,3-d)imidazole (8a,b and 9a,b), 2-substituted quinoxaline (11a,b–17a,b) and triazolo(4,3-a ...
A. Barry +23 more
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Molecules, 2019 Despite major advancements in the development of various chemotherapeutic agents, treatment for lung cancer remains costly, ineffective, toxic to normal non-cancerous cells, and still hampered by a high level of remissions.
Mixo Aunny Sibiya +5 more
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Acta Crystallographica Section E Structure Reports Online, 2010 A new Z' = 1 crystal structure of quinoxaline (or 1,4-diaza-naphthalene), C(8)H(6)N(2), with one-fifth the volume of the earlier known Z' = 5 structure was obtained by means of an in situ cryocrystallization technique.
Ranganathan, Sathishkumar +3 more
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Functionalization of diazines and benzo derivatives through deprotonated intermediates. [PDF]
, 2008 International audienceThis critical review targets as a readership researchers generally oriented toward organic synthesis and in particular those active in heterocyclic chemistry.
Chevallier, Floris, Mongin, Florence
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Synthesis of new derivants 11h-indeno[1,2-b] - quinoxaline as perspective inhibitors of JNK (C-Jun n-terminalnal kinase) [PDF]
, 2017 Various quinoxalines show biological activity and have such properties as antiviral, antibacterial, antimicrobial, anti-inflammatory, anticancer, antidepressant, vermicidal, and act as inhibitors of kinases [1].
Коврижина, А. Р.
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