Results 21 to 30 of about 26,379 (326)

Quinoxaline-2-carbonitrile [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2009
In the title compound, C9H5N3, the quinoxaline ring is essentially planar, with a maximum deviation of 0.012 (1) Å. Short inter­molecular distances between the centroids of the 2,3-dihydro­pyrazine and benzene rings [3.6490 (5) Å] indicate the existence of π⋯π inter­actions.
Hoong‐Kun Fun   +4 more
openaire   +3 more sources

A Dual-Protein Cascade Reaction for the Regioselective Synthesis of Quinoxalines.

open access: yesOrganic Letters, 2020
In this work, an efficient dual-protein (lipase and hemoglobin) system was successfully constructed for the regioselective synthesis of quinoxalines in water. A set of quinoxalines were obtained in high yields under optimal reaction conditions. This dual-
Fengxi Li   +6 more
semanticscholar   +1 more source

Nucleophilic Substitution on 2-Monosubstituted Quinoxalines Giving 2,3-Disubstituted Quinoxalines: Investigating the Effect of the 2-Substituent

open access: yesMolecules, 2016
An investigation on the effect of substituent at the 2-position of mono-substituted quinoxalines in the synthesis of di-substituted quinoxaline derivatives via nucleophilic substitution reactions, is reported.
Ndumiso Thamsanqa Ndlovu   +1 more
doaj   +1 more source

Biotransformation of quinoxaline by Streptomyces badius [PDF]

open access: yesLetters in Applied Microbiology, 1996
Quinoxaline, a mutagenic azaarene produced in foods during cooking, was added to cultures of Streptomyces badius ATCC 39117. After 24 h, the cultures were extracted with ethyl acetate. Two major metabolites were purified by liquid chromatography and identified by mass spectrometry and nuclear magnetic resonance spectroscopy as 3,4-dihydro-2(1H ...
Sutherland, J. B.   +3 more
openaire   +4 more sources

Induction of Cell Death in Human A549 Cells Using 3-(Quinoxaline-3-yl) Prop-2-ynyl Methanosulphonate and 3-(Quinoxaline-3-yl) Prop-2-yn-1-ol

open access: yesMolecules, 2019
Despite major advancements in the development of various chemotherapeutic agents, treatment for lung cancer remains costly, ineffective, toxic to normal non-cancerous cells, and still hampered by a high level of remissions.
Mixo Aunny Sibiya   +5 more
doaj   +1 more source

Thermochemical and Theoretical Studies of 2-Hydroxyquinoxaline, 2,3-Dihydroxyquinoxaline, and 2-Hydroxy-3-methylquinoxaline [PDF]

open access: yes, 2000
The standard (p° = 0.1 MPa) molar enthalpies of formation for crystalline 2-hydroxyquinoxaline, 2,3-dihydroxyquinoxaline, and 2-hydroxy-3-methylquinoxaline were derived from the standard molar enthalpies of combustion, in oxygen, at T = 298.15 K ...
Matos, M. A. R.   +4 more
core   +1 more source

Dual Allosteric Effect in Glycine/NMDA Receptor Antagonism: A Comparative QSAR Approach

open access: yesPharmaceuticals, 2010
A comparative Hantzsch type QSAR study was conducted using multiple regression analysis on various sets of quinoxalines, quinoxalin-4-ones, quinazoline-2-carboxylates, 4-hydroxyquinolin-2(1H)-ones, 2-carboxytetrahydroquinolines, phenyl-hydroxy-quinolones,
Vipin B. Gupta, Manish Sharma
doaj   +1 more source

Condensation of 4-hydroxy-2-thiazolines with 1,2-phenylenediamine as a novel effective route to thiazolo[3,4-a]quinoxalines [PDF]

open access: yes, 2004
Thiazolo[3,4-a]quinoxalin-4-ones were prepared in two steps starting from methyl phenylchloropyruvate using a new strategy for the construction of the ring system. A key step in this new method involves the reaction of 4-hydroxytetrahydrothiazoles with 1,
Gubaidullin, Aidar T   +4 more
core   +1 more source

Silica Bonded S-Sulfonic Acid: A Recyclable Catalyst for the Synthesis of Quinoxalines at Room Temperature

open access: yesMolecules, 2009
The reaction of 3-mercaptopropylsilica (MPS) and chlorosulfonic acid in chloroform afforded silica bonded S-sulfonic acid (SBSSA), which was used as a catalyst for the room temperature synthesis of quinoxaline derivatives from 1,2-diamino compounds and 1,
Khodabakhsh Niknam   +2 more
doaj   +1 more source

2-(4-Chloroanilino)quinoxaline [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2008
There are two mol-ecules in the asymmetric unit of the title compound, C(14)H(10)ClN(3), with dihedral angles of 5.11 (10) and 13.61 (10)° between the aromatic ring systems. In the crystal structure, mol-ecules are linked by N-H⋯N hydrogen bonds, resulting in chains propagating in [010].
Idris, A.   +4 more
openaire   +5 more sources

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