Results 21 to 30 of about 14,380 (267)
Molecules, 2019 Despite major advancements in the development of various chemotherapeutic agents, treatment for lung cancer remains costly, ineffective, toxic to normal non-cancerous cells, and still hampered by a high level of remissions.
Mixo Aunny Sibiya +5 more
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Sinteza i biološko djelovanje novih 1-benzil i 1-benzoil 3-heterocikličkih derivata indola [PDF]
, 2010 Starting from 1-benzyl- (2a) and 1-benzoyl-3-bromoacetyl indoles (2b) new heterocyclic, 2-thioxoimidazolidine (4a,b), imidazolidine-2,4-dione (5a,b), pyrano(2,3-d)imidazole (8a,b and 9a,b), 2-substituted quinoxaline (11a,b–17a,b) and triazolo(4,3-a ...
A. Barry +23 more
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Functionalization of diazines and benzo derivatives through deprotonated intermediates. [PDF]
, 2008 International audienceThis critical review targets as a readership researchers generally oriented toward organic synthesis and in particular those active in heterocyclic chemistry.
Chevallier, Floris, Mongin, Florence
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2-(4-Chloroanilino)quinoxaline [PDF]
Acta Crystallographica Section E Structure Reports Online, 2008 There are two mol-ecules in the asymmetric unit of the title compound, C(14)H(10)ClN(3), with dihedral angles of 5.11 (10) and 13.61 (10)° between the aromatic ring systems. In the crystal structure, mol-ecules are linked by N-H⋯N hydrogen bonds, resulting in chains propagating in [010].
Idris, A. +4 more
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Molecules, 2009 The reaction of 3-mercaptopropylsilica (MPS) and chlorosulfonic acid in chloroform afforded silica bonded S-sulfonic acid (SBSSA), which was used as a catalyst for the room temperature synthesis of quinoxaline derivatives from 1,2-diamino compounds and 1,
Khodabakhsh Niknam +2 more
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Dual Allosteric Effect in Glycine/NMDA Receptor Antagonism: A Comparative QSAR Approach
Pharmaceuticals, 2010 A comparative Hantzsch type QSAR study was conducted using multiple regression analysis on various sets of quinoxalines, quinoxalin-4-ones, quinazoline-2-carboxylates, 4-hydroxyquinolin-2(1H)-ones, 2-carboxytetrahydroquinolines, phenyl-hydroxy-quinolones,
Vipin B. Gupta, Manish Sharma
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Biotransformation of quinoxaline by Streptomyces badius [PDF]
Letters in Applied Microbiology, 1996 Quinoxaline, a mutagenic azaarene produced in foods during cooking, was added to cultures of Streptomyces badius ATCC 39117. After 24 h, the cultures were extracted with ethyl acetate. Two major metabolites were purified by liquid chromatography and identified by mass spectrometry and nuclear magnetic resonance spectroscopy as 3,4-dihydro-2(1H ...
Sutherland, J. B. +3 more
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Molecules, 2014 10-Ethyl-7-oxo-7,10-dihydropyrido[2,3-f]quinoxaline derivatives, synthesized as promising biologically/photobiologically active compounds were characterized by UV/vis, FT-IR and fluorescent spectroscopy.
Zuzana Barbieriková +5 more
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Synthesis and Antimicrobial Activity of Some New Substituted Quinoxalines
Molecules, 2019 A number of new symmetrically and asymmetrically 2,3-disubstituted quinoxalines were synthesized through functionalization of 2,3-dichloroquinoxaline (2,3-DCQ) with a variety of sulfur and/or nitrogen nucleophiles.
Mohamed A. El-Atawy +3 more
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, 2023 Quinoxalines are a group of antibiotics widely used in medicine to fight bacterial infections.These antibiotics have a broad spectrum of action and belong to the class of 4 quinolones. Theirmechanism of action is based on inhibiting the activity of bacterial enzymes responsible for DNAsynthesis, which leads to their death. Due to this, quinoxalines are
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